A5100437887- Advanced biosensing and bioanalysis techniques
- RNA Interference and Gene Delivery
- Advanced Photocatalysis Techniques
- Biosensors and Analytical Detection
- Click Chemistry and Applications
- Nanomaterials for catalytic reactions
- Gold and Silver Nanoparticles Synthesis and Applications
- MXene and MAX Phase Materials
- Copper-based nanomaterials and applications
- ZnO doping and properties
- Advanced Nanomaterials in Catalysis
- 2D Materials and Applications
- Organometallic Complex Synthesis and Catalysis
- Electrocatalysts for Energy Conversion
- Synthetic Organic Chemistry Methods
- Ga2O3 and related materials
- Trace Elements in Health
- Nanomaterials and Printing Technologies
- Modular Robots and Swarm Intelligence
- Carbon dioxide utilization in catalysis
- Polydiacetylene-based materials and applications
- biodegradable polymer synthesis and properties
- Synthesis and Properties of Aromatic Compounds
- Supramolecular Self-Assembly in Materials
- Magnetic Properties and Synthesis of Ferrites
Hunan University
2011-2025
Technological University of the Shannon: Midlands Midwest
2024
First Affiliated Hospital of GuangXi Medical University
2024
Guangxi Medical University
2024
Hohai University
2024
Shanghai Sixth People's Hospital
2024
Shanghai Jiao Tong University
2024
Central South University
2024
University of Science and Technology Beijing
2022
Zhoukou Normal University
2022
Abstract Engineering of the cell plasma membrane using functional DNA is important for studying and controlling cellular behaviors. However, most efforts to apply artificial interactions on cells are limited external surface due lack suitable synthetic tools engineer intracellular side, which impedes many applications in biology. Inspired by natural extracellular vesicle‐cell fusion process, we have developed a fusogenic spherical nucleic acid construct realize robust functionalization both...
Infected wounds pose a significant clinical challenge due to bacterial resistance, recurrent infections, and impaired healing. Reactive oxygen species (ROS)-based strategies have shown promise in eradicating infections. However, the excess ROS infection site after treatments may cause irreversible damage healthy tissues. To address this issue, we developed bovine serum albumin-iridium oxide nanoclusters (BSA-IrO
Treatment of rare earth metal trialkyl complexes Ln(CH2SiMe3)3(THF)2 (Ln = Sc, Lu, and Y) with 1 equiv α-diimine ligands 2,6-R2C6H3N═CH−CH═NC6H3R2-2,6 (R iPr, Me) affords straightforwardly monoanionic iminoamido dialkyl [2,6-R2C6H3N−CH2−C(CH2SiMe3)═NC6H3R2-2,6]Ln(CH2SiMe3)2(THF) (1: Ln R iPr; 2: 3: Y, 4: Me; 5: 6: in 65−85% isolated yields. X-ray analyses show these have decreasing steric hindrance the coordination spheres centers order > 2 3 4 5 6. A mechanism involving intramolecular alkyl...
A series of half-sandwich fluorenyl (Flu′) scandium dialkyl complexes Flu′Sc(CH2SiMe3)2(THF)n (1, Flu′ = C13H9, n 1; 2, 2,7-tBu2C13H7, 3, 9-SiMe3C13H8, 4, 2,7-tBu2-9-SiMe3C13H6, 5, 9-CH2CH2NMe2C13H8, 0; 6, 2,7-tBu2-9-CH2CH2NMe2C13H6, 0) have been synthesized and structurally characterized. In comparison with the well-known cyclopentadienyl-ligated catalyst system [(C5Me4SiMe3)Sc(CH2SiMe3)2(THF)]/[Ph3C][B(C6F5)4], analogous combinations fluorenyl-ligated, THF-containing 1–4 [Ph3C][B(C6F5)4]...
In this study, a novel paper-based SERRS immunoassay based on magnetic separation and alkaline phosphatase (ALP) enzyme catalyzed hydrolysis reaction was developed. By using modified antibodies conjugated to beads, capture of mouse IgG followed by addition ALP-labeled would form sandwich-like immunoconjugate. After separation, 5-bromo-4-chloro-3-indolyl phosphate (BCIP), low active compound, added as the substrate for ALP generate high response. Detection conducted silver colloid/PVP/filter...
Autophagy and apoptosis are closely associated with various pathological physiological processes in cell cycles. Investigating the dynamic changes of intracellular active molecules autophagy is great significance for clarifying their inter-relationship regulating mechanism many diseases. In this study, we develop a dual-ratiometric fluorescent nanoprobe quantitatively differentiating process superoxide anion (O2•–) pH HeLa cells. A rhodamine B-loaded mesoporous silica core was used as...
