A5086768434- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Acute Lymphoblastic Leukemia research
- Ubiquitin and proteasome pathways
- Lung Cancer Treatments and Mutations
- Cytokine Signaling Pathways and Interactions
- HER2/EGFR in Cancer Research
- Multiple Myeloma Research and Treatments
- Natural product bioactivities and synthesis
- Flavonoids in Medical Research
- Nanoparticle-Based Drug Delivery
- Curcumin's Biomedical Applications
- Pesticide Exposure and Toxicity
- Synthesis and Biological Evaluation
- Synthesis and Characterization of Heterocyclic Compounds
- Mosquito-borne diseases and control
- Synthesis and biological activity
- Nanoparticles: synthesis and applications
- Natural Language Processing Techniques
- Topic Modeling
- Phytochemicals and Antioxidant Activities
- Peptidase Inhibition and Analysis
- S100 Proteins and Annexins
- Paraquat toxicity studies and treatments
- Diverse Scientific Research Studies
University of Arkansas at Little Rock
2025
University of Arkansas for Medical Sciences
2019-2024
Victoria University
2023
Jamia Millia Islamia
2016-2021
Aligarh Muslim University
2013
Herein, we have shown the eco-friendly and low-cost synthesis of biogenic copper oxide nanoparticles (CuONPs) from Delonix regia (D. regia) leaf extract in aqueous medium. The formation CuONPs was characterized by ultraviolet (UV)-visible, Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) scanning electron microscopy (SEM) as well transmission (TEM). Characterization green synthesized demonstrated a UV–visible peak at 273 nm. Particle size analysed TEM monograph range...
Paraquat (PQ), a quaternary nitrogen herbicide, is commonly used as pesticide despite of its high toxicity. Our study evaluated the effect subchronic PQ exposure on neuropathology, genotoxicity, and antioxidant activity nervous tissue Drosophila melanogaster. We also explored behavioral D. Furthermore, we attempted to validate mechanism by evaluating PQ-induced cytotoxicity D-Mel2 cell lines. The fruit fly melanogaster serves feasible model understand neurodegenerative diseases. shows...
Abstract Expression of the serine/threonine kinase never in mitosis gene A (NIMA)–related 2 (NEK2) is essential for entry into via its role facilitating centrosome separation. Its overactivity can lead to tumorigenesis and drug resistance through activation several oncogenic pathways, including AKT. Although cancer-enabling activities NEK2 are documented many malignancies, correlations with poor survival myeloma, breast, non–small cell lung cancer, little known about lymphoma. Here, tumors...
Curcumin is a potent anticancer agent and has great potential efficacy against different types of cancers. A major disadvantage curcumin, however, its poor solubility bioavailability.The aim the present work to synthesize chitosan curcumin-loaded nanoparticles their characterization through various physicochemical methods cellular uptake in cervical cancer cell line SiHa.Chitosan were synthesized method ionic gelation with sodium Tripolyphosphate (TPP). In addition, internal structure...
Abstract The present work involves a pharmacophore hybridization strategy to combine key biologically active scaffolds. study led the synthesis of quinoline based oxadiazole‐triazole conjugates with favorable physicochemical properties as anti‐cancer agents. Among synthesized compounds 8(a–p) , in vitro screening against panel four cancer cell lines identified compound 8k, o ‐chloro substitution on phenyl ring, potent human lung carcinoma (A‐549) cells (IC 50 =5.6 μM), while showing no...
Cancer is one of the major public health concerns in United States and other developed countries, affecting million deaths approximately every year worldwide. incidences show inconsistency between emerging nations. Epidemiologic findings intensely propose that incidence cancer are predisposed by environmental factors including diet, which essentially unavoidable. Strategies to prevent comprise overlapping approaches viz. Dietary prevention or chemoprevention. Naturally occurring constituents...
Samsum ant venom (SAV) is a rich repertoire of natural compounds with tremendous pharmacological properties. The present work explores its antineoplastic activity in different cell lines followed by confirmation vivo. lines, HepG2, MCF-7, and LoVo showed the differential dose-dependent effect an increased level significant cytokines, including Interleukin (IL)-1β, IL-6, IL-8 transcription factor, Nuclear factor-kappa B (NF-κB). However, was more effective on HepG2 MCF-7 cells than cells....
Background: Lung cancer is the primary cause of deaths worldwide. Thus, requisite for more coherent methods to lung therapy needed. Purpose: Chrysin (5, 7-dihydroxyflavone) a naturally occurring flavonoid having wide range pharmacological properties and commonly found in fruits, vegetables, honey propolis. In our study, we have hypothesized that chrysin would anticancer activity on L132 cell line.Methods: The cytotoxic effects were assessed by MTT NRU assay. DAPI was used evaluate death....
Multiple myeloma (MM) is a plasma cell malignancy that causes an accumulation of terminally differentiated monoclonal cells in the bone marrow, accompanied by multiple disease (MMBD). MM animal models have been developed and enable to interrogate mechanism tumorigenesis. However, these demonstrate little or no evidence MMBD. We try establish MMBD model with severe lesions easily accessible progression. 1 × 106 luciferase-expressing 5TGM1 were injected into 8–12 week-old NOD SCID gamma mouse...
Theoretically, each Sharp Edged Seat has fully open stem travel based on the port and ball diameters. Gas lift valve 1.5” 6 different diameters (3/16”, ¼”, 5/16”, 3/8”, 7/16” ½”). For diameter is usually larger than by 1/16”. Laboratory testing for sharp edged seats showed that actual flow area less theoretically calculated resulting from bellows stacking before reaches open. Consequently, restricts rate through declines. The purpose of this work to examine possibility improving efficiency...