A5107938160- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Cancer-related molecular mechanisms research
- Electromagnetic wave absorption materials
- Advanced biosensing and bioanalysis techniques
- Cancer Risks and Factors
- Pharmacological Effects of Natural Compounds
- Material Properties and Applications
- Maternal and Perinatal Health Interventions
- MicroRNA in disease regulation
- Natural product bioactivities and synthesis
- Traditional Chinese Medicine Analysis
- Estrogen and related hormone effects
- Assisted Reproductive Technology and Twin Pregnancy
- Endometriosis Research and Treatment
- Global Maternal and Child Health
- Kruppel-like factors research
- Advanced Graph Neural Networks
- Polysaccharides and Plant Cell Walls
- Menstrual Health and Disorders
- 14-3-3 protein interactions
- Nutrition, Health and Food Behavior
- Fibroblast Growth Factor Research
- Pomegranate: compositions and health benefits
- Intraperitoneal and Appendiceal Malignancies
Obstetrics and Gynecology Hospital of Fudan University
2016-2025
Cornell University
2024
Beijing University of Chinese Medicine
2023-2024
Guilin Medical University
2024
Hefei University of Technology
2024
Syracuse University
2024
Institute of Oceanographic Instrumentation
2024
Shandong Academy of Sciences
2024
Qilu University of Technology
2024
Hong Kong Baptist University
2024
Lung adenocarcinoma (LUAD) is the most prevalent subtype of non-small cell lung cancer. Additionally, disulfidptosis, a newly discovered type death, has been found to be closely associated with onset and progression tumors. The study first identified genes related disulfidptosis through correlation analysis. These were then screened using univariate cox regression LASSO regression, prognostic model was constructed multivariate regression. A nomogram also created predict prognosis LUAD....
As an emerging type of pollutant, microplastics have become a global environmental problem. Approximately, fifth the burden 2 diabetes can be attributed to air particulate pollution. However, scientific knowledge remains limited about effects airborne nanoplastics (NPs) exposure on metabolic diseases. In this experiment, whole-body system was used simulate real atmospheric environment, and three concentrations combined with actual concentration were selected explore NPs Based histological...
Abstract Several miRNAs have recently been identified to regulate adipocyte or osteoblast differentiation both. In this study, miR-223 was found be involved in the reciprocal regulation of and differentiation. induced primary cultured mouse marrow stromal cell, mesenchymal line C3H10T1/2 ST2 after adipogenic treatment. Conversely, it reduced preosteoblast MC3T3-E1 osteogenic Supplementing levels using synthetic mimics significantly suppressed growth cells progenitor fully differentiate into...
// Fang Shen 1 , Yifei Gao Jingxin Ding Qi Chen 1, 2 The Hospital of Obstetrics & Gynaecology, Fudan University, China Department University Auckland, New Zealand Correspondence to: Chen, email: q.chen@auckland.ac.nz Ding, djxdd@sina.com Keywords: endometrial cancer, type and 2, ER, PR, menopause Received: August 23, 2016 Accepted: November 15, Published: 19, 2016 ABSTRACT Endometrial cancer is a major in women traditionally divided into 2. It well known...
Abstract Recent emerging studies of miRNAs in adipocyte commitment provide new insights to understand the molecular basis adipogenesis. The current study indicated that miR-140-5p was altered primary cultured marrow stromal cells and established progenitor lines after adipogenic and/or osteogenic treatment. increased adipose tissue db/db obese mice vs. lean mice. Supplementing activity induced cell ST2 preadipocyte 3T3-L1 differentiate into mature adipocytes. Conversely, inhibition...
Abstract The estrogen (ER) or progesterone receptors (PR) is positively associated with better clinical outcomes in ovarian cancer. Whether metastasis recurrence of cancer correlated this association has not been investigated. Data on 894 women epithelial were collected and the between ER PR positivity peritoneal lymph node metastases was analysed. higher high-grade, low-grade serous endometrioid carcinoma, but lower mucinous clear-cell carcinoma. Significantly seen carcinoma high-grade...
The incidence of endometrial cancer depends in part on the ethnicity and geographical area which woman resides. Menopause status is a well-known risk factor for most cases occur after menopause. It is, however, less clear how menopause associated with including its subtypes Chinese women.Data 1,746 women age at diagnosis, menopause, tumor histology from two large obstetrical gynecological hospitals China were analyzed.The median diagnosis was 50 years. Fifty-eight percent diagnosed Fifty-six...
Abstract The involvement of hormonal factors in developing endometrial cancer is well documented. In particular, excess or unopposed estrogen a major risk factor. Endometrial divided into estrogen-dependent and estrogen-independent types. Studies suggested that the subtypes share many common factors. Whether levels sex hormones differ between types 1 2 has not been investigated. this study, estrogen, progesterone, testosterone, follicle stimulating hormone (FSH) luteinizing (LH) were...
Objective Endometriosis is considered as a serious gynaecological disease in women at reproductive age. Lower body mass index (BMI) thought to be risk factor. However, recent studies indicated that with normal BMI were also more likely develop endometriosis, suggesting the association controversial. We therefore investigated of and surgically diagnosed endometriosis cohort Chinese women. Design Retrospective case–control study. Setting Tertiary hospital. Patients 709 807 age matched controls...
Gastric carcinoma (GC) remains a significant therapeutic challenge, garnering widespread attention. Oxymatrine (OMT), an active component of the traditional Chinese medicine compound Kushen injection (CKI), has shown promising results in combination with chemotherapy for treatment GC. However, molecular mechanisms underlying OMT's effects GC have yet to be elucidated.
The incidence of ovarian cancer depends on the ethnicity and geographical area. Menopausal status is a well-known risk factor for most cases occur after menopause in Caucasians. However, it less clear how or age at diagnosis associated with including its subtypes Chinese women. Data 1,283 women primary malignant borderline diagnosis, histology from largest women's hospital China was analysed. median 53, 44 23 years epithelial sex-cord tumors germ cell respectively. 58% cancers were diagnosed...
Obesity is a well-known risk factor for developing endometrial cancer. However, the incidence and survival rate of cancer are associated with ethnicity geographical area. In addition, whether menopausal status in obese women obesity subtypes have not been fully investigated. Here, we investigated effect BMI on Chinese taking into account subtypes.Data 1,127 including body mass index (BMI), age at diagnosis, parity, subtype were collected from largest obstetrics & gynaecology hospital China...
Caesarean section rates have significantly increased worldwide. China has a caesarean rate of 46%, with moderate contribution on maternal request. In this study, we investigated the association between characteristics, attendance at prenatal education course and request.Questionnaire study.Tertiary hospital in China.564 questionnaires.On postpartum day 42, questionnaire data were collected. Data including age, parity, gravida, delivery mode, educational level, residence status, living...
Objective: Obesity is one of the common risk factors for developing endometrial cancer and negatively associated with its survival, although this result controversial.Endometrial stages range from stage I, which has better clinical outcomes to IV, poorer outcomes.Endometrial traditionally divides into type 1 2 dependent on histology different outcomes.In study we investigated whether obesity taking account subtypes menopausal status.Methods: Data 1,104 women were retrospectively collected...
Compound Kushen injection (CKI) is a representative medication of Chinese herbal and often used in the adjuvant treatment nasopharyngeal carcinoma (NPC), but its antitumor mechanism poorly understood.To preliminarily elucidate effects possible mechanisms CKI on NPC.In this work, we explored molecular against NPC by using network pharmacology docking. In addition, proteomics was to explore localization quantitative information protein C666-1 cells after intervention CKI, enrichment analysis...