A5101450423- Adipose Tissue and Metabolism
- Adipokines, Inflammation, and Metabolic Diseases
- Liver Disease Diagnosis and Treatment
- Peroxisome Proliferator-Activated Receptors
- Cancer-related molecular mechanisms research
- Molecular Biology Techniques and Applications
- RNA Research and Splicing
- Genetic Mapping and Diversity in Plants and Animals
- Lipid metabolism and biosynthesis
- Kruppel-like factors research
- Fibroblast Growth Factor Research
- Cholesterol and Lipid Metabolism
- Regulation of Appetite and Obesity
- RNA regulation and disease
- Genetic and phenotypic traits in livestock
- Nonmelanoma Skin Cancer Studies
- Pediatric health and respiratory diseases
- Hepatitis C virus research
- Cancer, Hypoxia, and Metabolism
- Muscle Physiology and Disorders
- Autophagy in Disease and Therapy
- melanin and skin pigmentation
- Sirtuins and Resveratrol in Medicine
- Cell death mechanisms and regulation
- Lipid metabolism and disorders
Huazhong Agricultural University
2013-2025
ZheJiang Academy of Agricultural Sciences
2025
Sichuan Cancer Hospital
2021-2024
University of Electronic Science and Technology of China
2021-2024
Jiangsu University
2022-2023
Union Hospital
2023
Huazhong University of Science and Technology
2023
First People's Hospital of Foshan
2023
Air Force Medical University
2022
Xijing Hospital
2022
Nonalcoholic fatty liver disease (NAFLD) occurs when excess fat is stored in the and it strongly linked with metabolic syndrome oxidative stress. Selenium (Se) an essential micronutrient animals, which has a variety of biological functions, including antioxidant anti-inflammatory. However, exact effect dietary selenium on NAFLD underlying molecular mechanism are not yet clear. Herein, we fed high-fat diet (HFD) to C57BL/6 mice construct vivo model, treated AML-12 cells palmitic acid (PA)...
This study aimed to investigate the therapeutic effects of magnolol on production performance in postpeak laying hens. We divided hens into three groups (ND, MAG300, MAG500) and conducted a 10-week feeding trial. The results indicated that daily supplementation with improved rate, reduced feed-to-egg ratio, controlled liver fat accumulation, alleviated ovarian oxidative stress apoptosis. Additionally, 16S rDNA analysis revealed increased microbial diversity cecum, augmented abundance...
Chronic obstructive pulmonary disease (COPD) is characterized by a chronic inflammatory response that worsened acute exacerbations. Lianhuaqingwen (LHQW) has anti-inflammatory and immune regulatory functions may inhibit the airway inflammation occurs during an exacerbation of COPD. In this study, 100 participants were recruited randomly assigned, 1 : 1, to LHQW conventional groups, which treated, respectively, with capsules Western medicine or only medicine. The scores CAT scale levels...
The molecular mechanism of arbuscular mycorrhizal fungi (AMF) in reducing cadmium (Cd) accumulation plants remains unclear. In this respect, the effects Rhizophagus intraradices (Ri) inoculation under Cd stress on rice growth, uptake along with other elements, and expression transport genes, including OsNRAMP1/5, were studied using wild-type (WT) osnramp5 mutant rice. results showed that Ri did not affect growth. was much lower than WT, as 27.6%, 17.5%, 39.9% noted grains, shoots, roots,...
Beef quality is critically determined by intramuscular fat (IMF) deposition. Retinoic acid (RA), the active metabolite of vitamin A, plays an essential regulatory role in IMF development. To systematically investigate RA-mediated regulation formation cattle, we established a concentration gradient RA supplementation and employed systematic screening approach to identify optimal dosage for modulating bovine adipocytes (IMAs) proliferation differentiation. Subsequently, leveraging integrated...
ABSTRACT This study aimed to utilize aged laying hens as a model investigate the effects of naringin on occurrence and progression metabolic dysfunction‐associated fatty liver disease (MAFLD), along with its underlying regulatory mechanisms. A total 288 hens, 50‐week‐old, were divided into four groups: normal diet (ND) group, three groups receiving 200 mg/kg (N1), 400 (N2), 600 (N3). The experiment lasted for 10 weeks, after which serum, liver, cecal contents collected from hens. Results...
Adiponectin, an adipocyte-derived hormone, is a versatile player involved in the regulation of energy homeostasis, cardiovascular disease, and diabetes. Within adipocytes, adiponectin retained lumen endoplasmic reticulum (ER) by binding to thiol protein ER resident 44 kDa (ERp44), which apparently regulated activation nuclear receptor peroxisome proliferator-activated (PPAR)-γ. However, precise role ERp44 secretion remains elusive. In present study, we investigated functional correlation...
Chemerin is a novel adipokine which abundant in adipose tissue to promote adipocyte differentiation and with significant relativity BMI insulin sensitivity. We report here the molecular characterization of porcine chemerin its receptors ChemR23 GPR1, as well their transcriptional regulation during lipogenesis. was mainly expressed liver, intestine, kidney tissue, consistent expression pattern but not ChemR23, predominantly present spleen temperately tissue. further investigated...
Twist‐related protein 2 (TWIST2) is identified as a basic helix‐loop‐helix (b‐HLH) transcription repressor by dimerizing with other b‐HLH proteins. The significance of TWIST2 has been emphasized in various tumors; however, few studies report its functions metabolism and metabolic diseases. Here we aimed to explore the novel role regulation mechanism hepatic steatosis. Our results showed that Twist2 knockdown caused mice obesity, insulin resistance, steatosis, which were accompanied...