A5010456669- Lymphoma Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Chronic Lymphocytic Leukemia Research
- Acute Lymphoblastic Leukemia research
- Viral-associated cancers and disorders
- Chronic Myeloid Leukemia Treatments
- CNS Lymphoma Diagnosis and Treatment
- Lung Cancer Research Studies
- Multiple Myeloma Research and Treatments
- Hematopoietic Stem Cell Transplantation
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Neuroendocrine Tumor Research Advances
- Hematological disorders and diagnostics
- Venous Thromboembolism Diagnosis and Management
- Cancer Treatment and Pharmacology
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Neutropenia and Cancer Infections
- Retinoids in leukemia and cellular processes
- Rheumatoid Arthritis Research and Therapies
- Osteoarthritis Treatment and Mechanisms
- Immune cells in cancer
- Liver Diseases and Immunity
- Medical History and Research
- Single-cell and spatial transcriptomics
University of Florida
2017
Leipzig University
2012
University Hospital Magdeburg
1975-2008
Klinikum Magdeburg
2002-2006
Otto-von-Guericke University Magdeburg
1995-2005
Helios Klinikum Erfurt
2003
An increased risk for thromboembolism in cancer patients has been observed with solid tumours, whereas little data exist on malignant lymphoma. We found an overall thromboembolic event incidence of 7.7% 1038 lymphoma treated our institution, a statistically significantly higher high-grade than low-grade
Patients with malignancies have an increased risk for venous thromboembolisms (VTE), but data on patients acute leukaemia are very limited so far. We found VTE in 12% of 455 leukaemia, half which occurred association central catheters, equal ALL and AML.
Background: People with primary sclerosing cholangitis (PSC) have a 20% lifetime risk of biliary tract cancer (BTC). Using whole-exome sequencing, we characterized genomic alterations in tissue samples from BTC underlying PSC. Methods: We extracted DNA formalin-fixed, paraffin-embedded tumor and paired nontumor 52 resection or biopsy specimens patients PSC performed sequencing. Following copy number analysis, variant calling, filtering, putative PSC-BTC-associated genes were assessed by...
Background: Characteristic features of multiple myeloma are bone resorption, osteoporosis and osteolytic lesions. Bisphosphonates can inhibit osteoclast activity resorption. In this controlled randomized multicenter trial the effect bisphosphonate clodronate on progression involvement in was evaluated. Patients Methods: 170 patients with requiring treatment were recruited randomized. All received 15 mg/m2 i.v. melphalan day 1 60 p.o. predisone days 1-4 every 4 weeks. to arm 1,600 mg p.o./day...
Background: As part of the attempt to optimize treatment high-grade non-Hodgkin's lymphoma (NHL) in advanced stages, a pilot study was designed investigate feasibility and efficacy BMMP protocol (bendamustine, methotrexate, mitoxantrone, prednisolone). Material Methods: Between October 1994 September 1996,23 elderly patients (median age 60.1 years; range: 20-80 years) with nonresponding or relapsed NHL were treated according protocol. Response toxicity determined on basis WHO criteria....
SummaryAdjuvant arthritis has so far been observed only in rats. It was attempted successfully to induce this disease mice and hamsters. The incidence of 28 per cent. In comparison the rats, course tended be milder biphasic; symptoms on front paws were relatively severe. period latency histological picture resembled those is concluded that adjuvant a non-species-specific form delayed hypersensitivity reaction, antigen which as yet unknown.
Abstract In general, the mobilization of peripheral blood progenitor cells (PBPC) in multiple myeloma (MM) patients is poor and achieved most cases by combined cyclophosphamide G‐CSF. This study was performed to examine efficacy ifosfamide/epirubicine G‐CSF for PBPC purging. Sixteen suffering from stage II/A III/A according Durie Salmon underwent chemotherapy consisting a total three cycles ifosfamide (3 g/m 2 on days 1 epirubicine 80 mg/m day 1) (10 or 20 µg/kg body weight (BW) daily until...
Micronodular lesions are common findings in lung imaging. As an important differential diagnosis, we describe a case of diffuse idiopathic pulmonary neuroendocrine cell hyperplasia; it is notable that the diagnosis hyperplasia often delayed. This provides supporting evidence to establish biopsy by cryotechnique as option first choice when considering diagnostic strategy for micronodular lesions.We report 65-year-old white woman who presented with obstructive symptoms chronic coughing and...
Idarubicin is the first anthracycline that can be administered orally facilitating antineoplastic chemotherapy at an improved quality of life. In different studies idarubicin has proved clinical effectiveness in patients with advanced low grade non Hodgkin's lymphoma. We performed a phase II study 19 untreated and pretreated B-CLL Binet stage A-C. Idarubucin was dose 15mg/m2 over 3 days every 4 weeks. Of evaluable (m:f, 16:3, median age 64 years, range 41-80 years) 7 were previously while 12...
<b><i>Background:</i></b> Phase I and II studies utilizing the chimeric anti-CD 20 antibody rituximab demonstrate good results in relapsed resistant follicular low-grade lymphoma; combination with cyclophosphamide, doxorubicin, vincristine, prednisone (CHOP) chemotherapy excellent remission rates survival data have been achieved. These justify to evaluate efficacy toxicity of a comparison standard alone prospective randomized trial. Included this study are untreated patients advanced...
Drei Deutsche jüdischer Herkunft, Alfred Neumann (1865-1920), Moritz Katzenstein (1872-1932) und Max Marcus (1892-1983), waren zwischen 1903 1933 in Kontinuität Chefärzte der 2. chirurgischen Klinik des Krankenhauses im Friedrichshain. Ihre fachlichen Leistungen sind Erinnerung wert. A. publizierte als Schüler von Eugen Hahn viel zur Therapie abdominaler Notfälle. Mit nach ihm benannten Netzmanschette wird die Drainage perforierten Ulcus pylori umhüllt, wenn keine andere möglich ist. M....