An obstacle to conducting diverse bioorthogonal reactions in living systems is the sensitivity of artificial metal catalysts. It has been reported that metallocatalysts can be assembled "cleaner" environments cells for stabilized performance, which powerful but limited by prerequisite using specific cells. We report here a strategy establish membrane-anchored catalysts with precise spatial control via liposome fusion-based transport (MAC-LiFT), loading catalytic complexes onto either or both...
Single-atom nickel site-modified Si nanowires are utilized for photoelectrocatalytic CO 2 reduction to achieve nearly 100% selective generation.
Insulin-like growth factor 2 mRNA binding protein 1 (IGF2BP1), as a newly identified N6-methyladenosine (m6A) methylation reader, plays key role in stability, alternative splicing, and translation. However, the function of IGF2BP1 its target genes development male germ cells remains unclear. In present study, Western blotting, immunofluorescence, other cellular methods were used to confirm whether is expressed throughout germline with high abundance spermatogonia mice, downregulation...
Cell-surface glycosylation contains abundant biological information that reflects cell physiological state, and it is of great value to image cell-surface elucidate its functions. Here we present a hybridization chain reaction (HCR)-based multifluorescence resonance energy transfer (multi-FRET) method for specific imaging glycosylation. By installing donors through metabolic glycan labeling acceptors aptamer-tethered nanoassemblies on the same glycoconjugate, intramolecular multi-FRET occurs...
Substrate selectivity is one of the most attractive features natural enzymes from their "bind-to-catalyze" working flow and thus a goal for development synthetic enzyme mimics that mediate abiotic transformations. However, despite recent success in preparation substrate-selective based on single-chain nanoparticles, examples extending such into living systems have been absent. In this article, we report cellulo substrate an enzyme-mimicking macromolecular catalyst cationic dense-shell...
Highly sensitive detection of cancer cells with high signal-to-background ratio (SBR) is still urgently needed. Here, a self-assembling activatable probe (SAAP) based on split aptamers was developed to meet this purpose. The SAAP formed quenched fluorescence; only when target are present would the self-assemble together and thus activate fluorescence by intramolecular intermolecular quenching strategies. As proof concept, aptamer pair stemming from an intact aptamer, ZY11, our lab selected...
The reduction of Cu(OH)2 by hydrazine in a concentrated NaOH solution containing ethylenediamine at 70 °C has been employed to prepare Cu nanowires. net change during nanowire synthesis is that the consumption and gives rise formation nanowires, N2 H2O, which make it possible for us endlessly reuse produced wastewater after removal By controlling re-added amounts case reusing wastewater, we have found morphology nanowires kept almost unchanged even though recycled more than ten times....
A practical palladium-mediated cascade Tsuji-Trost reaction/Heck coupling of N-Ts o-bromoanilines with 4-acetoxy-2-butenonic acid derivatives using a Pd(OAc)2/P( o-tol)3/DIPEA system is described for straightforward synthesis indole-3-acetic derivatives. This methodology was successfully applied to synthesize various substituted indole/azaindole-3-acetic and Almotriptan, which drug the acute treatment migraines. Moreover, plausible cyclization mechanism has been proposed.
Ovalene's nitrogenated derivative with all zigzag edges and nitrogen atom doping at the periphery has been developed via one-step nitrogenation of formylbisanthene. Because incorporation, these molecules show greatly decreased highest occupied molecular orbital levels, enhanced intermolecular interactions, a reversible acid response. Aza-ovalene also exhibits diatropic ring current along periphery. This work provides rare examples all-zigzag-edged N-polycyclic aromatic hydrocarbons.
Heterostructure catalysts are highly anticipated in the field of photocatalytic water splitting. AlN/Sc2CF2 and GaN/Sc2CF2 heterostructures proposed this work, electronic structures were revealed with first-principles method to explore their properties for The results found that thermodynamically stable indirect semiconductors reduced band gaps 1.75 eV 1.84 eV, respectively. These two have been confirmed type-Ⅰ alignments, both VBM CBM contributed by Sc2CF2 layer. exhibit potential splitting...
MnFe2O4 nanocrystals with spinel structure were prepared by conventional solution combustion synthesis and salt-assisted synthesis, respectively, their adsorption capacities for Congo red (CR) also investigated. The results showed that the KCl salt (K-MFO) exhibited much better capacity CR than those without (MFO), because introduction of into process in an obvious dispersion increment surface area obtained particles. Meanwhile, a clearly ferromagnetic behavior under applied magnetic field,...
Abstract Atom-transfer radical polymerization (ATRP) is a well-known technique for controlled polymer synthesis. However, the ATRP usually employed toxic heavy metal ionas as catalyst and was susceptible to molecular oxygen, which made it should be conducted under strictly anoxic condition. Conducting ambient biocompatible conditions major challenge. In this study, cytochrome C explored an efficient biocatalyst conditions. The catalyzed showed relatively low dispersity index of 1.19. More...
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