A5101769013- Cancer, Lipids, and Metabolism
- Cardiovascular Disease and Adiposity
- Cancer, Hypoxia, and Metabolism
- Neurological Disease Mechanisms and Treatments
- Magnetic and Electromagnetic Effects
- Cancer-related molecular mechanisms research
- Electromagnetic Fields and Biological Effects
- Traditional Chinese Medicine Analysis
- Heart Rate Variability and Autonomic Control
- MicroRNA in disease regulation
- Vagus Nerve Stimulation Research
- Immune cells in cancer
- Helicobacter pylori-related gastroenterology studies
- Autophagy in Disease and Therapy
- Smart Grid and Power Systems
- Pain Management and Treatment
- Heme Oxygenase-1 and Carbon Monoxide
- Power System Reliability and Maintenance
- Cell death mechanisms and regulation
- Power Systems Fault Detection
- Catalytic Processes in Materials Science
- RNA modifications and cancer
- Drug-Induced Ocular Toxicity
- Security and Verification in Computing
- Fault Detection and Control Systems
Hefei Institutes of Physical Science
2023-2024
High Magnetic Field Laboratory
2023-2024
Chinese Academy of Sciences
2023-2024
University of Science and Technology of China
2023-2024
Zhejiang University
2024
Shanghai University of Medicine and Health Sciences
2022-2024
China Southern Power Grid (China)
2022-2024
Taiyuan University of Technology
2024
Guangzhou University of Chinese Medicine
2018-2023
Shandong University
2022-2023
This study was designed to investigate the precancerous lesions of gastric carcinoma (PLGC)‐reversing mechanisms astragaloside IV (ASIV) in N‐methyl‐N′‐nitro‐N‐nitrosoguanidine (MNNG)‐induced PLGC rats. All rats were sacrificed after 10‐week treatment. Gastric tissue analyzed by using histopathology and electron microscope. To be fully evidenced, LDHA, p53, TIGAR, MCT1, MCT4, HIF‐1α, CD147, miRNA‐34a detected Western blotting Real‐time Quantitative polymerase chain reaction (RT‐qPCR). As...
Angiogenesis is a pathobiological hallmark of gastric cancer. However, rare studies focus on angiogenesis in precancerous lesions (GPL). Weipixiao (WPX), Chinese herbal preparation, proved clinically effective treating GPL. Here, we evaluated WPX's anti-angiogenic potential for GPL, and also investigated the possibility its mechanisms.HPLC analysis was applied to screen major chemical components WPX. After modeling N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced GPL male Sprague-Dawley...
Purpose: This study was conducted to explore the mechanism of Sijunzi Decoction (SJZ) in treatment ulcerative colitis (UC). Methods: The aimed investigate active components and targets SJZ UC by screening databases such as TCMSP, GeneCards, OMIM, Distinct, TTD, Drugbank. An online Venn tool, Cytoscape 3.7.2, Autodock Tools were used analyze targets. also a mouse model further effects SJZ. HE staining, immunofluorescence, ELISA, qPCR, Western blot detect various indices. Results: Eighty-three...
Iron-sulfur (Fe-S) clusters are essential cofactors of proteins involved in various biological systems, such as electron transport, biosynthetic reactions, DNA repair and gene expression regulation so on. cluster assembly protein IscA1 or MagR was found mitochondria most eukaryotes. is a highly conserved A-type iron iron-sulfur binding protein, with two types clusters, [2Fe-2S] [3Fe-4S], each conferring distinct magnetic properties. It forms rod-like polymer structure complex photoreceptive...
Gastric cancer is recognized as one of the most common cancer. In-depth research gastric precancerous lesions (GPL) plays an important role in preventing occurrence Meanwhile, traditional treatment provides a novel sight prevention and development The current study was designed to assess effects therapy with Weipixiao (WPX) decoction on N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced GPL rats underlying molecular mechanisms. After 10-weeks treatment, all were sacrificed....
The ability to navigate long distances is essential for many animals locate shelter, food, and breeding grounds. Magnetic sense has evolved in various migratory homing species orient them based on the geomagnetic field. A highly conserved iron-sulfur cluster assembly protein IscA proposed as an animal magnetoreceptor (MagR). Iron-sulfur binding also suggested play role MagR magnetism thus critical magnetoreception. In current study, we provide evidence distinct iron pigeons, avian that...
