Lt Marsella

ORCID: 0000-0002-7005-7526
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About
Contact & Profiles
Research Areas
  • Medical Malpractice and Liability Issues
  • Ethics in medical practice
  • Legal and Labor Studies
  • Educational and Social Studies
  • Retinal Diseases and Treatments
  • Patient Dignity and Privacy
  • Digital Imaging in Medicine
  • Restraint-Related Deaths
  • Italian Social Issues and Migration
  • Autopsy Techniques and Outcomes
  • Antioxidant Activity and Oxidative Stress
  • Dermatology and Skin Diseases
  • Healthcare Quality and Management
  • Forensic Toxicology and Drug Analysis
  • Child and Adolescent Health
  • Dental Education, Practice, Research
  • Bioethics and Human Rights Issues
  • Occupational and environmental lung diseases
  • Retinal Imaging and Analysis
  • Healthcare Decision-Making and Restraints
  • Herpesvirus Infections and Treatments
  • Law, AI, and Intellectual Property
  • Forensic and Genetic Research
  • Jury Decision Making Processes
  • Psychedelics and Drug Studies

University of Rome Tor Vergata
2012-2024

Université de Lorraine
2021

Inserm
2021

Luigi Sacco Hospital
2021

University of Milan
2021

University of Verona
2021

University Centre of Legal Medicine
2021

Università Cattolica del Sacro Cuore
2021

University of Geneva
2021

University of Lausanne
2021

Post-herpetic neuralgia is the most challenging and debilitating complication of herpes zoster in immunocompetent host. Because effect treatment disappointing once syndrome has developed, it important to know which factors predict post-herpetic occurrence facilitate selection patients with a higher risk developing undertake preventative strategies. The present study aimed at identifying demographic, clinical psychosocial correlates sample 219 patients, who were examined by dermatologists...

10.1002/jmv.21254 article EN Journal of Medical Virology 2008-07-22

Postprandial oxidative stress is characterized by an increased susceptibility of the organism towards damage after consumption a meal rich in lipids and/or carbohydrates. Micronutrients modulate immune system and exert protective action reducing low density lipoproteins (LDL) oxidation via induction antioxidant enzymes. We evaluated gene expression (HOSp), inflammasome (HIp), human drug metabolism pathways (HDM) ox‐LDL level at baseline intake red wine naturally enriched with resveratrol...

10.1155/2015/317348 article EN cc-by Mediators of Inflammation 2015-01-01

Age-related macular degeneration (AMD) is the main cause of blindness in developed world. The etiology AMD multifactorial due to interaction between genetic and environmental factors. IL-8 has a role inflammation angiogenesis; we report characterization allele architecture evaluate SNPs or haplotypes susceptibility wet AMD, case-control study.Case-control study including 721 patients 660 controls becoming from Italian population. Genotyping was carried out by Real Time-PCR. Differences...

10.1371/journal.pone.0066978 article EN cc-by PLoS ONE 2013-06-19

The important role of food and nutrition in public health is being increasingly recognized as crucial for its potential impact on health-related quality life the economy, both at societal individual levels. prevalence non-communicable diseases calls a reformulation our view food. Hazard Analysis Critical Control Point (HACCP) system, first implemented EU with Directive 43/93/CEE, later replaced by Regulation CE 178/2002 852/2004, internationally agreed approach safety control. Our aim to...

10.1186/s12967-015-0484-2 article EN cc-by Journal of Translational Medicine 2015-04-22

Age-related Macular Degeneration (AMD) represents one of the most sight-threatening diseases in developed countries that substantially impacts patients' lifestyle by compromising everyday activities, such as reading and driving. In this context, understanding prevalence, burden, population-specific risk/protective factors AMD is essential for adequate health care planning provision. Our work aimed to characterize exudative Italian population identify susceptibility/protective (genetic...

10.18632/oncotarget.23241 article EN Oncotarget 2017-12-12

Interest in medical errors has increased during the last few years owing to number of malpractice claims. Reasons for increasing claims may be related patients' higher expectations, iatrogenic injury, and growth legal services industry. Claims analysis provides helpful information specialties which a occur, highlighting areas where orthopaedic care might improved.

10.1007/s11999-013-3165-6 article EN Clinical Orthopaedics and Related Research 2013-07-15

There is recent mounting evidence that nanoparticles may have enhanced toxicological potential in comparison to the same material bulk form. The aim of this study was develop a new method for unmask asbestos nanofibers from Formalin-Fixed, Paraffin-Embedded tissue. an increasing amount enhance Formalin-Fixed (FFPE) For first time, we applied Energy Dispersive X-ray (EDX) microanalysis through transmission electron microscopy demonstrate presence histological specimens patients with possible...

10.4081/ejh.2016.2573 article EN cc-by-nc European Journal of Histochemistry 2016-02-01

Objective . The aim of this study was to validate the role diffusion-weighted imaging (DWI) at 3 Tesla in differential diagnosis between benign and malignant laterocervical lymph nodes patients with head neck squamous cell carcinoma (HNSCC). Materials Methods Before undergoing surgery, 80 patients, biopsy proven HNSCC, underwent a magnetic resonance exam. Sensitivity (Se) specificity (Spe) conventional criteria DWI detecting node metastases were calculated. Histological results from...

