A5047486884- Leprosy Research and Treatment
- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Infectious Diseases and Tuberculosis
- Chronic Lymphocytic Leukemia Research
- Hematological disorders and diagnostics
- Blood groups and transfusion
- Hepatitis B Virus Studies
- Pharmacological Effects of Natural Compounds
- Antibiotic Resistance in Bacteria
- Dermatoglyphics and Human Traits
- Immunotherapy and Immune Responses
- Immunodeficiency and Autoimmune Disorders
- Herpesvirus Infections and Treatments
- Psoriasis: Treatment and Pathogenesis
- Neutropenia and Cancer Infections
- Bacteriophages and microbial interactions
- DNA Repair Mechanisms
- Acne and Rosacea Treatments and Effects
- Drug-Induced Adverse Reactions
- Peripheral Neuropathies and Disorders
- Pharmacological Effects and Toxicity Studies
- CRISPR and Genetic Engineering
- Medical and Biological Sciences
- Polymer-Based Agricultural Enhancements
University of Florida
2024
National JALMA Institute for Leprosy & Other Mycobacterial Diseases
1997-2019
Indian Council of Medical Research
1996-2015
Government of India
2008
Ministry of Health and Family Welfare
2008
Sarojini Naidu Medical College
2005
Medical Research Council
1999
Northwick Park Hospital
1999
Hammersmith Hospital
1999
National Institute of Immunology
1999
The global food supply heavily depends on utilizing fertilizers to meet production goals. adverse impacts of traditional fertilization practices the environment have necessitated exploration new alternatives in form smart fertilizer technologies (SFTs). This review seeks categorize SFTs, which are slow and controlled-release Fertilizers (SCRFs), nano fertilizers, biological describes their operational principles. It examines environmental implications conventional outlines attributes SFTs...
Abstract There is a great range in outcomes after mycobacterial infections, and this probably due to individual variation immune responses. One of the key cytokine regulators response interleukin (IL‐) 12. The IL12B gene encodes p40 chain both IL‐12 IL‐23 it has two major variant sites at which different alleles are associated with increased levels expression susceptibility immune‐related diseases. We hypothesized that variants would be as persistent infection. tested hypothesis by...
Summary Objective To describe the rationale, design and preliminary results of an open trial 6 months uniform multi‐drug therapy (U‐MDT) for all types leprosy patients assuming a cumulative relapse rate not exceeding 5% over 5 years follow‐up. Methods We intended to recruit 2500 each in multi‐bacillary (MB) pauci‐bacillary (PB) groups from India (five centres) China (two centres). Standardized clinical criteria were used assess skin lesions field. Results A total 2912 enrolled November 2003...
Setting Community based tuberculosis (TB) prevalence surveys in ten sites across India during 2006–2012 Objective To re-analyze data of recent sub-national using uniform statistical methods and obtain a pooled national level estimate TB. Methods Individuals ≥15 years old were screened by interview for symptoms suggestive Pulmonary TB (PTB) history anti-TB treatment; additional screening chest radiography was undertaken five sites. Two sputum specimens examined smear culture among...
Abstract Several lines of evidence highlight the genetic basis risk to develop mycobacterial diseases. Human leukocyte antigen (HLA)‐DR2 alleles (DRB1*1501 and DRB1*1502) have been found be strongly associated with disease, especially more severe forms such as lepromatous leprosy multidrug‐resistant pulmonary tuberculosis. In this study, DNA‐based high‐resolution typing techniques polymerase chain reaction–sequence‐specific oligonucleotide probe were used determine distribution HLA‐DR/DQ in...
Sixteen strains of cultivable mycobacteria were grown in Sauton’s medium, and Mycobacterium leprae was purified from armadillo liver. Cell extracts prepared log-phase growths each the mycobacterial strains. Superoxide dismutase (SOD) enzyme all included study, antibodies against SOD raised rabbits. Immunological distances (ImDs) between these anti-SOD antigens determined by a previously described immunoprecipitation method recently developed enzyme-linked immunosorbent assay (ELISA)...
Nucleic acid sequences of Mycobacterium leprae were detected using gene probes hybridizing with targeting ribosomal RNA (16S rRNA), DNA rDNA) and amplification techniques (PCR) in skin lesion paediatric leprosy patients the effect treatment on by these methods. Eighty included study. Most cases (79%) between 9 16 years age. Cases divided into three groups according to status, viz. untreated (30), undergoing at end (20). Clinical slit smear examination for fast bacilli (AFB) was performed...