A5100401362- Photoacoustic and Ultrasonic Imaging
- Advanced Sensor and Control Systems
- Optical Imaging and Spectroscopy Techniques
- Analytical chemistry methods development
- Advanced Chemical Sensor Technologies
- Facial Nerve Paralysis Treatment and Research
- Synthesis and properties of polymers
- Dermatologic Treatments and Research
- Cell Image Analysis Techniques
- Medical Imaging Techniques and Applications
- Epigenetics and DNA Methylation
- Nonmelanoma Skin Cancer Studies
- Cerebrovascular and genetic disorders
- Nanoplatforms for cancer theranostics
- Chronic Lymphocytic Leukemia Research
- Insect-Plant Interactions and Control
- Innovation Policy and R&D
- Insect and Pesticide Research
- Plant and animal studies
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Salivary Gland Disorders and Functions
- Immunotherapy and Immune Responses
- Immune cells in cancer
- Wireless Sensor Networks and IoT
- Extracellular vesicles in disease
Wuhan No.1 Hospital
2019-2025
Sichuan University
2022-2025
University of Hong Kong - Shenzhen Hospital
2024
University of Hong Kong
2024
Beijing Forestry University
2024
State Key Laboratory of Tree Genetics and Breeding
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Hebei Provincial Center for Disease Control and Prevention
2021-2024
Chinese People's Liberation Army
2022-2024
Nanjing Medical University
2022-2024
Currently, the commercial separator (Celgard2500) of lithium-ion batteries (LIBs) suffers from poor electrolyte affinity, mechanical property and thermal stability, which seriously affect electrochemical performances safety LIBs. Here, composite separators named PVDF-HFP/TiN for high-safety LIBs are synthesized. The integration PVDF-HFP TiN forms porous structure with a uniform rich organic framework. significantly improves adsorption between electrolyte, causing higher absorption rate...
AimThe aim of the study was to assess patient preference for fixed-dose combination pertuzumab and trastuzumab subcutaneous injection (PH FDC SC) in patients with HER2-positive early breast cancer PHranceSCa (NCT03674112).Materials methodsPatients who completed neoadjuvant P + H chemotherapy surgery were randomised 1:1 three intravenous (IV) cycles followed by PH SC or vice versa (crossover) then chose (SC) IV infusion continue up 18 (continuation). Assessments via healthcare professional...
Introduction The study aimed to explore the association of serum 25(OH)D 3 and hepatic steatosis in non-alcoholic fatty liver disease (NAFLD) patients determine whether effect vitamin D (VD) is mediated by activation peroxisome proliferator-activated receptor α (PPARα) pathway. Methods contained a case-control study, vivo vitro experiments. A was conducted compare parameters between NAFLD controls evaluate NAFLD. In male Wistar rats were randomly divided into control model groups, fed...
Type I interferon (IFN) inhibits a wide spectrum of viruses through stimulating the expression antiviral proteins. As an IFN-induced protein, myxovirus resistance B (MXB) protein was reported to inhibit multiple highly pathogenic human viruses. It remains be determined whether MXB employs common mechanism restrict different Here, we find that IFN alters subcellular localization hundreds host proteins, and this effect is partially lost upon depletion. The results our mechanistic study reveal...
PurposeFHTR2163 is a novel antigen-binding fragment (Fab) directed against high-temperature requirement protein A1 (HtrA1). HTRA1 inhibition may preserve retinal integrity and slow disease progression in geographic atrophy (GA) secondary to age-related macular degeneration (AMD). This study examined the safety, pharmacokinetics, immunogenicity, changes HTRA1-specific substrate Dickkop-related 3 (DKK3) patients with GA who received FHTR2163.DesignPhase I, open-label, single ascending dose...
Abstract Background Pancreatic cancer remains among the most prevalent and aggressive forms of cancer. While immunotherapeutic treatment strategies have shown some promise in affected patients, benefits these interventions been limited by insufficient tumor infiltration activated T cells. Results Here, Titanium diselenide (TiSe 2 ) nanosheets were synthesized with good stability. When exposed to ultrasound (US), TiSe served as a reliable nano-sensitizer capable inducing large amounts...
Abstract Telitacicept, an injectable recombinant human B‐lymphocyte stimulating factor receptor‐antibody fusion protein, is a new dual B lymphocyte stimulator (BLyS)/APRIL (a proliferation‐inducing ligand) inhibitor that effectively blocks proliferation of lymphocytes. This study evaluates the pharmacokinetic characteristics, tolerability, and safety single subcutaneous injection various doses (80, 160, 240 mg) telitacicept in healthy Chinese subjects. trial single‐center, randomized,...
Background The relationship between human serum albumin levels and the prognosis of critical care patients with chronic obstructive pulmonary disease (COPD) remains controversial. Objective To investigate in-hospital mortality in COPD. METHODS: This study used a retrospective observational cohort from Medical Information Intensive Care database (MIMIC-IV) United States. Multivariate Cox regression analysis was to assess mortality. A restricted cubic spline line also explore nonlinear...
Current research does not fully elucidate the key compounds and their mechanisms that define aroma profile of fresh jujube fruits. Therefore, this study conducted a comprehensive analysis both free glycosidically bound in fruits ten cultivars. Utilizing gas chromatography–mass spectrometry (GC-MS), we identified 76 volatile 19 compounds, with esters, aldehydes, ketones emerging as predominant Odor activity value (OAV) revealed primary jujubes is characterized by fruity fatty odors,...
Objective: Neutrophil extracellular traps (NETs) can trigger pathological changes in vascular cells or vessel wall components, which are of hypertension. Therefore, we hypothesized that NETs would be associated with the occurrence Methods: To evaluate relationship between and hypertension, evaluated both formation spontaneously hypertensive rats (SHRs) blood pressure mice injected phorbol-12-myristate-13-acetate (PMA) via tail vein to induce arterial wall. Meanwhile, proliferation cell cycle...
Magnesium (Mg) plays a crucial role in crop growth, but how Mg supply level affects root growth and nutrient absorption vegetable crops with different genotypes has not been sufficiently investigated. In this study, the responses of tomato (Solanum lycopersicum L.) cucumber (Cucumis sativus to levels were explored. Four treatment (i.e., 0.2, 1.0, 2.0, 3.0 mmol/L) applied under hydroponic conditions, denoted as Mg0.2, Mg1, Mg2, Mg3, respectively. The results showed that increasing levels,...
The construction industry has high accident rates, and workers' unsafe behavior is regarded as a major factor resulting in accidents. Behavioral psychology posits that human driven by psychology, personality one of the important psychological characteristics affecting behavior. However, there lack systematic research on relationship between workers. This explored preliminary type unsafety workers, analyzed differences safety performance from perspective types. Myers-Briggs Type Indicator...
Three-dimensional visualization of medical image data can enable doctors to observe images from more angles and higher dimensions. It is great significance for assist in diagnosis preoperative planning. Most 3D systems are based on desktop applications, which too dependent hardware operating system. This makes it difficult use across platforms maintain. Web-based tend have limited capabilities. To this end, we developed a web application, not only provides DICOM (Digital Imaging...
BACKGROUND: Dexmedetomidine, propofol, and midazolam are commonly used sedative-hypnotic drugs. Using a steady-state method, we examined the CO2 ventilatory response, mean arterial blood pressure (MAP) heart rate (HR) effects of these three drugs in sevoflurane-anesthetized rabbits. METHODS: New Zealand white rabbits weighing 2.9 ± 0.2 kg (mean sd) were used. After anesthetic induction tracheostomy, animals inhaled 2% sevoflurane to ensure stable level sedation throughout experiment....