10.1155/2014/532095 article EN cc-by BioMed Research International 2014-01-01

Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms were found associated with body mass index (BMI)-defined obesity and lean mass. The aim of our study was to examine the role C677T MTHFR polymorphism in response diet management metabolic syndrome. We investigated composition factor changes after an hysocaloric balanced (HBD), Italian obese women affected by syndrome (MS). Forty four MS eligible for study. A HBD 12 weeks assigned. Study participation included a complete screening...

10.1186/s12967-014-0329-4 article EN cc-by Journal of Translational Medicine 2014-11-28

Abstract The tumour suppressor p53 plays an important role in somatic cell reprogramming. While wild-type reduces reprogramming efficiency, mutant exerts a gain of function activity that leads to increased efficiency. Furthermore, induced pluripotent stem cells expressing lose their pluripotency vivo and form malignant tumours when injected mice. It is therefore great interest identify targets (wild type mutant) are responsible for this phenotype during reprogramming, as these could be...

10.1038/cddis.2016.419 article EN cc-by Cell Death and Disease 2016-12-29

Cocaine use is increasing around the world and its purity frequently altered through dilution, substitution, contamination, adulteration. Sugars, talc, starch, carbonates represent principal diluents of cocaine, while phenacetin, levamisole, caffeine, lidocaine are major adulterants in Europe. Levamisole used because it an odorless powder, with physical properties similar to has reasonable cost availability, being widely veterinary medicine. For this study, we analyzed 88 cocaine samples....

10.1080/02791072.2017.1361558 article EN Journal of Psychoactive Drugs 2017-08-16

Healthcare-associated infections are a major clinical and public health problem that involve, in variety of ways, healthcare professionals, hospital administrators and, above all, patients. In Italy, the incidence infectious complications generally varies from 5-10% (hospitalized patients) to 1% (home care patients); such manifest epidemically, caused by antibiotic-resistant microorganisms becoming more common, with mortality rate 20-30%. Moreover, any "preventable deaths or serious...

10.7416/ai.2015.2073 article EN PubMed 2016-02-03

Background: Age-related macular degeneration (AMD) is the main cause of blindness in developed world.The etiology AMD multifactorial due to interaction between genetic and environmental factors.IL-8 has a role inflammation angiogenesis; we report characterization IL-8 allele architecture evaluate SNPs or haplotypes susceptibility wet AMD, case-control study.Methods: Case-control study including 721 patients 660 controls becoming from Italian population.Genotyping was carried out by Real...

10.1371/annotation/d8311dd7-2499-4ef1-b731-b4830b1612df article EN cc-by PLoS ONE 2013-07-10

Background: Drugged driving is associated with an increased risk of road accidents worldwide. In Italy, under the influence (DUI) alcohol and drugs a reason for disqualification or revocation license. Drivers charged must attend Local Medical Commission (LMC) to undergo mandatory examinations regain suspended Our study mainly aims report on analysis performed hair samples collected from 7560 drivers who had their licenses drugged drunk between January 2019 June 2024. Methods: A rapid,...

10.3390/ph17121728 article EN cc-by Pharmaceuticals 2024-12-20

Worldwide tobacco smoking kills nearly 6 million people each year, including more than 600,000 non-smokers who die from smoke exposure. Environmental (ETS, also called secondhand smoke, involuntary or passive smoke) is the combination of sidestream given off by a burning product and mainstream exhaled smokers. People may be exposed to ETS in homes, cars, workplaces, public places, such as bars, restaurants, recreational settings. In addition, there another type which until now has not been...

10.7417/ct.2013.1623 article EN PubMed 2013-01-01

The neurologic sequelae post-measles are less common than other complications measles-related and can lead to severe disability or death: primary measles encephalitis (PME), acute post-infectious encephalomyelitis (APME), inclusion body (MIBE), subacute sclerosing panencephalitis (SSPE). SSPE syndrome affect people years from the virus infection, as result of persistence defective viral particles in brain cells. Clinical onset typically manifests with progressive intellectual deterioration,...

10.4415/ann_17_02_15 article EN PubMed 2017-06-16

The professional liability of healthcare professionals is a decidedly current issue. In the past decade, litigation for alleged medical malpractice incidents has increased exponentially in Europe. Italy, last 20 years have been witness to significant upheavals this sense. article, we analyse evolution legislation as well addressing, some detail, changes introduced by Law 189/2012, with which Italian legislators radically revolutionized sector. Particular attention dedicated jurisprudential...

10.1163/15718093-12341357 article EN European Journal of Health Law 2015-07-31

Road traffic accidents (RTA) are a serious issue in all industrialized countries and have dramatic social healthcare-related implications. Fatigue (sleepiness) is the principal identifiable preventable cause of road accidents. Obstructive sleep apnoea syndrome (OSAS) narcolepsy two leading causes excessive daytime sleepiness. In this article, authors analyze current Italian legislation regarding driving licence issuance fitness to drive, order evaluate potential implications disorders,...

10.7417/ct.2014.1766 article EN PubMed 2014-01-01
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