A5040373175- Emergency and Acute Care Studies
- Healthcare Policy and Management
- Connective tissue disorders research
- Venous Thromboembolism Diagnosis and Management
- Trauma and Emergency Care Studies
- Radiomics and Machine Learning in Medical Imaging
- Health Systems, Economic Evaluations, Quality of Life
- Aortic Disease and Treatment Approaches
- Ultrasound in Clinical Applications
- Brain Tumor Detection and Classification
- Pharmaceutical Economics and Policy
- Chronic Disease Management Strategies
- BRCA gene mutations in cancer
- Global Cancer Incidence and Screening
- Cardiac Valve Diseases and Treatments
- Genetic factors in colorectal cancer
- AI in cancer detection
- Maternal and fetal healthcare
- Cardiac electrophysiology and arrhythmias
- Maternal and Perinatal Health Interventions
- Galectins and Cancer Biology
- Thyroid Cancer Diagnosis and Treatment
- Genetic Neurodegenerative Diseases
- Child Nutrition and Water Access
- Breastfeeding Practices and Influences
University of Rome Tor Vergata
2006-2024
University Niccolò Cusano
2015-2023
McMaster University
2018-2022
Policlinico Tor Vergata
2015-2021
University of Toronto
2015-2021
William Osler Health System
2018-2020
Islamic Azad University of Shahreza
2020
Vali Asr University of Rafsanjan
2019
Islamic Azad University, Yazd
2019
Brampton Civic Hospital
2017
Abstract The efficacy of breath volatile organic compounds (VOCs) analysis for the screening patients bearing breast cancer lesions has been demonstrated by using gas chromatography and artificial olfactory systems. On other hand, in-vitro studies suggest that VOCs detection could also give important indications regarding molecular tumorigenic characteristics tumor cells. Aim this study was to analyze in headspace cell lines order ascertain potentiality signatures giving information about...
OBJECTIVE: To determine whether there is an association between the total breastfeeding duration and iron stores, deficiency, deficiency anemia in healthy urban children. METHODS: A cross-sectional study of children, aged 1 to 6 years, seen for primary health care December 2008 July 2011 was conducted through TARGet Kids! practice-based research network. Univariate adjusted regression analyses were used evaluate serum ferritin, anemia. RESULTS: Included 1647 children (median age 36 months)...
Myotonic dystrophy type 1 (DM1) is a multisystem disorder that affects skeletal and smooth muscle as well the eye, heart, endocrine system, central nervous system. DM1 caused by expansion of CTG trinucleotidedaggerrepeat in gene DMPK. Clinical findings span continuum from mild to severe. Although repeat correlates with disease phenotype, caution used predicting severity on basis number. This study reports an extensive genotype-phenotype evaluate clinical validity utility molecular genetic...
Breast lesion segmentation in magnetic resonance (MR) images is one of the most important parts clinical diagnostic tools. Pixel classification methods have been frequently used image with two supervised and unsupervised approaches up to now. Supervised lead high accuracy, but they need a large amount labeled data, which hard, expensive, slow be obtained. On other hand, no prior knowledge low performance. However, semi-supervised learning uses not only few also unlabeled data promises higher...
To describe selected anthropometric and health status variables among immigrant refugee children ≤6 years of age within an inner city clinic in Toronto, Ontario. A retrospective chart review patients born between January 1, 1998 December 31, 2008, was conducted at a Toronto community centre serving primarily population. Outcome measures included calculated age-specific percentiles for height weight, the prevalence anemia, iron deficiency, enteric parasites, elevated lead levels, HIV...
Background: The identification of women at high risk breast cancer (BC) is crucial for personalized screening strategies. Pathogenic and likely pathogenic variants (PVs/LPVs) in susceptibility genes explain part the individual risk. Moreover, a polygenic background, summarized as score (PRS), contributes to BC may modify carrier non-carrier members families. Methods: We performed retrospective pilot study evaluating PRS from subset high- (BRCA1 BRCA2) moderate-risk (PALB2 ATM) included...
Oculo-auriculo-vertebral spectrum (OAVS) is a developmental disorder of craniofacial morphogenesis. Its etiology unclear, but assumed to be complex and heterogeneous, with contribution both genetic environmental factors. We assessed the occurrence copy number variants (CNVs) in cohort 19 unrelated OAVS individuals congenital heart defect. Chromosomal microarray analysis identified pathogenic CNVs 2/19 (10.5%) individuals, classified as uncertain significance 7/19 (36.9%) individuals....
Prolongation of cardiac repolarization (QT interval) represents a dangerous and potentially life-threatening electrical event affecting the heart. Thyroid hormones (THs) are critical for development heart function. However, little is known about THs influence on ventricular controversial effects QT prolongation reported. Human iPSC-derived cardiomyocytes (hiPSC-CMs) multielectrode array (MEA) systems were used to investigate 3,3',5-triiodo-L-Thyronine (T3) 3,3',5,5'-tetraiodo-L-Thyronine...
Pentasomy X is a rare chromosomal abnormality probably due to nondisjunction during the meiosis. Only four cases prenatally diagnosed were described until now. Our case fifth one at 20 weeks of gestational age in 39-years-old woman. She underwent invasive prenatal diagnosis for her advanced maternal without any other known risk factor. Amniocentesis performed 17 showed female 49, XXXXX karyotype. The ultrasonographic examination revealed nonspecific signs mild early fetal growth retardation...
Abstract Background Nonthyroidal Illness Syndrome (NTIS) can be detected in many critical illnesses. Recently, we demonstrated that this condition is frequently observed COVID-19 patients too and it correlated with the severity disease. However, exact mechanism through which thyroid hormones influence course of COVID-19, as well other illnesses, not clear yet treatment T4, T3 or a combination both still controversial. Aim study was to analyze body composition search possible correlation...
Mohr–Tranebjaerg syndrome (MTS) is an X-linked hereditary disorder, characterized by childhood onset of sensorineural hearing loss, dystonia, mental retardation, behavioral disturbances, visual and spasticity,1 due to mutations in the deafness–dystonia peptide-1 gene ( DDP1 ).2 Most cause protein truncation. We describe a 24-year-old man with MTS X-chromosome microdeletion involving whole as well Bruton tyrosine kinase BTK ) gene, responsible for agammaglobulinemia (XLA). In this patient,...