A5101519322- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Gestational Diabetes Research and Management
- Endometrial and Cervical Cancer Treatments
- Distributed Control Multi-Agent Systems
- Neonatal Respiratory Health Research
- Neural Networks Stability and Synchronization
- CAR-T cell therapy research
- Ovarian cancer diagnosis and treatment
- Gestational Trophoblastic Disease Studies
- Uterine Myomas and Treatments
- Cancer Immunotherapy and Biomarkers
- Immunotherapy and Immune Responses
- Reproductive System and Pregnancy
- Cancer-related molecular mechanisms research
- Maternal and fetal healthcare
- Cerebrovascular and genetic disorders
- Viral Infectious Diseases and Gene Expression in Insects
- Gout, Hyperuricemia, Uric Acid
- Biological and pharmacological studies of plants
- Redox biology and oxidative stress
- Calcium signaling and nucleotide metabolism
- Retinal Imaging and Analysis
- Mitochondrial Function and Pathology
- Coenzyme Q10 studies and effects
Second Affiliated Hospital of Xi'an Jiaotong University
2011-2022
Huazhong University of Science and Technology
2010-2021
Tongji Hospital
2021
Kunming Medical University
2018-2021
Children's Hospital of Zhejiang University
2021
Beijing Friendship Hospital
2021
Capital Medical University
2021
First Affiliated Hospital of Kunming Medical University
2018-2021
University of Auckland
2013-2017
Nanjing Drum Tower Hospital
2017
The weighted average prediction (WAP) is introduced into the existing consensus protocol to simultaneously improve robustness communication delay and convergence speed of achieving consensus. It proved that for a supercritical-delay multi-agent system, introducing WAP can not only against but also speed, provided length chosen properly. implementation WAP-based investigated simulations are demonstrate effectiveness theoretical results.
Preeclampsia is triggered by an as yet unknown toxin from the placenta. Antiphospholipid antibodies (aPL), a strong risk factor for preeclampsia, have been shown to induce production of toxic trophoblastic debris High mobility group box 1 (HMGB1) proinflammatory danger signal, and expression it has reported be increased in preeclampsia. This study examined whether aPL or preeclamptic sera increase HMGB1 syncytiotrophoblast debris. Trophoblastic normal placental explants that had cultured...
The incidence of endometrial cancer depends in part on the ethnicity and geographical area which woman resides. Menopause status is a well-known risk factor for most cases occur after menopause. It is, however, less clear how menopause associated with including its subtypes Chinese women.Data 1,746 women age at diagnosis, menopause, tumor histology from two large obstetrical gynecological hospitals China were analyzed.The median diagnosis was 50 years. Fifty-eight percent diagnosed Fifty-six...
Abstract The involvement of hormonal factors in developing endometrial cancer is well documented. In particular, excess or unopposed estrogen a major risk factor. Endometrial divided into estrogen-dependent and estrogen-independent types. Studies suggested that the subtypes share many common factors. Whether levels sex hormones differ between types 1 2 has not been investigated. this study, estrogen, progesterone, testosterone, follicle stimulating hormone (FSH) luteinizing (LH) were...
To profile the small RNA cargo carried by trophoblast debris derived from placenta during normal and preeclamptic pregnancies to determine whether can deliver its RNAs endothelial cells with functional consequences. We confirmed that contents recipient co-culture. Next generation sequencing was employed in both normotensive debris. identified 1278 mature miRNAs 2646 non-miRNA fragments contained. Differential expression analysis 16 (including miR-145), 5 tRNA 3 different tRNAs, 13 snRNA 85...
Abstract The mechanisms by which the fetus induces maternal physiological adaptations to pregnancy are unclear. Cellular debris, shed from placental syncytiotrophoblast into blood and phagocytosed endothelial immune cells, may be one of these mechanisms. Here we show that trophoblastic debris normal first trimester placentae changes in transcriptome proteome cells vitro , might contribute adaptation cardiovascular system pregnancy. Trophoblastic also induced transcribe placenta-specific...
The consensus problems of multi-agents with time-varying delays and switching topologies are studied. First, assume that an agent receives state information from its neighbors fixed communication processes own self-delay respectively. time-delay feedback is introduced into the existing protocol to begenerate improved protocol. Then a sufficient condition derived which can make system self-delays achieve consensus. On this basis, specific form equilibrium influenced by initial states agents,...
Breast cancer is the most common in women worldwide. Studies have shown that high temperature requirement factor A3 (HtrA3) involved important physiological processes including maintenance of mitochondrial homeostasis, cell death, and signaling. HtrA3 reported to be downregulated several cancers has been correlated with advancing stage. We performed a retrospective study using our breast tissue bank investigate whether expression lymphatic metastasis was estrogen receptor (ER) progesterone...
Ovarian cancer is the leading cause of death in gynaecological cancers. The high temperature requirement factor A3 (HtrA3) involved pathogenesis ovarian cancer. In this study we investigated whetherHtrA3 protein levels were altered subtypes and whether HtrA3 down-regulation was associated with peritoneal metastasis. tissues from 89 patients analyzed by immunohistochemistry. lower all lowest epithelial not correlated metastasis
Ovarian cancer is a common gynecological cancer, and parity negatively associated with the incidence of this disease. This negative association hypothesized to be due in part shifting balance estrogen progesterone toward more reduced ovulation during pregnancy. However, studies suggested that also estrogen-independent cancers suggesting hormones may not only protective factor. Extracellular vesicles (EVs) play an important role cell-to-cell communication physiological pathological...
Abstract Background Subacute thyroiditis (SAT) is the most common cause of thyroid pain. Several clinical guidelines recommend that patients who fail to respond full doses non-steroidal anti-inflammatory drugs (NSAIDs) should be treated instead with oral corticosteroid therapy. However, albeit strong recommendations, treatment protocol based on low-quality evidence and high-quality trials are lacking respect optimal initiation dosage usage corticosteroid. We aimed evaluate whether 15 mg/day...
Myelodysplastic syndrome (MDS) is a clonal disease of the elderly characterized by chronic cytopenia, dysplasia, and high risk progression to acute myeloid leukemia (AML). Up until now, few animal models that fully recapitulate clinical features this have been available.This study aimed establish new MDS xenograft model utilizing human MDS-derived cell line with heterozygous Y641C mutation EZH2 (SKM-1). 1 x 107 SKM-1 cells were inoculated into anti-mouse CD122 monoantibody conditioned...
In this paper, we study the multi-agent system to achieve a faster consensus with multiple time-delays under directed asymmetric information exchange topology. We first assume that an agent processes its own state self-delay and receives from neighbors communication delays. Based on proportion derivative feedback, improved protocol can accelerate consensus. A sufficient condition for reaching is then derived based Nyquist stability criterion frequency domain analysis. addition, specific form...
This paper deals with the consensus problem under communication network inducing delays. It has come to light that introducing a delay will lead in general reduction of performance or instability. Therefore, investigating control protocols for time-delay systems converging is important. In present paper, we assume each agent receives its own state information constant and from neighbors different delays respectively. A new protocol by self-PD item proposed. Then sufficient condition based on...