A5028236691- Cancer, Hypoxia, and Metabolism
- Metabolism, Diabetes, and Cancer
- Oral and Maxillofacial Pathology
- RNA modifications and cancer
- Ubiquitin and proteasome pathways
- Recycling and Waste Management Techniques
- Cancer-related gene regulation
- Chemokine receptors and signaling
- Head and Neck Cancer Studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Forest ecology and management
- Ear and Head Tumors
- dental development and anomalies
- Cancer Cells and Metastasis
- Cancer Immunotherapy and Biomarkers
- Dental Radiography and Imaging
- Epigenetics and DNA Methylation
- Cancer-related Molecular Pathways
- Amino Acid Enzymes and Metabolism
- Soil Carbon and Nitrogen Dynamics
- Microplastics and Plastic Pollution
- Plant Water Relations and Carbon Dynamics
- Cancer-related molecular mechanisms research
Liaoning Technical University
2023
Sun Yat-sen University
2015-2021
Guangzhou Medical University
2021
Stomatology Hospital
2017-2021
Third Affiliated Hospital of Sun Yat-sen University
2021
Hospital of Stomatology, Sun Yat-sen University
2017-2018
Chemokine ( CC motif) ligand 18 CCL 18) is involved in remodeling of the tumor microenvironment and plays critical roles oncogenesis, invasiveness, metastasis. We previously investigated overexpression primary oral squamous cell carcinoma OSCC ) tissues its association with advanced clinical stage patients. However, underlying mechanisms this 18‐derived activity remains unidentified. This study showed exogenous increased migration invasion induced epithelial–mesenchymal transition EMT ),...
Microplastics are persistent and complex contaminants have been recognized as a global concern. Recently, increasing efforts devoted to studying the influence of microplastics on soils. However, complexity diversity extraction methods result in lack systematic analysis comprehensive review this field. In paper, we used CiteSpace software summarize development Then, visualized analyzed knowledge structure, research hotspots, trend directions We found that number publications escalated...
Oral squamous cell carcinoma (OSCC) is the most common and aggressive epithelial tumor in head neck region with a rising incidence. Despite advances basic science clinical research, overall survival rate of OSCC remains low. Thus finding novel effective therapeutic agents for necessary. In this study, we investigated effects mechanisms combined metformin 4SC-202 OSCC. Our results showed that synergistically suppressed proliferation promoted intrinsic apoptosis cells vitro vivo. Importantly,...
It is a consensus that symptomatic impacted mandibular third molars (MTMs) need to be removed. Although the prophylactic extraction of asymptomatic MTMs remains controversial. This study aims investigate effects on themselves and adjacent teeth pathophysiology provide evidence for MTMs.A retrospective panoramic radiographs patients visited Affiliated Stomatology Hospital Guangzhou Medical University from April 2014 May 2018 was conducted dental periodontal lesions in second (MSMs), as well...
Abstract Radiotherapy for nasopharyngeal carcinoma has been reported to cause second primary oral squamous cell (s‐OSCC). The prognosis and pathologic characteristic of s‐OSCC are largely unknown. Bmi1 was associated with the repair radiation‐induced DNA damage, suggesting its possible involvement in process s‐OSCC. Herein, we compared between OSCC (p‐OSCC) explored development. In this retrospective study, p‐OSCC patients were matched by propensity scores. Their outcomes univariate...
Proline rich 11 (PRR11) serves an important role in the development and progression of a number types human cancer. However, clinical PRR11 tongue squamous cell carcinoma (TSCC) remains unknown. The present study aimed to investigate expression clinicopathological significance TSCC. Cancer Genome Atlas analysis demonstrated that upregulation TSCC correlated with poor prognosis. data revealed mRNA protein was markedly upregulated tissues. Immunohistochemistry on 72 archived paraffin‑embedded...
The monocarboxylate transporters (MCTs) family, especially MCT1, plays an important role in tumor metabolism. MCT1 mediates a variety of monocarboxylic acids across the plasma membrane, and determines to take or export lactic acid according metabolic state, thus maintaining special cells metabolism model. Considering emerging evidence for genesis, metabolism, invasion metastasis, is expected be new target cancer therapy. Key words: Neoplasms; Metabolism; Monocarboxylate transporter 1
In the semiarid sandy region of Northeast China, Mongolian pine (Pinus sylvestris var. mongolica) suffers dieback after age 35, while Japanese red densiflora) and Chinese tabuliformis) stay healthy. Foliar nutrient retranslocation reflects conservation utilization mechanism plants in response to their habitats. However, strategies employed by three Pinus tree species cope with limitations remain largely unknown. For this study, we investigated seasonal variations nitrogen (N) phosphorus (P)...
Objective To understand expression of ROS/Trx-1 feedback loop that induced by hypoxia and their effects on the invasion oral squamous cell carcinoma (OSCC) cells. Methods CAL33 HSC6 cells (two lines OSCC) were cultured under normoxic hypoxic condition. Then ROS Trx-1 detected 2, 7-dichlorodihydrofluoresceindiacetate (DCFH-DA) assay Western blot, respectively. Subsequently, level was tested after specially inhibiting expression. The results analyzed with student-t test. Transwell...