Jianpiyifei II granules (JPYF II), a herbal formula, are used for the treatment of chronic obstructive pulmonary disease (COPD) in Guangdong Provincial Hospital Chinese Medicine. The protective effects JPYF against bronchial epithelial cell apoptosis mice exposed to cigarette smoke (CS) and human lines (BEAS-2B 16-HBE) stimulated with extract (CSE) were investigated. Mice CS generated from 4 cigarettes/day 30 days administered dose (0.75, 1.5 3 g/kg/d) third week exposure. In CS,...
Accurately evaluating the fault type and location is important for ensuring reliability of power distribution network. A mushrooming number distributed generations (DGs) connected to system brings challenges traditional classification methods. Novel AI-based methods are mostly based on wide area measurement with assistance intelligent devices, whose economic cost somewhat high. This paper develops a super-resolution (SR) graph neural network (GNN) method in It can accurately evaluate only by...
Amauroderma rugosum (Blume & T. Nees) Torrend (Ganodermataceae) is an edible mushroom with a wide range of medicinal values. Our previous publication demonstrated the therapeutic effects water extract A. (WEA) against gastric ulcers. However, protective ethanol (EEA) on mucosa and its major active constituents have not yet been elucidated.
Birds exhibit extraordinary mobility and remarkable navigational skills, obtaining guidance cues from the Earth's magnetic field for orientation long-distance movement. Bird species also show tremendous diversity in navigation strategies, with considerable differences even within same taxa among individuals population. The highly conserved iron iron-sulfur cluster binding magnetoreceptor (MagR) protein is suggested to enable animals, including birds, detect geomagnetic navigate accordingly....
Static magnetic field (SMF) plays important roles in various biological processes of many organisms including plants, though the molecular mechanism remains largely unclear. Here this study, we evaluated different setups to test their effects on growth and development Arabidopsis ( thaliana ), discovered that plant was significantly enhanced by inhomogeneous SMF generated a regular triangular prism magnet perpendicular direction gravity. Comparative transcriptomic analysis revealed auxin...
Effective drugs for treating dementia are still rare. Danggui-Shaoyao San (DSS), a traditional Chinese medicine, has been widely used in oriental countries the treatment of various gynecological diseases. Many studies reported that DSS could ameliorate cognitive impairment. In this study, we aimed to investigate underlying mechanism on vascular impairment (VCI) rats. Chronic cerebral hypoperfusion (CCH) is one main causes VCI. CCH resulted chain pathological process, including...
Chronic obstructive pulmonary disease (COPD) is a worldwide chronic inflammatory lung disease, and influenza A virus (IAV) infection common cause of acute exacerbations COPD (AECOPD). Therefore, targeting viral infections represents promising strategy to prevent the occurrence development flare ups in AECOPD. Jianpiyifei II (JPYFII) traditional herbal medicine used China treat patients with COPD, its clinical indications are not well understood. However, investigation anti-inflammatory...
This comprehensive paper delves into the multifaceted world of contemporary architectural and environmental design, exploring an array methodologies that emphasize sustainability, technological innovation, socio-cultural integration. It begins by discussing Integrated Design Process (IDP), which fosters early-stage collaboration across various disciplines, illustrated example Seattles Bullitt Center. The then explores principles Biophilic Design, highlighting its positive impacts on human...
To investigate the mechanism underlying action of Weipixiao (WPX) in a rat's model with ameliorating gastric precancerous lesions (GPL).HPLC analysis was performed to identify chemical constituents WPX preparation. Sprague- Dawley rats were randomly assigned into control group, vitacoenzyme high-dose group (H-WPX), medium-dose (M-WPX) and low-dose (L-WPX). After modeling, treated administrated or intragastrically for consecutive 10 weeks. Gene protein expressions GSK3¦Â, C-myc, Cylin E...
This article proposes a network security protection scheme for power system embedded devices based on chip-level trusted computing, gives the overall architecture of equipment introduces principle trust chain transfer within terminals, and method using on-chip SRAM inside main control chip as PUF to construct root. Furthermore, we propose complete mechanism from booting loading that operating application, give corresponding program design framework logic. The computing designed in this was...
To realize the quantitative classification and comprehensive evaluation of tight oil reservoir in 4th Quantou Formation Songliao Basin, pore structure was quantitatively analyzed. In this study, experiments based on constant-speed mercury injection, nuclear magnetic resonance, micron CT are observation cast thin sections, scanning electron microscope is conducted. The result shows that a space mainly composed intergranular dissolved pore, residual intragranular dissolve pore. There few...
The effects of different geometric parameters the rough structure micro-channel wall on catalytic combustion efficiency methane and extinction limit have been researched.