- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Congenital Heart Disease Studies
- Cardiovascular Disease and Adiposity
- Elasticity and Material Modeling
- Advanced MRI Techniques and Applications
- Cardiac Arrhythmias and Treatments
- Cardiovascular Health and Disease Prevention
- Hemodynamic Monitoring and Therapy
- Cardiac Structural Anomalies and Repair
- Ultrasound in Clinical Applications
- Cardiovascular and exercise physiology
- Pulmonary Hypertension Research and Treatments
- Ultrasound and Hyperthermia Applications
- Seismic Imaging and Inversion Techniques
- Climate Change and Health Impacts
- Blood Pressure and Hypertension Studies
- Artificial Intelligence in Healthcare
- Geophysical and Geoelectrical Methods
- Cardiac pacing and defibrillation studies
- Reservoir Engineering and Simulation Methods
- Cardiovascular Issues in Pregnancy
- Medical Image Segmentation Techniques
- NMR spectroscopy and applications
University of Washington
2024
Institute for Health Metrics and Evaluation
2024
Abu Dhabi National Oil (United Arab Emirates)
2018-2020
Indus Hospital
2020
West Virginia University Hospitals
2018-2019
West Virginia University
2019
Daejeon St. Mary's Hospital
2019
Mount Sinai Hospital
2018
Oregon Health & Science University
2007-2017
Zhengzhou University
2015
Detailed, comprehensive, and timely reporting on population health by underlying causes of disability premature death is crucial to understanding responding complex patterns disease injury burden over time across age groups, sexes, locations. The availability estimates can promote evidence-based interventions that enable public researchers, policy makers, other professionals implement strategies mitigate diseases. It also facilitate more rigorous monitoring progress towards national...
Individuals exhibiting "the metabolic syndrome" have multiple coronary artery disease risk factors, including insulin resistance, hyperlipidemia, hypertension, and android obesity. We performed a randomized trial to compare the effects of aerobic resistance training regimens on factors. Twenty-six volunteers who exhibited obesity at least one other factor for were or groups. Body mass index, waist-to-hip ratio, glucose, insulin, body composition, 24-hr urinary albumin, fibrinogen, blood...
Background Despite the fact that swimming is often recommended for prevention and treatment of hypertension, no study has examined potential efficacy regular exercise lowering blood pressure in hypertensive humans. Objective To test hypothesis lowers resting pressure. Design A 10-week closely supervised training program compared with a non-exercising control group. Patients Eighteen previously sedentary men women [aged 48 ± 2 years (mean SEM)] stage 1 or essential hypertension. Results The...
Introduction: Periodontal disease is a prevalent complication of type 2 diabetes mellitus (T2DM), and poor glycemic control known risk factor. This longitudinal study aimed to investigate the predictive value glycated hemoglobin (HbA1c) for periodontal progression in cohort T2DM patients Surabaya, Indonesia. Methods: A prospective was conducted at private hospital, Indonesia, from January 2021 2023. 180 with pre-existing chronic periodontitis were enrolled. parameters, including probing...
Myocardial infarction (MI) continues to be a predominant cause of mortality globally and is characterized by restricted therapeutic alternatives considerable adverse effects linked traditional treatments. This study assessed the cardioprotective properties Justicia adhatoda leaf extract against isoproterenol-induced myocardial in rats at GC, University Faisalabad. A total 32 albino Wistar were randomly allocated into four groups, with one group designated as control remaining groups...
Left ventricular (LV) twist is manifested in oppositely directed apical and basal rotation. We studied a new 3-dimensional (3D) echocardiography program (wall motion tracking; Toshiba America Medical Systems, Inc, Tustin, CA) for left rotation.We used rotation model with variable-speed motor to rotate hearts water bath. 10 freshly harvested pig hearts, which were mounted on the rotary actuator of our phantom heart base rotating apex held fixed avoid translational motion, at rotations 0...
Normal left ventricular contraction involves a twisting component that helps augment stroke volume, the unwinding of which also very usefully contributes to early diastolic filling. Abnormalities cardiac twist have been related abnormal function. We sought quantify action using new sonographically based angle-independent motion-detecting echo method.A model was developed with variable-speed motor rotate wheel in water bath. A freshly harvested pig heart mounted on it as phantom. Short axis...
Objectives We sought to determine the feasibility and reproducibility of real-time 3-dimensional echocardiography (RT3DE) for evaluation cardiac volume, mass, function characterize maturational changes these measurements in human fetuses. Methods Eighty pregnant women 2nd 3rd trimesters (59 with normal fetuses 21 congenital heart disease [CHD]) were enrolled. acquired RT3DE images using a matrix-array transducer. stroke volume (SV), combined output (CCO), ejection fraction (EF) obtained....
