- Cervical Cancer and HPV Research
- Antifungal resistance and susceptibility
- Reproductive tract infections research
- Fungal Infections and Studies
- Parasitic Infections and Diagnostics
- Herpesvirus Infections and Treatments
- Atmospheric and Environmental Gas Dynamics
- Autophagy in Disease and Therapy
- MicroRNA in disease regulation
- Fermentation and Sensory Analysis
- Geometry and complex manifolds
- Plant Disease Resistance and Genetics
- Genomics and Phylogenetic Studies
- Pelvic floor disorders treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Biochemical and biochemical processes
- Stoma care and complications
- Iron Metabolism and Disorders
- Marine Sponges and Natural Products
- Opinion Dynamics and Social Influence
- Analytic and geometric function theory
- Antiplatelet Therapy and Cardiovascular Diseases
- Infectious Diseases and Mycology
- Anesthesia and Neurotoxicity Research
- Bioactive Natural Diterpenoids Research
Xinxiang Medical University
2024-2025
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
2023-2025
University of Electronic Science and Technology of China
2025
Shanghai East Hospital
2022-2024
Aerospace Information Research Institute
2024
Chinese Academy of Sciences
2024
Shanghai Cancer Institute
2024
Renji Hospital
2024
Shanghai Jiao Tong University
2024
Affiliated Hospital of Nantong University
2024
Abstract INTRODUCTION Blood phosphorylated tau at threonine 217 (tau‐PT217) is a newly established biomarker for Alzheimer's disease and postoperative delirium in patients. However, the mechanisms consequences of acute changes blood tau‐PT217 remain largely unknown. METHODS We investigated effects anesthesia/surgery on aged mice, evaluated associated B cell populations, neuronal excitability anterior cingulate cortex, delirium‐like behavior using positron emission tomography imaging,...
The cardiac magnetic resonance (CMR) T2* mapping technique is widely used to quantify myocardial iron and assess overload in patients with transfusion-dependent thalassemia (TDT). However, the value of T2 detecting its consistency myocardium pediatric are unknown. Thus, this study sought explore utility feasibility using overload, provide an alternative non-invasive method for assessment clinical practice. Vitro iron-water phantom models different concentrations were analyze correlation...
Abstract Purpose The objective of this multicenter study was to compare the diagnostic performance lateral flow assay (LFA) and enzyme-linked immunosorbent (ELISA) detect Dynamiker Aspergillus Galactomannan levels in serum bronchoalveolar lavage fluid (BALF) samples for I. Methods We registered 310 clinically suspected infection patients from December 2021 February 2023 classified them into subgroups as “IA group” “non-IA based on latest EORTC/MSG guidelines. immunoassays were analyzed by...
Pulmonary invasive fungal infection in immunocompromised hosts is difficult to diagnose, and current tools for diagnosis or monitoring of response antifungal treatments have inherent limitations. Droplet digital PCR (ddPCR) has emerged as a promising tool pulmonary pathogen detection with high sensitivity. This study presents novel ddPCR panel rapid sensitive identification pathogens. First, method detecting three genera, including Pneumocystis, Aspergillus, Cryptococcus, was established...
The aim of this study is to understand the feelings and experiences main caregivers temporary ostomy patien ts with Crohn's disease (CD). And explore caregivers' inner feelings, provide reference basis for constructing health education content CD patients a stoma. A qualitative descriptive approach was used conduct an unstructured interview among 11 primary enterostomy from gastroenterology department Second Hospital Nanjing. Participants were selected using purposive sampling technique....
Background: Aspergillus spp. infection in immunocompromised patients results increasing morbidity and mortality. This study investigated clinical microbiological characteristics of aspergillosis a Chinese tertiary teaching hospital. Methods: A total 114 with were included over 5-year period at Ruijin Hospital. In sum, strains isolated identified species level using matrix-assisted laser desorption ionization time-of-flight mass spectrometry, confirmed by ITS gene region β-tubulin ( BenA )...
Glioma is the most frequent type of malignancy that may damage brain with high morbidity and mortality rates patients' prognoses are still dismal. Ferroptosis, a newly uncovered mode programmed cell death, be triggered to destroy glioma cells. Nevertheless, significance ferroptosis-related genes (FRGs) in predicting prognosis individuals mystery.
CO2 is one of the primary greenhouse gases impacting global climate change, making it crucial to understand spatiotemporal variations CO2. Currently, commonly used satellites serve as means observation, but they often suffer from striping issues and fail achieve complete coverage. This paper proposes a method for constructing comprehensive high-spatiotemporal-resolution XCO2 dataset based on multiple auxiliary data sources satellite observations, utilizing simple deep neural network (DNN)...
Cervical cancer induced by human papillomavirus (HPV) infection poses a serious threat to women's health. Studies have shown that Trichomonas vaginalis (T. vaginalis), which is widely prevalent globally, can facilitate HPV infection. However, the underlying mechanism remains unclear. This study found T. significantly enhanced in HaCaT cells and mouse vaginas through vivo vitro experiments, promoted expression of membrane receptor molecules CD151 HSPG2. The rate CD151/HSPG2 levels were...
<title>Abstract</title> <bold>Background:</bold> An increasing number of studies have identified <italic>Trichomonas vaginalis </italic>(<italic>T. vaginalis</italic>) as a risk factor for human papillomavirus (HPV) infection, yet experimental data and the mechanisms involved are still lacking. <bold>Methods:</bold> Wild-type <italic>T. vaginalis</italic> adhesion protein 33 (TvAP33) knockdown vaginalis</italic>were used to infect HaCaT cells vaginal tissue mice, while were also transfected...
Prenyltransferases act essential roles in the prenylation modification, which is significant for proteins, like small GTPases to execute various important activities Toxoplasma gondii (T.gondii). The structures and partial functions of prenyltransferases (FTase, GGTase-I, GGTase-II) process have been dissected T. gondii. However, cellular effects on type 2-ME49 strain are largely unknown. To address this gap, CRISPR/Cas9-based gene-editing technology was employed construct conditional...
In this paper, we propose a new influence spread model, namely, Complementary\&Competitive Independent Cascade (C$^2$IC) model. C$^2$IC model generalizes three well known i.e., boosting (IB) campaign oblivious (CO)IC and the IC-N (IC with negative opinions) This is first that considers both complementary competitive comprehensively under multi-agent environment. Correspondingly, maximization (C$^2$IM) problem. Given an ally seed set rival set, C$^2$IM problem aims to select of assistant...
Abstract Microbes are major contributors to the unique fragrance of Maotai liquor, in which Bacillus sp. is recognized as main flavor-producing strain. However, studies with respect importance, sensitivity and optimal ranges factors influencing flavor components secreted by have not been reported. In this paper, a thermophilic strain sp., isolated from black part Daqu, was chosen representative study how (inoculum size, temperature incubation time) influenced production (acetic acid, 2,...
Background: Recent studies have confirmed that microRNA-223 may participate in high-on clopidogrel treatment platelet reactivity. Clopidogrel requires hepatic enzyme metabolic activation to produce its metabolite with pharmacological activity, as a result, there are few researches about The aim of the current study is explore possible regulatory mechanism between and reactivity after treatment. Methods: In this study, we established an experimental model MEG-01 cells treated human liver...