Zhuo Yu

ORCID: 0009-0007-8532-3747
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • RNA modifications and cancer
  • Esophageal Cancer Research and Treatment
  • Epigenetics and DNA Methylation
  • Chromosomal and Genetic Variations
  • Animal Genetics and Reproduction
  • Extracellular vesicles in disease
  • Cancer Genomics and Diagnostics
  • interferon and immune responses
  • Pain Mechanisms and Treatments
  • Adenosine and Purinergic Signaling
  • MicroRNA in disease regulation
  • Plant Gene Expression Analysis
  • Protease and Inhibitor Mechanisms
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Genetic diversity and population structure
  • Cancer Cells and Metastasis
  • Fish Biology and Ecology Studies
  • Aquaculture disease management and microbiota
  • NF-κB Signaling Pathways
  • Aquaculture Nutrition and Growth
  • Cell Adhesion Molecules Research
  • Immune Response and Inflammation
  • Macrophage Migration Inhibitory Factor
  • CRISPR and Genetic Engineering
  • Mechanisms of cancer metastasis

National Clinical Research
2025

Air Force Medical University
2024-2025

Dalian Ocean University
2010-2024

Qingdao National Laboratory for Marine Science and Technology
2024

Inner Mongolia Agricultural University
2024

University of Hong Kong
2008-2011

Hong Kong University of Science and Technology
2008

Abstract Background Pulpitis is a prevalent oral disease characterized by severe pain. The activation of microglia in the medullary dorsal horn (MDH) reportedly essential for central sensitization mechanism associated with pulpitis. P2X7 receptor (P2X7R) on can trigger secretion exosomes enriched IL-1β, which involved inflammation. Thus, we hypothesized that enhanced exosome regulated microglial P2X7R MDH contributes to pulpitis-induced Methods An experimental pulpitis model was established...

10.1186/s13578-025-01363-4 article EN cc-by Cell & Bioscience 2025-02-22

Pulpitis is a common oral disease associated with severe pain, which often accompanied by sleep disturbances and anxiety-like symptoms. There currently no specific analgesic medication available to alleviate pulpitis-induced pain. In the current study, we applied transcriptomics conduct bioinformatics screening of trigeminal ganglion (TG) medullary dorsal horn (MDH) over 7-day period pulp exposure, aiming identify key differentially expressed genes (DEGs). We identified three DEGs in TG MDH,...

10.1021/acsomega.4c11486 article EN cc-by-nc-nd ACS Omega 2025-03-14

The GATA gene family belongs to a kind of transcriptional regulatory protein featuring zinc finger motif, which is essential for plant growth and development. However, the identification in tetraploid potato still not performed. In present research, total 88

10.3389/fpls.2024.1330559 article EN cc-by Frontiers in Plant Science 2024-03-21

Abstract Loss of chromosome 13q regions in esophageal squamous cell carcinoma (ESCC) is a frequent event. Monochromosome transfer approaches provide direct functional evidence for tumor suppression by 13 SLMT-1, an ESCC line, and identify critical at 13q12.3, 13q14.11, 13q14.3. Differential gene expression profiles three tumor-suppressing microcell hybrids (MCH) their tumorigenic parental SLMT-1 line were revealed competitive hybridization using 19k cDNA oligonucleotide microarrays. Nine...

10.1158/1541-7786.mcr-07-0154 article EN Molecular Cancer Research 2008-04-01

<title>Abstract</title> Background Pulpitis is a prevalent oral disease characterized by severe pain. The activation of microglia in the medullary dorsal horn (MDH) reportedly essential for central sensitization mechanism associated with pulpitis. And P2X7 receptor (P2X7R) on can trigger secretion exosome enriched IL-1β, which involved inflammation. Thus, we hypothesized that enhanced regulated microglial P2X7R MDH contributes to pulpitis-induced Methods male SD rats were chosen as...

10.21203/rs.3.rs-4816069/v1 preprint EN Research Square (Research Square) 2024-09-13

&lt;div&gt;Abstract&lt;p&gt;Loss of chromosome 13q regions in esophageal squamous cell carcinoma (ESCC) is a frequent event. Monochromosome transfer approaches provide direct functional evidence for tumor suppression by 13 SLMT-1, an ESCC line, and identify critical at 13q12.3, 13q14.11, 13q14.3. Differential gene expression profiles three tumor-suppressing microcell hybrids (MCH) their tumorigenic parental SLMT-1 line were revealed competitive hybridization using 19k cDNA oligonucleotide...

10.1158/1541-7786.c.6541525 preprint EN 2023-04-03

&lt;div&gt;Abstract&lt;p&gt;Loss of chromosome 13q regions in esophageal squamous cell carcinoma (ESCC) is a frequent event. Monochromosome transfer approaches provide direct functional evidence for tumor suppression by 13 SLMT-1, an ESCC line, and identify critical at 13q12.3, 13q14.11, 13q14.3. Differential gene expression profiles three tumor-suppressing microcell hybrids (MCH) their tumorigenic parental SLMT-1 line were revealed competitive hybridization using 19k cDNA oligonucleotide...

10.1158/1541-7786.c.6541525.v1 preprint EN 2023-04-03
Coming Soon ...