A5115604962- Viral Infections and Vectors
- Bacteriophages and microbial interactions
- Vector-Borne Animal Diseases
- Influenza Virus Research Studies
- SARS-CoV-2 detection and testing
- Fire effects on ecosystems
- Advanced biosensing and bioanalysis techniques
- Nanopore and Nanochannel Transport Studies
- Microbial infections and disease research
- Respiratory viral infections research
- Genomics and Phylogenetic Studies
- Animal Disease Management and Epidemiology
- Molecular Biology Techniques and Applications
- Bacterial biofilms and quorum sensing
- Antimicrobial Resistance in Staphylococcus
- Biochemical and Structural Characterization
- Periodontal Regeneration and Treatments
- Oral microbiology and periodontitis research
- Bacillus and Francisella bacterial research
- Radiomics and Machine Learning in Medical Imaging
- Temporomandibular Joint Disorders
- Tuberculosis Research and Epidemiology
- Advanced Memory and Neural Computing
- Ferroelectric and Negative Capacitance Devices
- Viral gastroenteritis research and epidemiology
Hangzhou Center for Disease Control and Prevention
2019-2025
Hainan Medical University
2024
Capital Medical University
2022-2024
Zhejiang Center for Disease Control and Prevention
2020-2023
Capital University
2022
Institute of Microbiology
2016-2017
Anhui Medical University
2016
Abstract To assess biofilm formation ability and identify differences in the prevalence of genes involved among Staphylococcus aureus strains isolated from different food samples, 97 S. was evaluated using a colorimetric microtiter plate assay. Thirteen encoding microbial surface components recognizing adhesive matrix molecules, intracellular adhesion were detected by PCR specific primers. Approximately 72% isolates produced biofilms. Among these isolates, 54.64% weak producers, while 14.43%...
The novel SARS-CoV-2 outbreak has swiftly spread worldwide. rapid genome sequencing of strains become a helpful tool for better understanding the genomic characteristics and origin virus. To obtain virus whole-genome sequences directly from clinical specimens, we performed nanopore using modified ARTIC protocol in portable sequencer validated routine 8-h workflow 5-h pipeline. We conducted some optimization to improve workflow. sensitivity was also tested by serially diluting RNA samples....
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease sporadic occurrence and high mortality. Herein, we report example of the in-hospital transmission SFTS virus (SFTSV) infections familial nosocomial clustering in Zhejiang Province, eastern China, from March to April 2023. The epidemiological investigation genomic analysis revealed that at least eight suspected cases occurred this cluster, including one death asymptomatic case. Our reemphasizes...
This study examined the genetic and evolutionary features of influenza A/H3N2 viruses in Hangzhou (2010–2022) by analyzing 28,651 influenza-like illness samples from two sentinel hospitals. Influenza coexisted with other subtypes, dominating seasonal peaks (notably summer). Whole-genome sequencing 367 strains was performed on GridION platforms. Phylogenetic analysis showed they fell into 16 groups, multiple clades circulating simultaneously. Shannon entropy indicated HA, NA, NS gene segments...
Abstract The outbreak of the novel SARS-CoV-2 has swiftly spread worldwide. Rapid genome sequencing strains become a helpful tool for better understanding virus genomic characteristics and origin. To obtain whole-genome sequence directly from clinical specimens, we performed nanopore using modified ARTIC protocol on portable sequencer, validated routine 8 hours workflow 5 rapid pipeline. We had made some optimizations to improve workflow. sensitivity was also tested by serially diluting RNA...
ABSTRACT Severe fever with thrombocytopenia syndrome (SFTS), a tick‐borne infectious disease caused by the SFTS virus (SFTSV), is becoming significant public health threat due to its high mortality rate. Knowledge of SFTSV in southeastern coastal China limited. The whole genomes 66 strains collected from 2013 2023 Hangzhou, city China, were amplified and sequenced elucidate geography‐related genetic pathogenic diversity. Hangzhou SFTSVs could be classified into five pure genotype groups (A,...
We report here the whole-genome sequence of a new Enterococcus faecalis phage, vB_EfaS_IME197, which has linear double-stranded DNA genome 41,307 bp with 34% G+C content. describe main features vB_EfaS_IME197.
a repulsive obligate blood feeder, is three-host tick inflicting tremendous damage. Blood-sucking initiates tick-pathogen-host interactions along with alterations in the expression levels of numerous bioactive ingredients. Key molecules regulating meals were identified using transcriptomic approach. A total number 744 transcripts showed statistically significantly differential including 309 upregulated and 435 downregulated semiengorged female ticks compared to unfed ticks, all collected...
This article describes an interdisciplinary treatment that helped a patient with displaced upper anterior teeth. A gingivectomy, root canal therapies, digital smile design, wax-up, and guided tooth preparations were applied.
Background & objectives: Biting midges are hematophagous arthropods responsible for zoonotic infectious diseases and have a wide distribution in temperate tropical latitudes of the world. Methods: The genomic DNA midge samples was extracted using Chelex method ITS1gene amplified by PCR to identify species via BLAST. sequence characteristics genetic diversity were analyzed ClustalOmega, DnaSP, Arlequin, PopART, TCS software tool. validity ITS1 gene as barcode marker evaluated DAMBE....
The special any-polar resistive switching mode includes the coexistence and stable conversion between unipolar bipolar under same compliance current. In present work, is demonstrated when thin Ti intercalations are introduced into both sides of Pt/HfO 2 /Pt RRAM device. role contributes to fulfillment working mechanism, which lies in filament constructed by oxygen vacancies effective storage ion at electrode interface.
Objective To investigate the genomic characteristics and virulence factors of emetic-type Bacillus cereus strains isolated from food in Hangzhou for better understanding their pathogenic potential. Methods Real-time PCR was performed to detect ces gene cluster (cereulide) 132 2015 2017. Genomes cereulide-positive were sequenced using Illumina MiSeq sequencing platform. Genome annotation, factor detection, comparative evolutionary analysis after sequences genomes...