A5027105275- Neuroblastoma Research and Treatments
- Genomics and Rare Diseases
- Genetics and Neurodevelopmental Disorders
- Transcranial Magnetic Stimulation Studies
- Venous Thromboembolism Diagnosis and Management
- Ovarian cancer diagnosis and treatment
- Congenital heart defects research
- Renal cell carcinoma treatment
- Genomics and Chromatin Dynamics
- Metabolism and Genetic Disorders
- Immunodeficiency and Autoimmune Disorders
- Mitochondrial Function and Pathology
- DNA Repair Mechanisms
- RNA modifications and cancer
- RNA and protein synthesis mechanisms
- Lymphoma Diagnosis and Treatment
- Intraperitoneal and Appendiceal Malignancies
- Ultrasound and Hyperthermia Applications
- Neurological disorders and treatments
- Epilepsy research and treatment
- Uterine Myomas and Treatments
- Lung Cancer Research Studies
- Cancer, Hypoxia, and Metabolism
- Parkinson's Disease Mechanisms and Treatments
- Hematological disorders and diagnostics
Roche (China)
2024
Shandong First Medical University
2023-2024
Cancer Hospital of Huanxing Chaoyang District Beijing
2024
Capital Medical University
2018-2023
Beijing Children’s Hospital
2018-2023
Beijing Tian Tan Hospital
2023
Shandong Provincial QianFoShan Hospital
2023
Beijing Obstetrics and Gynecology Hospital
2022
First-line bevacizumab plus carboplatin and paclitaxel (CP) is approved for stage III/IV ovarian cancer treatment following initial surgical resection, based on global phase III GOG-0218 ICON7 trials. This study evaluated the efficacy safety of + CP as first-line therapy in Chinese patients.
To analyze the factors affecting delayed chemotherapy in children with Burkitt lymphoma (BL) and their influence on prognosis.
Objective: To summarize the clinical characteristics of high-risk neuroblastoma (HR-NB) in a single center, analyze prognostic factors HR-NB. Methods: The data children with HR-NB who were treated and followed up at hematology-oncology center Beijing Children's Hospital from February 1, 2007 to June 30, 2018 analyzed retrospectively. features summarized. Kaplan-Meier method was used for survival analysis Cox regression factors. last follow-up time 2019. Results: A total 458 enrolled this...
Objective: To investigate the etiology of epilepsy onset before 6 months old and improve clinical understanding. Methods: The medical history, electroencephalogram, brain imaging, genetic examination other data 340 patients who were diagnosed with under age hospitalized in Department Neurology, Beijing Children's Hospital, Capital Medical University between January 2017 December 2018 retrospectively analyzed. Rank sum test was used to compare ages different etiologic groups. Results: Of...
患儿 女，7岁，因“间断腹痛20 d”就诊于北京儿童医院。经影像学检查、肿瘤标志物、病理检查诊断为卵巢无性细胞瘤。既往因反复感染、淋巴结肿大，经免疫功能测定和基因检测诊断为PI3Kδ过度活化综合征（APDS）。予西罗莫司、丙种球蛋白治疗APDS的同时，经过手术及化疗，肿瘤完全缓解，患儿感染频率较前下降。.
To explore the efficacy and safety of Rivaroxaban in preventing catheter related thrombosis (CRT) patients with breast cancer who are undergoing central venous chemotherapy, provide basis for making standardized prevention treatment strategies.
Objective: To investigate the clinical features, laboratory characteristics and genetic diagnosis of Kabuki syndrome (KS). Methods: Between September 2014 2016, seven children with clinically diagnosed KS from neurology department, Beijing Children Hospital, Capital Medical University were included in this study. Three them male 4 female aged 19 days to 6 years months a median age 3 1 month. The imaging materials, gene tests analyzed prospectively. Results: Clinical manifestation:...
Objective: To estimate the safety of myomectomy in twin pregnant women with intramural myomas during cesarean section. Methods: The clinical data 145 cases pregnancies who were delivered by section Beijing Obstetrics and Gynecology Hospital, Capital Medical University from June 2013 to December 2021 collected. Maternal demographics, fibroids' characteristics, maternal fetal outcomes compared between groups (myomectomy group, 49 cases) only (non-myomectomy 96 cases). Results: Compared...
妊娠合并子宫肌瘤孕妇的剖宫产率高达50%。为避免严重产后出血、弥漫性血管内凝血和子宫切除术等，传统上并不主张在剖宫产术时行子宫肌瘤剔除术。但近些年不断有研究表明，剖宫产术同时行子宫肌瘤剔除术并不增加产后出血和其他术后并发症的风险，对于有指征的子宫肌瘤孕妇，由经验丰富的医师行剖宫产+子宫肌瘤剔除术是安全可行的。目前，对于不同特征的子宫肌瘤，剖宫产术时是否剔除尚无统一标准。.
Objective: To analyse the clinical and gene characteristics of GRIN2B related neurological developmental disorders in children. Methods: The data 11 children with from November 2016 to February 2021 were collected Department Neurology, Beijing Children's Hospital, Capital Medical University, National Center for Health analyzed retrospectively. features, electroencephalogram (EEG), brain imaging testing results summarized. Results: Among 6 boys 5 girls. Two them diagnosed epileptic...
Objective: To analyze the clinical and molecular diagnostic status of Fanconi anemia (FA) in China. Methods: The General situation, manifestations chromosome breakage test genetic results 107 pediatric FA cases registered Chinese Blood Marrow Transplantation Registry Group (CBMTRG) Children (CCBMTRG) from August 2009 to January 2022 were analyzed retrospectively. with FANCA gene variants divided into mild severe groups based on type variant, Wilcoxon-test was used compare phenotypic...
Objective: To investigate the effects of electrode activated contact location, volume tissue (VTA) and age on non-motor symptoms, such as emotional symptoms cognitive function, in Parkinson's disease (PD) patients with deep brain stimulation (DBS). Methods: PD who underwent DBS subthalamic nucleus (STN) at Department Functional Neurosurgery Beijing Tiantan Hospital from September 1, 2020 to August 31, 2022 were retrospectively enrolled. The International Parkinson Movement Disorder...
Objective: To summarize the detailed clinical characteristics and genetic features of benign infantile epilepsy with PRRT2 mutation, in order to improve understanding disease. Methods: The data results 40 patients mutation who were diagnosed treated neurology department National Center for Children's Health (Beijing) , Beijing Hospital affiliated Capital Medical University from January 2002 October 2017 their affected family members analyzed. Results: Forty recruited this study, 18 males 22...
同卵三胞胎，女，6月龄，其中三胞胎之一、之二完善腹部超声、肝脏穿刺活检、神经元特异性烯醇化酶及肝脏穿刺病理等检查，诊断为神经母细胞瘤（国际神经母细胞瘤4S期，低危组），原发灶位于三胞胎之一左侧肾上腺。三胞胎之一经手术及化疗，三胞胎之二经化疗，随访肝功能正常，腹部超声示肝脏不大，腹部未见新发病灶。三胞胎之三经肝脏穿刺病理提示非嗜肝病毒性肝损伤改变。三胞胎中2例同时患有神经母细胞瘤罕见。.