Aortic stenosis (AS) and aortic regurgitation (AR) are associated with congenital isolated bicuspid valve (BAV) disease. The chronic pressure overload of AS the volume AR known to impair left ventricular function. This study assessed whether two-dimensional speckle tracking echocardiography (2D-STE) is capable detecting myocardial dysfunction BAV caused by various lesions in patients retaining normal ejection fraction (EF).Thirty-two 20 healthy tricuspid (TAV) volunteers were recruited....
Objective Quantitative left ventricular mass ( LVM ) as well regional strain values may be obtained from full‐volume real time 3D echocardiography data via semi‐automated feature tracking and represent indices of heart function, both in health disease. Methods Fresh adult porcine ovine hearts were passively pumped to simulate normal cardiac motion at stroke volumes SV s) varying 30 70 mL. A 3V‐D Matrix probe, interfaced with a GE Vivid E9 ultrasound system, was used image each baseline...
Noninvasive quantification of left ventricular (LV) stroke volumes has an important clinical role in assessing circulation and monitoring therapeutic interventions for cardiac disease. This study validated the accuracy a real-time 3-dimensional (3D) color flow Doppler method performed during transthoracic echocardiography (TTE) quantifying volume flows through mitral aortic valves using dedicated offline 3D computation program compared to LV sonomicrometry open-chest animal model.Forty-six...
This study examined the physiological effect of reduced plasma cortisol (C) during prolonged exercise in humans. The effects normal C (NC) were compared with metyrapone-induced low (LC) on substrate availability and respiratory exchange ratio 2 h at ∼60% peak O consumption nine subjects. responses preexercise (Pre) levels a rest day (Con). At rest, was attenuated by ∼70% for LC NC. glucose, lactate, glycerol, β-hydroxybutyrate, alanine, branched-chain amino acids, insulin, glucagon, growth...
Background Three‐dimensional echocardiography (3 DE ) is a promising method for strain determination; however, there are temporal resolution concerns. This study aims to evaluate the feasibility and accuracy of 3 on longitudinal circumferential ( LS , CS determination infarction detection under variable frame rates FR “heart rates” (stroke [ SR ]) conditions. Methods Latex balloons were sewn into left ventricle LV 20 freshly harvested pig hearts which then passively driven by pulsatile pump...
The aim of this study is to assess the accuracy and feasibility left ventricular systolic function determined by four-dimensional echocardiography (4DE).Latex balloons were sewn into ventricle (LV) 20 freshly harvested pig hearts which then passively driven a pulsatile pump apparatus. Global longitudinal strain (GLS), global circumferential (GCS), area (GAS) ejection fraction (LVEF) derived from 4DEand two-dimensional (2DE)-derived LVEF quantified at different stroke volumes (SV) 30-70 ml...
Aims This study aimed to assess the feasibility and accuracy of nongated four‐dimensional echocardiography (4 DE ) for determining left ventricular ( LV stroke volume SV mass in a fetal heart‐sized model. Methods A balloon was inserted into 20 fresh rabbit hearts attached calibrated pulsatile pump. Ten retaining right ventricle were imaged Group A. without ventricles (RVs) B. Nongated 4D volumes obtained using Philips iU‐22 system with an X6‐1 matrix probe at SVs ranging from 1 5 mL...
Purpose: Quantitative analysis of cardiac motion is important for evaluation heart function. Three dimensional (3D) echocardiography among the most frequently used imaging modalities estimation because it convenient, real-time, low-cost, and nonionizing. However, from 3D echocardiographic sequences still a challenging problem due to low image quality corruption by noise artifacts. Methods: The authors have developed temporally diffeomorphic approach in which velocity field instead...
The aim of this study was to assess the accuracy, feasibility, and reproducibility determining stroke volume from a novel 3-dimensional (3D) color Doppler flow quantification method for mitral valve (MV) inflow left ventricular outflow tract (LVOT) at different volumes when compared with actual rate in pumped porcine cardiac model.Thirteen freshly harvested pig hearts were studied water tank. We inserted latex balloon into each ventricle MV annulus LVOT, which passively (30-80 mL) using...
Left ventricular stroke volume, mass, and myocardial strain are valuable indicators of fetal heart function. This study investigated the feasibility nongated real time three-dimensional echocardiography (RT3DE) to determine volume (SV), left mass (LVM), under different conditions.To evaluate hearts, fetal-sized rabbit hearts were used in this study. The vitro portion was carried out using a balloon inserted into LV eight fresh driven by calibrated pulsatile pump. RT3DE volumes obtained at...