A5100720810- Cancer-related molecular mechanisms research
- Genetic and phenotypic traits in livestock
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Lipid metabolism and disorders
- Adipose Tissue and Metabolism
- Effects of Environmental Stressors on Livestock
- RNA Research and Splicing
- Reproductive Physiology in Livestock
- Molecular Biology Techniques and Applications
- Muscle Physiology and Disorders
- Genetic Mapping and Diversity in Plants and Animals
- Animal Genetics and Reproduction
- Peroxisome Proliferator-Activated Receptors
- RNA modifications and cancer
- FOXO transcription factor regulation
- Cancer-related gene regulation
- T-cell and Retrovirus Studies
- Animal Nutrition and Physiology
- Angiogenesis and VEGF in Cancer
- Lipid metabolism and biosynthesis
- Plant Molecular Biology Research
- Cancer-related Molecular Pathways
- Genomic variations and chromosomal abnormalities
- Diabetes and associated disorders
Ningxia University
2018-2025
Tumor Hospital of Guangxi Medical University
2018-2025
Xinyang Normal University
2012-2024
South China Botanical Garden
2022-2024
China National Botanical Garden
2024
Sichuan University
2016-2024
West China Hospital of Sichuan University
2016-2024
Georgia Institute of Technology
2023
The Fourth People's Hospital of Ningxia Hui Autonomous Region
2021-2023
Xi'an Shiyou University
2023
Muscle development is regulated under a series of complicate processes, and non-coding RNAs, such as microRNAs (miRNAs) circular RNAs (circRNAs), have been reported to play important roles in regulating myoblast proliferation differentiation. We found that miR-107 expression was high skeletal muscle Qinchuan cattle. Overexpression inhibited bovine myoblasts differentiation protected cells from apoptosis. Wnt3a identified target by luciferase activity, real-time qPCR, western blotting assays....
Circular RNAs (circRNAs) have been identified in various tissues and cell types from human, monkey, porcine, mouse. However, knowledge on circRNAs bovine muscle development is limited. We downloaded analyzed the sequencing data of skeletal tissue, further characterized role a candidate circRNA ( circFUT10 ) development. Quantitative real‐time PCR (qPCR) Western blot assays were used to confirm expression genes involved myoblasts differentiation proliferation. Flow cytometry was performed...
Diarrhea is a prevalent disease among calves, which significantly hinders their growth and development, thereby impacting farm productivity revenue. This study aimed to investigate the impact of diarrhea on calf growth. Holstein male calves with similar birth weight (39.5 ± 4.2 kg) were included in this study, key parameters such as fecal score, incidence, performance from weaning measured. Rectal samples both diarrheic (n = 24) healthy aged 1-4 weeks analyzed using 16S rRNA gene sequencing...
Skeletal muscle development is regulated by a series of regulatory factors, and also including noncoding RNA, especially microRNAs (miRNAs). Recently, miR-148a has been found to be involved in murine C2C12 differentiation targeting ROCK1. However, the function miR-148a-3p for proliferation apoptosis bovine cells not determined. In this study, we that was highly expressed fetal skeletal exhibited decreasing trend during its growth phase. Functional studies indicated gain inhibited promoted...
Skeletal muscle is not only an important tissue involved in exercise and metabolism, but also part of livestock poultry meat products. Its growth development determines the output quality to a certain extent, has impact on economic benefits animal husbandry. complex regulatory network process, its molecular mechanism needs be further studied.We used weighted co-expression (WGCNA) single gene set enrichment analysis (GSEA) study RNA-seq data bovine differential expression analysis, core genes...
ABSTRACT In this paper, we consider a nonlinear equation involving uniformly elliptic nonlocal operator in the upper half space. We first develop narrow region principle for antisymmetric functions unbounded domains, which assume that has polynomial growth instead of usual decay condition at infinity. Then obtain monotonicity positive solutions equations space by direct method moving planes, extends monotonic result fractional equation. Based on results, prove existence bounded whole believe...
Abstract Skeletal muscle is the most abundant tissue in body. The development of skeletal cell complex and affected by many factors. A sea microRNAs (miRNAs) have been identified as critical regulators myogenesis. MiR‐208b, a muscle‐specific miRNA, was reported to connection with fiber type determination. However, whether miR‐208b has effect on proliferation under ascertained. In our study, cyclin‐dependent kinase inhibitor 1A ( CDKN1A ), which participates cycle regulation, predicted then...
In this study, it is shown for the first time that a reduced graphene oxide (rGO) carrier has 20-fold higher catalysis rate than in Ag
Severe acute pancreatitis (AP) is associated with high morbidity and mortality. Early severity stratification remains a challenging issue to overcome improve outcomes. We aim find novel plasma cytokines for the early identification of severe AP according revised Atlanta criteria. In this prospective observational study, 30 cytokines, screened semiquantitatively human multicytokine array, were submitted quantitative determination using either microparticle-based multiplex immunoassays...
Abstract MicroRNAs (miRNAs) have been established to regulate skeletal muscle development in mammals. However, few studies conducted on the regulation of proliferation and differentiation bovine myoblast cells by miRNAs. The aim our study was explore function miR‐483 cell myoblast. Here, we found that declined both stages cells. During phase, overexpression downregulated cycle–associated genes cyclin‐dependent kinase 2 ( CDK2 ), proliferating nuclear antigen PCNA ) messenger RNA (mRNA),...
Abstract Background The domestic buffalo (Bubalus bubalis) is an essential farm animal in tropical and subtropical regions, whose genomic diversity yet to be fully discovered. Results In this study, we describe the demographic events selective pressures of by analyzing 121 whole genomes (98 newly reported) from 25 swamp river breeds. Both uniparental biparental markers were investigated provide final scenario. ancestors diverged ~0.23 million years ago then experienced independent histories....
Abstract Background In China, although buffaloes are abundant, beef is mainly obtained from cattle, and this preference attributed to the low intramuscular fat (IMF) content of buffalo. Genetic factors an important driver that affects IMF deposition. Results To reveal intrinsic responsible for buffalo, mRNA expression patterns in muscle adipose tissue between buffalo cattle were characterized by RNA sequencing analysis. The Nanyang was higher than Xinyang A total 1566 mRNAs expressed showed...