A5033690906- Per- and polyfluoroalkyl substances research
- Effects and risks of endocrine disrupting chemicals
- Quinazolinone synthesis and applications
- Birth, Development, and Health
- Hormonal Regulation and Hypertension
- Sperm and Testicular Function
- Estrogen and related hormone effects
- COVID-19 Clinical Research Studies
- Sexual Differentiation and Disorders
- Respiratory viral infections research
- Neonatal Respiratory Health Research
- Hormonal and reproductive studies
- Asthma and respiratory diseases
- Catalytic C–H Functionalization Methods
- Gestational Diabetes Research and Management
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Phenothiazines and Benzothiazines Synthesis and Activities
- Multicomponent Synthesis of Heterocycles
- Crystallization and Solubility Studies
- Click Chemistry and Applications
- Synthesis and Characterization of Heterocyclic Compounds
- Advanced Synthetic Organic Chemistry
- Lung Cancer Diagnosis and Treatment
- Synthesis and biological activity
- SARS-CoV-2 and COVID-19 Research
Peking University First Hospital
2019-2025
Anqing City Hospital
2025
Anhui Medical University
2015-2025
Dongguan People’s Hospital
2025
Peking University
2019-2024
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2013-2022
Wenzhou Medical University
2012-2022
Pulmonary Associates
2017
Wenzhou University
2014-2016
First Affiliated Hospital of Anhui Medical University
2015
Abstract This paper retrospectively analysed the prevalence of macrolide-resistant Mycoplasma pneumoniae (MRMP) in some parts China. Between January 2013 and December 2019, we collected 4,145 respiratory samples, including pharyngeal swabs alveolar lavage fluid. The highest PCR-positive rate M. was 74.5% Beijing, resistance 100% Shanghai, Gansu lowest with 20%. 2013, MRMP 97.4% 2019; for adults Beijing 17.9% 10.48%. Among children diagnosed community-acquired pneumonia (CAP), rates were both...
The cytological diagnostic process of EUS-FNA smears is time-consuming and manpower-intensive, the conclusion could be subjective controversial. Moreover, relative lack cytopathologists has limited widespread implementation Rapid on-site evaluation (ROSE) presently. Therefore, this study aimed to establish an AI system for detection pancreatic ductal adenocarcinoma (PDAC) based on images. We collected 3213 unified magnification images cell clusters from 210 mass patients who underwent in...
A palladium-catalyzed direct addition of arylboronic acids to unprotected 2-aminobenzonitriles has been developed, leading a wide range 2-aminobenzophenones with moderate excellent yields. The transformation broad scope and high functional group tolerance. Moreover, 2-oxoindoline-7-carbonitrile indole-7-carbonitrile were applicable this process for the construction 7-benzoyl-2-oxoindolines 7-benzoylindoles, respectively. Among compounds examined, compound 4e possessed most potent anticancer...
Placenta secretes a large amount of progesterone and estradiol, which are critical for maintaining pregnancy. In human placenta, 3β-hydroxysteroid dehydrogenase 1 (HSD3B1) catalyzes pregnenolone to form progesterone, aromatase (CYP19A1) testosterone into estradiol. Fungicides display antifungal activities widely used prevent fungal infections in agricultural plants. These chemicals include azoles, such as tebuconazole (TEB), triadimefon (TRI), vinclozolin (VCZ) or organotins, tributyltin...
Energy metabolism disorder is a critical process in lung ischemia–reperfusion injury (LIRI). This study was aimed to determine the effects of resolvin D1 (RvD1) on energy LIRI. Forty Sprague–Dawley rats were divided into following groups: Sham group; untreated (IR) control; IR treated with normal saline (IR-NS); and RvD1 (IR-RV) (100 μg/kg, iv). LIRI determined these rats. The results revealed that levels interleukin (IL)-1β, tumor necrosis factor-α, IL-10, monocyte chemoattractant...
Abstract Perfluorooctane sulfonate (PFOS) is widely used in industry and consumer products. Previous studies have showed that PFOS gestational exposure associated with offspring lung damage rat. However, the underlying mechanisms remain poorly understood. In this study, we investigated role of gasdermin E (GSDME) injury its using vivo vitro approaches. Pregnant SD rats were exposed to (1 mg/kg BW/d) between day 12–18, tissue was evaluated on postnatal 7. treated animals exhibited alveolar...