A5021427821- Lymphoma Diagnosis and Treatment
- Cervical Cancer and HPV Research
- Lung Cancer Treatments and Mutations
- Immunotherapy and Immune Responses
- Cancer-related Molecular Pathways
- Chronic Lymphocytic Leukemia Research
- Hepatitis B Virus Studies
- Cancer Immunotherapy and Biomarkers
- Mast cells and histamine
- Medical Imaging and Pathology Studies
- Skin and Cellular Biology Research
- Molecular Biology Techniques and Applications
- Viral-associated cancers and disorders
- Cancer Cells and Metastasis
- Reproductive tract infections research
- Breast Cancer Treatment Studies
- Genital Health and Disease
- Salivary Gland Tumors Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
- Herpesvirus Infections and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cutaneous lymphoproliferative disorders research
- Atherosclerosis and Cardiovascular Diseases
- Oral and Maxillofacial Pathology
- RNA Research and Splicing
University of Milano-Bicocca
2023
University of Insubria
2023
University of Siena
1997-2011
Russian Cancer Research Center NN Blokhin
2011
Russian Medical Academy of Continuous Professional Education
2006
Azienda Ospedaliero-Universitaria Careggi
1997
Istituto Oncologico Romagnolo
1989
Cancer Society of Finland
1988
University of Pavia
1979
The molecular feature of Burkitt lymphoma (BL) is the translocation that places c-Myc under control immunoglobulin gene regulatory elements. However, there accumulating evidence some cases may lack an identifiable MYC translocation. In addition, during EUROFISH project, aiming at standardization FISH procedures in diagnosis, we found five out 35 classic endemic BLs were negative for translocations by using a split-signal as well dual-fusion probe. Here investigated expression pattern miRNAs...
Background: Integration of human papillomavirus (HPV) DNA has been considered a late event in cervical carcinogenesis. However, integrated forms HPV were recently detected cancer precursor lesions using new real time polymerase chain reaction (PCR) to detect the deletions at 3362–3443 region HPV16 E2 Objective: To study frequency integration and compare sensitivity an additional upstream ORF (2962–3138) detecting integration. Methods: Using TaqMan based PCR, positive samples analysed 164...
ABSTRACT The recognition of high-risk human papillomaviruses (HPVs) as etiological agents cervical cancer has increased the demands to use testing for HPV detection abnormal smears and screening. present study compared performance Hybrid Capture 2 (HC2) assay with that PCR significant lesions in 1,511 women different risks infections three New Independent States former Soviet Union. results showed level agreement between HC2 was substantial, a kappa (Cohen) value 0.669 (95% confidence...
The human uterine mucosa of early pregnancy is largely populated by CD56(bright) natural killer (NK) cells (uterine (u) NK cells). specific functions these are still unknown, but their interaction and response to foetal trophoblasts thought be important for the establishment a successful pregnancy. study reported herein shows that uNK respond to, produce, macrophage migration inhibitory factor (MIF), cytokine highly expressed in placenta cyclic pregnant endometrium. Recombinant MIF reduced...
Recently, conflicting results on human papillomavirus (HPV) clearance have been reported and the data accumulation of incident HPV infections are still fragmentary. Thus, we completed an analysis age-specific incidence rates high-risk (HR) infectionsin 448 women participating in a multi-centre screening study three New Independent States countries. At baseline, 239 were negative for HR DNA, whereas 209 HPV-positive cleared during prospective follow-up. The cumulative clearanceof modelled...
Several studies have investigated the expression of cytokeratins (CKs), vimentin, epithelial growth factor receptor (EGFR), oestrogen (ER), and progesterone (PgR), in breast cancer, but no study has directly compared p53 mutations with these phenotypic differentiation markers same case. The present was designed to provide some this information.The bcl-2 proteins evaluated by immunohistochemistry relation characteristics cellular kinetic parameters (mitotic index apoptotic index) 37 cases...
The origin and function of monocytoid B cells (MBCs) are poorly understood. Taking advantage their strong expression IRTA1 (a receptor that is also associated with MALT marginal zone cells), we have comprehensively analysed MBCs in 25 cases lymphadenitis different aetiologies, shedding new light on the topographical distribution, immunophenotype IgVH gene usage mutational profile this cell subset. IRTA1+ MBCs, although predominantly located subcapsular intermediary sinuses, were observed...
The survival rates of 90 patients who underwent operation for bronchogenic carcinoma were analyzed statistically according to sex, age, tumor stage and histologic type, types surgical procedures (lobectomy or pneumonectomy), immunomorphologic parameters immnologic activity in peribronchial hilar lymph nodes. Stage I group survived significantly longer than did the II III groups, lobectomized pneumonectomized patients. absence presence node metastases was one major determinants survival. mean...
In the present study histologic, clinical and follow-up data of 37 cases retinoblastoma were statistically analyzed by means a multivariate method. The evaluated histological parameters were: growth pattern, degree differentiation, number mitoses, presence necrosis, pseudorosettes, blood vessel basophilia, calcification, extension to anterior chamber, invasion optic nerve ocular coats (choroid sclera). analysis was based upon Cox proportional hazards regression model. Invasion proved be...
OBJECTIVE: Activin A is a multifunctional growth and cell differentiation factor produced by normal endometrium, secreted in high amounts endometrial adenocarcinoma. In the present study we evaluated expression of two inhibitory activin ligands, follistatin follistatin-related gene (FLRG), adenocarcinoma age-matched healthy human endometrium. DESIGN AND METHODS: Atropic menopausal (n=13) tumoral (n=9 adenocarcinoma) tissues were processed to evaluate mRNA levels (by semiquantitative RT-PCR)...