A5022155729- Lung Cancer Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Treatments and Mutations
- Pleural and Pulmonary Diseases
- Ferroptosis and cancer prognosis
- Radiomics and Machine Learning in Medical Imaging
- Gastric Cancer Management and Outcomes
- Pharmaceutical Practices and Patient Outcomes
- Lipoproteins and Cardiovascular Health
- Wind and Air Flow Studies
- Fluid Dynamics and Vibration Analysis
- Vibration and Dynamic Analysis
Fudan University Shanghai Cancer Center
2023-2025
Shanghai Medical College of Fudan University
2023-2024
Dalian University of Technology
2024
Fudan University
2019-2023
We aimed to prospectively evaluate our previously proposed selective mediastinal lymph node (LN) dissection strategy for peripheral clinical T1N0 invasive NSCLC.This is a multicenter, prospective trial in China. set six criteria predicting negative LN stations and finally guiding dissection. Consolidation tumor ratio less than or equal 0.5, segment location, lepidic-predominant adenocarcinoma (LPA), hilar nodes (stations 10-12), visceral pleural invasion (VPI) were used separately...
The flow-induced vibrations (FIVs) of two identical tandem square cylinders with mass ratio m * = 3.5 at Reynolds number Re 150 are investigated through two-dimensional direct numerical simulation (DNS) and linear stability analysis over a parameter range spacing 1.5 ≤ L 5 reduced velocity 3 U r 34. Three kinds FIV responses, namely vortex-induced vibration (VIV), biased oscillation (BO) galloping (GA), identified. FIVs then further classified into the branches initial VIV (IV), resonant (RV...
Aims There are limited data on programmed death ligand 1 (PD-L1) expression in oesophageal cancer (OC) from multicentre studies conducted across China. We aimed to determine the prevalence of high PD-L1 patients with advanced OC. Methods The EXCEED study was a multicentre, retrospective analysis six tertiary hospitals that evaluated adults OC or head and neck squamous cell carcinoma. at each site according standardised protocol. primary outcome (Combined Positive Score (CPS) ≥10) surgical...
Background: This study aims to assess the diagnostic accuracy of intraoperative frozen section (FS) in determining pathological subtypes among patients diagnosed with cT1N0M0 invasive lung adenocarcinoma. Materials and methods: was a prospective, multicenter (seven centers China) clinical trial Eastern Cooperative Thoracic Oncology Projects (ECTOP-1015). Patients adenocarcinoma were enrolled study. Pathological images obtained from FS final pathology (FP) reviewed by at least two...
Objective: To investigate the value of intraoperative assessment spread through air spaces (STAS) on frozen sections (FS) in peripheral small-sized lung adenocarcinoma. Background: Surgical decision-making based FS diagnosis STAS may be useful to prevent local control failure after sublobar resection. Methods: We conducted a multicenter prospective observational study consecutive patients with cT1N0M0 invasive adenocarcinoma evaluate accuracy for detection STAS. The final pathology (FP) was...
Abstract Introduction: Programmed cell death ligand-1 (PD-L1) is the ligand of programmed death-1 (PD-1), a member immunoglobulin gene superfamily that plays role in death. Accumulating evidence anti-PD-1 therapy has showed improved survival benefit for esophageal cancer (EC) patients. PD-L1 emerged as crucial predictor efficacy immunotherapy. However, understanding biomarker complicated by various immunohistochemistry platforms, antibodies, scoring systems, and cut-offs Although expression...
Abstract Background Statin remains a mainstay in the prevention and treatment of cardiovascular diseases. utilization has evolved over time many countries, but data on this topic from China are quite limited. This study aimed to investigate changing trends statins prescription, as well detail statin through successive longitudinal study. Methods Prescription database was established based electronic health records retrieved hospital information system Jinshan Hospital, Fudan University...