- Esophageal and GI Pathology
- Dysphagia Assessment and Management
- Tracheal and airway disorders
- Cerebral Venous Sinus Thrombosis
- Intracranial Aneurysms: Treatment and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Migraine and Headache Studies
- Neurosurgical Procedures and Complications
- Anesthesia and Neurotoxicity Research
- Thermal Regulation in Medicine
- Peripheral Nerve Disorders
- Viral Infections and Vectors
- Nerve Injury and Rehabilitation
- Genetic Neurodegenerative Diseases
- Yersinia bacterium, plague, ectoparasites research
- Cerebrovascular and genetic disorders
- Orthopedic Surgery and Rehabilitation
- Sympathectomy and Hyperhidrosis Treatments
- Neuroscience and Neuropharmacology Research
- Intracerebral and Subarachnoid Hemorrhage Research
- Cannabis and Cannabinoid Research
- Vector-borne infectious diseases
Klinikum Darmstadt
2018-2024
Hospital Universitario Fundación Jiménez Díaz
2013-2014
Biomedical Research Networking Center on Neurodegenerative Diseases
2008
Abstract Cannabinoid agonists might serve as neuroprotective agents in neurodegenerative disorders. Here, we examined this hypothesis a rat model of Huntington's disease (HD) generated by intrastriatal injection the mitochondrial complex II inhibitor malonate. Our results showed that only compounds able to activate CB 2 receptors were capable protecting striatal projection neurons from malonate‐induced death. That receptor are was confirmed using selective antagonist, SR144528, and...
Abstract Introduction Neurogenic dysphagia defines swallowing disorders caused by diseases of the central and peripheral nervous system, neuromuscular transmission, or muscles. is one most common at same time dangerous symptoms many neurological diseases. Its important sequelae include aspiration pneumonia, malnutrition dehydration, affected patients more often require long-term care are exposed to an increased mortality. Based on a systematic pubmed research related original papers, review...
Targeted temperature management (TTM) might improve outcome of patients with severe subarachnoid hemorrhage (SAH) in which vasospasm, delayed cerebral ischemia (DCI), and increased intracranial pressure (ICP) are frequent complications. A series (n = 3) aneurysmatic SAH were treated by TTM if they developed ICP crisis and/or vasospasm diagnosed angiography. Once these complications detected, body core (BCT) was rapidly decreased to 35°C or 33°C, necessary. BCT induced maintained surface...
Background: The clinical course of patients with aneurysmal SAH (aSAH) is often dynamic and highly unpredictable. Since its management varies between hospitals despite guidelines, this survey aimed to assess the current state intensive care treatment for aSAH in German-speaking region provide insights that could aid standardization setting. Methods: From February 2023 April 2023, medical professionals German Interdisciplinary Association Intensive Care Emergency Medicine (DIVI), Initiative...
Dysphagie ist insbesondere bei den neurologisch erkrankten Intensivpatienten ein Problem, wird aber auch Patienten ohne neurologische Vorerkrankungen nach längerer Intubationsdauer beobachtet 1, 2, 3. Die FEES hat sich hier als regelhaft eingesetzte Diagnostik etabliert 4. Untersuchung kann direkt am Krankenbett durchgeführt werden und das Sekretmanagement die pharyngeale laryngeale Sensibilität können präzise beurteilt werden.