A5033719974- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Pancreatic function and diabetes
- Piperaceae Chemical and Biological Studies
- Diet, Metabolism, and Disease
- Ocean Waves and Remote Sensing
- Fluid Dynamics Simulations and Interactions
- Autophagy in Disease and Therapy
- Ginger and Zingiberaceae research
- Liver Disease Diagnosis and Treatment
- Curcumin's Biomedical Applications
- Cancer, Hypoxia, and Metabolism
- Ginseng Biological Effects and Applications
- Metabolomics and Mass Spectrometry Studies
- RNA modifications and cancer
- Ship Hydrodynamics and Maneuverability
- Adipose Tissue and Metabolism
- Metabolism, Diabetes, and Cancer
- Traditional Chinese Medicine Analysis
China University of Geosciences
2023
Guangzhou University of Chinese Medicine
2016-2019
Guangdong Provincial Hospital of Traditional Chinese Medicine
2018
This study was designed to investigate the precancerous lesions of gastric carcinoma (PLGC)‐reversing mechanisms astragaloside IV (ASIV) in N‐methyl‐N′‐nitro‐N‐nitrosoguanidine (MNNG)‐induced PLGC rats. All rats were sacrificed after 10‐week treatment. Gastric tissue analyzed by using histopathology and electron microscope. To be fully evidenced, LDHA, p53, TIGAR, MCT1, MCT4, HIF‐1α, CD147, miRNA‐34a detected Western blotting Real‐time Quantitative polymerase chain reaction (RT‐qPCR). As...
Abstract Curcumin (CUR) is known to exert numerous health‐promoting effects in pharmacological studies, but its low bioavailability hinders the development of curcumin as a feasible therapeutic agent. Piperine (PIP) has been reported enhance curcumin, underlying mechanism remains poorly understood. In an attempt find by which piperine enhances dosage ratio (CUR: PIP) and pre‐treatment with were hypothesized key factors for improving this combination. Therefore, combining at various dose...
Type 2 diabetic mellitus (T2DM), which is characterized by insulin resistance (IR), hyperglycemia and hyperlipidemia, a comprehensive dysfunction of metabolism. The receptor (INSR)/phosphoinositide 3‑kinase (PI3K)/AKT signaling pathway well acknowledged as predominant associated with glucose uptake; however, the effect streptozotocin (STZ) plus high fat sugar diet (HFSD) on proteins this requires further elucidation. In order to explore effect, T2DM rat model was constructed investigate...
Gastric cancer is recognized as one of the most common cancer. In-depth research gastric precancerous lesions (GPL) plays an important role in preventing occurrence Meanwhile, traditional treatment provides a novel sight prevention and development The current study was designed to assess effects therapy with Weipixiao (WPX) decoction on N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced GPL rats underlying molecular mechanisms. After 10-weeks treatment, all were sacrificed....
In recent decades, freak waves, characterized by their unusual high amplitude, sharp crest, and concentrated energy, have attracted researchers’ attention due to potential threat marine structures. Green-water loads caused waves can be significant may lead local damage the ship Therefore, this paper focuses on study of green-water examines structural responses bow structures under influence waves. Firstly, a three-dimensional numerical wave tank is established in which superposition model...