- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Prenatal Screening and Diagnostics
- Neuroscience and Music Perception
- Congenital Anomalies and Fetal Surgery
- Occupational exposure and asthma
- Demographic Trends and Gender Preferences
- Sleep and related disorders
- Genetic Associations and Epidemiology
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Spaceflight effects on biology
- Connective tissue disorders research
- Retinoids in leukemia and cellular processes
- Tissue Engineering and Regenerative Medicine
- Child Nutrition and Feeding Issues
- Genetic Neurodegenerative Diseases
- Ectopic Pregnancy Diagnosis and Management
- Autoimmune and Inflammatory Disorders Research
- Global Cancer Incidence and Screening
- Ion channel regulation and function
- Cellular Mechanics and Interactions
- Chromosomal and Genetic Variations
- Inhalation and Respiratory Drug Delivery
- Cellular transport and secretion
- BRCA gene mutations in cancer
University of Rome Tor Vergata
2013-2021
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2017
Vita-Salute San Raffaele University
2017
Istituti di Ricovero e Cura a Carattere Scientifico
2017
Age-related Macular Degeneration (AMD) represents one of the most sight-threatening diseases in developed countries that substantially impacts patients' lifestyle by compromising everyday activities, such as reading and driving. In this context, understanding prevalence, burden, population-specific risk/protective factors AMD is essential for adequate health care planning provision. Our work aimed to characterize exudative Italian population identify susceptibility/protective (genetic...
In idiopathic pulmonary fibrosis (IPF), lung accumulation of excessive extracellular iron and macrophage haemosiderin may suggest disordered homeostasis leading to recurring microscopic injury fibrosing damage. The current study population comprised 89 consistent IPF patients 107 controls. 54 11 controls underwent bronchoalveolar lavage (BAL). Haemosiderin was assessed by Perls' stain, BAL fluid malondialdehyde (MDA) high-performance liquid chromatography, cell iron-dependent oxygen radical...
(1) Background: The aim of our study is to evaluate whether cell-free DNA testing can overlap the genetic miscarriage tissue in women with early pregnancy loss (EPL) and length recurrent (RPL); (2) Methods: We conducted a prospective cohort at Pregnancy Loss Unit Fondazione Policlinico Universitario A. Gemelli (IRCCS), Rome, Italy between May 2021 March 2022. included EPL RPL. Gestational age was >9 weeks + 2 days <12 0 gestation corresponding crown rump measurement >25 <54 mm. Women...
Background: The identification of women at high risk breast cancer (BC) is crucial for personalized screening strategies. Pathogenic and likely pathogenic variants (PVs/LPVs) in susceptibility genes explain part the individual risk. Moreover, a polygenic background, summarized as score (PRS), contributes to BC may modify carrier non-carrier members families. Methods: We performed retrospective pilot study evaluating PRS from subset high- (BRCA1 BRCA2) moderate-risk (PALB2 ATM) included...
Abstract Background Mechanical unloading in microgravity is thought to induce tissue degeneration by various mechanisms, including the inhibition of regenerative stem cell differentiation. In this work, we investigate effects simulation on early lineage commitment hiPSCs from healthy and Marfan Syndrome (MFS; OMIM #154700) donors, using embryoid bodies model differentiation evaluating their ultra-structural conformation. MFS involves an anomalous organization extracellular matrix for a...
This study extends previous research on the relationship among dream content, waking day mood and anxiety while examining these variables between Italian Canadian participants. One-hundred females from Trent University, Canada (M = 23.4, SD 1.8) 100 Tor Vergata Rome 25.6, 1.9) volunteered one report completed measures of (BAI) disturbance (POMS-SF). Dream imagery was categorized with Hall Van de Castle’s method Content Analysis conducted via computer textual analyses. Significant...
The hypoacusia can be classified in two clinical forms: Syndromic (SHL) and Nonsyndromic (NSHL). In particular, the NSHL describes 70-80% of cases it is mainly due to genetic factors, which are causative deafness at birth. presents different inheritance patterns: autosomal dominant (20%), recessive (80%), X-linked (1%), mitochondrial respectively. To date, about 35 deafness-causative genes have been identified most them codify for connexin transmembrane proteins. Approximately 1:2500...
Introduction Enteroceptive awareness is defined as the ability to perceive body states. Such provided by enteroceptors, organs and structures specifically designated receive both internal external stimuli. This capability, especially perception of satiation, seems be lacking in individuals suffering from Eating Disorders there no procedure increase this ability. Objectives The primary purpose improve patient's enteroceptive awareness. We tested whether patients diagnosed with binge eating...