A5075714752- Monoclonal and Polyclonal Antibodies Research
- Prostate Cancer Treatment and Research
- Glycosylation and Glycoproteins Research
- Medical Imaging and Pathology Studies
- Prostate Cancer Diagnosis and Treatment
- Immunodeficiency and Autoimmune Disorders
- EEG and Brain-Computer Interfaces
- Cerebrovascular and Carotid Artery Diseases
- Advanced Radiotherapy Techniques
- Cell Adhesion Molecules Research
- Heart Rate Variability and Autonomic Control
- Non-Invasive Vital Sign Monitoring
- Neuroendocrine Tumor Research Advances
- Radiomics and Machine Learning in Medical Imaging
- Cancer Diagnosis and Treatment
- Cardiovascular Disease and Adiposity
- Greenhouse Technology and Climate Control
- Food Allergy and Anaphylaxis Research
- Cytomegalovirus and herpesvirus research
- Macrophage Migration Inhibitory Factor
- Circular RNAs in diseases
- Energy, Environment, Agriculture Analysis
- Multiple and Secondary Primary Cancers
- Retinoids in leukemia and cellular processes
- interferon and immune responses
Kobe City Nishi-Kobe Medical Center
2023-2024
Osaka Ekisaikai Hospital
2023
Self-Defense Forces Central Hospital
2014-2017
Tokyo University of Science
2016
The University of Tokyo
2013-2016
University of Hyogo
2008-2009
Niigata University
1997-2007
Tokyo Medical University Hachioji Medical Center
2005
Nippon Medical School
2005
Kyoto University
2005
We investigated the location, size, and shape of cervical lymph nodes in head neck cancer, using a 7.5-MHz ultrasound scanner. First, different criteria for normal size were obtained each region; greater than 9 mm thickness internal jugular chain or 7 submandibular submental chains should be suspected harboring metastatic foci. Second, showed more rounded configuration nonmetastatic ones. Third, comparative study between vivo vitro ultrasonograms corresponding histopathological findings...
The immunoglobulin receptor Fc gamma RIIIa (CD16) is distributed on natural killer (NK) cells, macrophages, and delta T polymorphic. RIIIa-158V has a higher affinity for both monomeric immune complexed IgG1, IgG3, IgG4 than IIIa-158F. We determined RIIIa-158V/F genotypes of Japanese patients with adult periodontitis. A significant over-representation RIIIa-158F was found in recurrence, compared without making RIIIA candidate gene recurrence risk
Many elderly people show minimum periodontal tissue destruction, which might be partly due to genetic advantages in host immune response against periodontopathic bacteria. The human IgG Fc receptor IIIb on neutrophils bears a NA1-NA2 polymorphism. FcγRIIIb-NA1 displays more efficient interaction with IgGl- and IgG3-opsonized bacteria, compared the FcγRIIIb-NA2. We investigated 70-year-old Japanese population (n = 599) determine whether FcγRIIIb polymorphism was associated resistance...
Abstract: Immunoglobulin A Fc receptor (FcαRI) has been implicated in the pathogenesis of periodontitis, because increased IgA responses and FcαRI‐bearing neutrophils are observed disease lesions. Inter‐individual differences susceptibility to periodontitis may be attributable genetic variability FcαRI‐mediated immunity. We here identified an FcαRI novel polymorphism (nt 324 A‐to‐G transition) membrane‐distal extracellular domain encompassing ligand‐binding site, not resulting amino acid...
This paper proposes a functional assessment system of autonomic nervous using an air pressure sensor. The sensor can unconstraintly detect vital information by placing it under the mattress in bed. We perform heart rate variability obtained system. In this system, we employ fuzzy membership functions with dynamic parameter to RR intervals. experimental results show that intervals correlation coefficient 0.851 comparison electrocardiograph. Then errors HF (index parasympathetic system) and...
Variation screening for the immunoglobulin G Fc receptor IIB (Fc(gamma)RIIB) gene was performed with genomic DNA from 100 healthy Japanese subjects. We identified 3 non-synonymous and 2 synonymous substitutions single-nucleotide polymorphisms in an intron region. These were found to be located ligand-binding domain intron, which might alter function of Fc(gamma)RIIb.
Summary The functional bi‐allelic polymorphism of immunoglobulin G (IgG) Fc receptor (FcγR) IIa influences the efficiency human IgG2 binding. Our previous study showed that high affinity FcγRIIa genotype (‐H/H131) was associated with periodontitis risk. As interleukin‐1 (IL‐1) is one major causes periodontal tissue destruction, it hypothesized FcγRIIa‐H/H131cross‐linking could induce an increased IL‐1 release by mononuclear cells. In this study, we evaluated intracellular expressions IL‐1β...
This paper proposes functional assessment system of autonomic nervous by the heart rate variability using an air cushion sensor. The sensor can unconstraintly detect vital information sitting down on We perform obtained system. built real time display for visualizing functions. In this system, we employ fuzzy membership functions with dynamic parameter to RR intervals. experimental results show that intervals correlation coefficient 0.846 comparison electrocardiograph. Then, errors HF (index...
To evaluate the necessity of morphological images (MI) in reading somatostatin receptor scintigraphy (SRS) patients with suspected neuroendocrine gastroenteropancreatic (GEP) tumors.A Japanese multicenter clinical trial SRS was conducted 40 GEP tumors. Three experienced radiologists interpreted three separate sessions a blinded manner (1: alone, 2: MI 3: and analyzed simultaneously), results each session were compared. In addition, diagnostic abilities SRS, alone simultaneous readings...
The present study was performed to investigate the mechanism of heat-induced vasoconstriction (HIVC) in human fingers. left fingers five male subjects were immersed water controlled at an initial temperature 35.0 degrees C. blood flows (BF) index and fourth measured continuously with laser-Doppler flowmeter probes, temperatures middle finger bath also monitored using thermistor probes. Arterial pressure heart rate every minute before during local warming. A anesthetic (0.5% bupivacaine...
Direct solar gain system to get heat directly from the windows is often adopted in houses. On other hand, if amount of and thermal mass not proportionate, this will work well. We proposed blind which reflects near-infrared range upward transmits visible light. It can distribute acquired indoor adequately. evaluated direct using by experiment simulation. confirmed that could improve environment contribute energy saving.
Intraductal tubulopapillary neoplasm (ITPN) is a rare disease accounting for approximately 3% of all intraductal pancreatic tumors, with papillary mucinous (IPMN) being one the most common differential diagnoses. Both ITPN and IPMN display slow growth. A branched duct type commonly observed in IPMN, whereas derived from has been reported limited number cases; hence, its pathogenesis remains unclear.
頚部血栓化巨大動脈瘤に対し，後頚三角を利用して動脈瘤切除を行った症例を経験したので報告する．症例は82歳女性．最大径24.1mmの左頚部動脈瘤を認めるも，無症状のため経過観察していた．6年後に一過性右上下肢麻痺が出現し，MRI拡散強調画像では左前頭葉皮質に新鮮脳梗塞を認め，左頚部動脈瘤は最大径72.2mmに拡大していた．手術では乳様突起から胸鎖乳突筋前縁に沿った皮膚切開に加え，その下端から鎖骨上を外側に延長させたL字切開を行った．動脈瘤外壁には内頚静脈や周囲組織が強く癒着していた．内シャント設置後，動脈を切開した．動脈瘤内は器質化した血栓が充満しており，潰瘍形成している部分もあった．周囲組織との剝離後，動脈瘤を切断し，正常な血管壁同士を縫合して手術終了した．頚部動脈瘤に対する手術では，適切な術式選択もさることながら，適切な術野展開も重要である．