A5064197888- Lymphoma Diagnosis and Treatment
- Sarcoidosis and Beryllium Toxicity Research
- Medical Imaging and Pathology Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Fault Detection and Control Systems
- Lung Cancer Treatments and Mutations
- Pleural and Pulmonary Diseases
- Radiomics and Machine Learning in Medical Imaging
- Gastric Cancer Management and Outcomes
- Genetic factors in colorectal cancer
- RNA modifications and cancer
- Metastasis and carcinoma case studies
- Viral-associated cancers and disorders
- Spondyloarthritis Studies and Treatments
- Chronic Myeloid Leukemia Treatments
- Single-cell and spatial transcriptomics
- Neuroblastoma Research and Treatments
- Phagocytosis and Immune Regulation
- Virus-based gene therapy research
- Digestive system and related health
- Meningioma and schwannoma management
- Occupational exposure and asthma
- Congenital Diaphragmatic Hernia Studies
- AI in cancer detection
- Tracheal and airway disorders
Universidade Federal do Rio de Janeiro
2024
University of Siena
1995-2022
Azienda Ospedaliera Universitaria Senese
2022
The role of HPV in the carcinogenesis intraepithelial and invasive anogenital lesions is currently well established. E6 E7 oncoproteins high risk genotypes are known to inactivate p53 pRb pathways. Several studies have described an increased prevalence recurrence both cervical infection cancer among HIV-1 positive women compared negative cases. For these reasons, considered AIDS-defining neoplasm. Unlike other AIDS-associated neoplasms, occurrence independent immune suppression. patients...
Fault detection constitutes a fundamental task for predictive maintenance, requiring mathematical models that can be conveniently provided by data-driven techniques. Autoencoders are particular type of unsupervised Artificial Neural Networks suitable fault applications. Diverse architectures might used autoencoders, resulting in different performances, which usually compared means Detection Rates fixed threshold the False Alarm Rate, limiting conclusions to cases. To improve comparability,...
This paper introduces BibMon, a Python package that provides predictive models for data-driven fault detection and diagnosis, soft sensing, process condition monitoring. Key features include regression reconstruction models, preprocessing pipelines, alarms, visualization through control charts diagnostic maps. BibMon also includes real simulated datasets benchmarking, comparative performance analysis of different hyperparameter tuning. The is designed to be highly extensible, allowing easy...
Gastric dysplasia (high-grade, HGD, and low-grade, LGD) normal mucosa were tested for anti-p53, anti-Ki-67 anti-PCNA monoclonal antibodies on paraffin sections, relative AgNOR area number semithin Epon-Araldite sections. The proliferative compartment in was restricted to the middle layer corresponding neck-isthmus region. In LGD HGD there an expansion of this lower upper layers mucosa, particular layer. p53 always negative as well while it positive 34 out 51 cases HGD. most discriminant...
Angiogenic switch marks the beginning of tumor's strategy to acquire independent blood supply. In some subtypes non-Hodgkin's lymphomas, higher local vascular endothelial growth factor (VEGF) expression correlates with increased microvessel density. However, this VEGF is only in tumors elevated receptors factor, suggesting an autocrine growth-promoting feedback loop. Several studies have indicated that are also targeted by Tat protein from HIV-1-infected cells. Given similarity basic region...
Background and aims: Although the management of thymomas has been extensively evaluated, value prognostic factors in outcome these patients remains unclear. Methods results: The medical records all who underwent resection thymoma between January 1985 September 2010 at a single thoracic unit were reviewed. Patients followed up with reference to disease recurrence development additional malignancies (AM). Total thymectomy was performed 68 cases. Mean follow-up time four years. survival 63.9...
Pleuroparenchymal fibroelastosis (PPFE) is a rare interstitial lung disease characterized by the fibrotic thickening of subpleural and parenchymal areas upper lobes. It may be both idiopathic or secondary to infections, diseases and/or drug exposure. Often PPFE patients report recurrent lower respiratory tract suggesting that repeated inflammatory alterations induced pulmonary infections contribute development/progression PPFE. Here, we for first time case patient affected Giant cell...
"Histology of the synovial membrane patients affected by osteoarthritis and calcium pyrophosphate dihydrate crystal deposition disease vs. alone: a pilot study." Scandinavian Journal Rheumatology, 45(6), pp. 538–539
Coarse granularity of nuclear chromatin texture is a prominent feature most malignant cell lines. We have chosen the abrupt transition from eu- to heterochromatic foci (high contrast gradient [CG]) as novel parameter for coarseness. This was quantified using automated image analysis single nuclei in smears stained by May-Grünwald-Giemsa technique. The principle this approach consists eliminating, with help subtraction between two lowpass filters, small grey level differences among pixels, so...
Early gastric cancers (EGC) may be subdivided into 2 groups by means of the use mitotic index, apoptotic index and cell density: EGCs with high turnover low density, which show dissociation and, more frequently, lymph node invasion; density. The same parameters discriminate among intestinal type tumors, when separately considered from diffuse ones. No correlation is noted these transforming growth factor-alpha, epidermal factor receptor p53 expression, gross type, entity neoangiogenesis,...