A5100747977- Nanoplatforms for cancer theranostics
- Luminescence and Fluorescent Materials
- X-ray Diffraction in Crystallography
- Molecular Sensors and Ion Detection
- Crystallization and Solubility Studies
- Optical Imaging and Spectroscopy Techniques
- Photoacoustic and Ultrasonic Imaging
- Advanced Nanomaterials in Catalysis
- Radiation Effects in Electronics
- Radar Systems and Signal Processing
- Advanced Photocatalysis Techniques
- Advancements in Semiconductor Devices and Circuit Design
- Plasma Applications and Diagnostics
- Spectroscopy Techniques in Biomedical and Chemical Research
- Sulfur Compounds in Biology
- Luminescence Properties of Advanced Materials
- Advanced SAR Imaging Techniques
- Advanced biosensing and bioanalysis techniques
- Advanced Antenna and Metasurface Technologies
- Catalytic Processes in Materials Science
- Astrophysics and Cosmic Phenomena
- Electrohydrodynamics and Fluid Dynamics
- Carbon Nanotubes in Composites
- Antenna Design and Optimization
- Metamaterials and Metasurfaces Applications
East China University of Science and Technology
2017-2025
Anhui Agricultural University
2024
Xidian University
2020-2024
Suzhou Institute of Nano-tech and Nano-bionics
2023-2024
Chinese Academy of Sciences
2006-2024
Ocean University of China
2022-2024
Wuhan Polytechnic University
2024
Shanghai Power Equipment Research Institute
2020-2024
National Institute for Occupational Health and Poison Control
2024
Jiangsu Maritime Institute
2022-2024
Chemiluminescence (CL)-based technologies have revolutionized in vivo monitoring of biomolecules. However, significant technical hurdles limited the achievement trigger-controlled, bright, and enriched CL signal. Herein, a dual-lock strategy uses sequence-dependent triggers for bright optical imaging with real-time fluorescent signal ultra-sensitive These probes can obtain an analyte-triggered accumulation stable pre-chemiluminophore aggregation-induced emission (AIE), then exhibits rapid...
Abstract CLE peptides have been implicated in various developmental processes of plants and mediate their responses to environmental stimuli. However, the biological relevance most genes remains be functionally characterized. Here, we report that CLE9 , which is expressed stomata, acts as an essential regulator induction stomatal closure. Exogenous application or overexpression effectively led closure enhanced drought tolerance, whereas loss‐of‐function mutants were sensitivity stress....
An ongoing revolution in fluorescence-based technologies has transformed the way we visualize and manipulate biological events. enduring goal this field is to explore high-performance fluorogenic scaffolds that show tunability capability for vivo analysis, especially small-molecular near-infrared (NIR) fluorophores. We present a unique bent-to-planar rehybridization design strategy NIR scaffolds, thus yielding palette of switchable bent/planar Si-rhodamines span from visible NIR-II...
In this article, we introduce a simple method to characterize optical properties and blood oxygenation in tissue using spatially resolved, steady-state reflectance. The considers multiple source-detector separations larger than 2 cm, i.e. 20 times the mean free path tissue, makes an approximation linearize relationship between separation Simulation results show that errors of algorithm due are less 10%. Using calibration sample, calculate from slope intercept absorption reduced scattering...
The real-time monitoring of nitric oxide (NO) at the subcellular level is still a great challenge. To attain this goal, we developed fast and selective near-infrared (NIR) fluorescent probe for targeted tracing endogenous NO. This possesses vital features detection intracellular NO including significant turn-on NIR response, high specificity, response by controlled photoinduced electron transfer (PET) process, which applicable to in mitochondria.
Abstract Photodynamic therapy (PDT) is a promising technique for cancer therapy, providing good therapeutic efficacy with minimized side effect. However, the lack of oxygen supply in hypoxic tumor site obviously restricts generation singlet ( 1 O 2 ), thus limiting PDT. So far, strategies to improve PDT usually rely on complicated nanosystems, which require sophisticated design or complex synthetic procedure. Herein, iodine‐rich semiconducting polymer nanoparticles (SPN‐I) enhanced PDT,...
High-fidelity tracking of specific enzyme activities is critical for the early diagnosis diseases such as cancers. However, most available fluorescent probes are difficult to obtain in situ information because tending facile diffusion or inevitably suffering from aggregation-caused quenching (ACQ) effect. In this work, we developed an elaborated near-infrared (NIR) aggregation-induced emission (AIE)-active probe, which composed a hydrophobic 2-(2-hydroxyphenyl) benzothiazole (HBT) moiety...
To investigate and better understand the mechanism of coal spontaneous combustion, distributions, evolution, oxidation characteristics functional groups in different samples were characterized using situ Fourier transform infrared (FTIR) electron paramagnetic resonance (EPR) experiments. The macroscopic combustion relation to also analyzed thermogravimetric/differential scanning calorimetry–FTIR coupling technique. experimental results indicated that −OH was most active combustion. It not...
Photocaging holds promise for the precise manipulation of biological events in space and time. However, current near-infrared (NIR) photocages are oxygen-dependent their photolysis lack timely feedback regulation, which has proven to be major bottleneck targeted therapy. Herein, we present a hypoxia-dependent photo-activation mechanism dialkylamine-substituted cyanine (Cy-NH) accompanied by emissive fragments generation, was validated with retrosynthesis spectral analysis. For first time,...
A zwitterionic chemiluminescence strategy makes a breakthrough in highly selective sensing of 1 O 2 towards FDA-approved phototherapy through suppressing inherent photo-induced side reactions.
We report an innovative two-dimensional orthogonal strategy which is sequentially triggered with hydrolysis-initiated fluorescence and photocycloaddition-induced chemiluminescence, enabling identification quantitation of human serum albumin bovine albumin.
Glutathione (GSH) plays a critical role in various biological processes maintaining oxidative homeostasis. However, current reversible probe fluorescence emission is usually the visible region, making it difficult to monitor glutathione levels deep tissues and vivo. Here, we developed near-infrared probe, Flav-N, for real-time tracking of GSH cells tissues, which undergoes fast Michael addition reactions with biothiols. This Flav-N showed rapid response at time less than 5 s (k = 1286...
We developed a curcuminoid difluoroboron-based fluorescent probe for tracking endogenous GGT activity with dual-channel light-up near-infrared (NIR) imaging.