Rajan Patel

ORCID: 0000-0002-3811-2898
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About
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Research Areas
  • Surfactants and Colloidal Systems
  • Protein Interaction Studies and Fluorescence Analysis
  • Ionic liquids properties and applications
  • Chemical and Physical Properties in Aqueous Solutions
  • Photochemistry and Electron Transfer Studies
  • Drug Transport and Resistance Mechanisms
  • Metal complexes synthesis and properties
  • Computational Drug Discovery Methods
  • Thermodynamic properties of mixtures
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Spectroscopy and Quantum Chemical Studies
  • Protein Structure and Dynamics
  • Antibiotics Pharmacokinetics and Efficacy
  • Analytical Chemistry and Chromatography
  • COVID-19 epidemiological studies
  • Nanoparticles: synthesis and applications
  • Collagen: Extraction and Characterization
  • Functional Brain Connectivity Studies
  • Nanomaterials for catalytic reactions
  • Neural dynamics and brain function
  • Lipid Membrane Structure and Behavior
  • Microscopic Colitis
  • Hemoglobin structure and function
  • Synthesis and biological activity

Jamia Millia Islamia
2016-2025

Newbury College
2022-2024

Ochsner Medical Center
2022-2024

Northwestern University
2023

Baylor College of Medicine
2023

Baylor University Medical Center
2023

Texas Children's Hospital
2023

University of California, San Diego
2023

Hudson Institute
2022

John Wiley & Sons (United States)
2022

In this study, pure CdO nanoparticles, magnetic Fe3O4 and Fe3O4-CdO nanocomposites were prepared via a solution combustion method using cetyltrimethylammonium bromide (CTAB) as template. These nanomaterial samples characterized by X-ray diffraction (XRD), ultraviolet-visible diffuse reflectance spectroscopy (UV-vis DRS), Fourier-transform infrared (FTIR), Raman spectroscopy, photoelectron microscopy (XPS), transmittance electron (TEM), scanning (SEM) analysis. XRD patterns confirmed the...

10.3390/catal14010071 article EN Catalysts 2024-01-17

Living cells do not interface naturally with nanoscale materials, although such artificial organisms can have unprecedented multifunctional properties, like wireless activation of enzyme function using electromagnetic stimuli. Realizing interfacing in a nanobiohybrid organism (or nanorg) requires (1) chemical coupling via affinity binding and self-assembly, (2) the energetic between optoelectronic states materials cellular process, (3) design appropriate interfaces ensuring biocompatibility....

10.1021/jacs.9b02549 article EN Journal of the American Chemical Society 2019-06-07

Noscapine is effective to inhibit cellular proliferation and induced apoptosis in nonsmall cell, lung, breast, lymphoma, prostate cancer. It also shows good efficiency skin cancer cells. In the current work, we studied mechanism of interaction between anticancer drug noscapine (NOS) carrier protein human serum albumin (HSA) by using a variety spectroscopic techniques (fluorescence spectroscopy, time-resolved fluorescence, UV–visible, fluorescence resonance energy transfer (FRET), Fourier...

10.1021/acs.molpharmaceut.8b00864 article EN Molecular Pharmaceutics 2019-01-10

The synergy between two different metals provides a dramatic enhancement in the bimetallic nanoparticles' catalytic properties since bimetallization improves associated with presence of individual metals. Therefore, herein, we reported facile, seedless, one-pot green synthesis Ag–Fe nanoparticles via reduction process using phytochemicals present Salvia officinalis aqueous extract. During Phyto-assisted nanofabrication nanoparticles, Ag+ and Fe3+ metal ions to NPs takes place according their...

10.1016/j.jmrt.2021.02.063 article EN cc-by-nc-nd Journal of Materials Research and Technology 2021-02-25

Coronavirus disease-2019 (COVID-19) is a global health emergency and the matter of serious concern, which has been declared pandemic by WHO. Till date, no potential medicine/ drug available to cure infected persons from SARS-CoV-2. This deadly virus named as novel 2019-nCoV coronavirus caused disease, that is, COVID-19. The first case SARS-CoV-2 infection in human was confirmed Wuhan city China. COVID-19 an infectious disease spread man well surface . In present work, silico approach...

10.1080/07391102.2020.1779131 article EN Journal of Biomolecular Structure and Dynamics 2020-06-22

This study was conducted to explore the interaction between two plant-based antiplasmodial compounds, gartanin and friedelin, bovine serum albumin (BSA). The objectives aimed elucidate binding characteristics, structural changes, thermodynamic parameters associated with interaction. Various methods were used including UV–vis, fluorescence, circular dichroism spectroscopy, supported by molecular docking dynamics simulation. results showed a concentration-dependent compounds BSA, revealing...

10.1021/acsomega.3c07630 article EN cc-by-nc-nd ACS Omega 2024-01-28

Recent work regarding the analysis of brain imaging data has focused on examining functional and effective connectivity brain. We develop a novel descriptive inferential method to analyze human using MRI (fMRI). assess relationship between pairs distinct regions by comparing expected joint marginal probabilities elevated activity voxel through Bayesian paradigm, which allows for incorporation previously known anatomical information. define two measures ascendancy. After assessing all voxels,...

10.1002/hbm.20182 article EN Human Brain Mapping 2005-08-09

Abstract Measures to decrease contact between persons during an influenza pandemic have been included in response plans. We used stochastic simulation models explore the effects of school closings, voluntary confinements ill and their household contacts, reductions contacts among long-term care facility (LTCF) residents on pandemic-related illness deaths. Our findings suggest that closings would not a substantial effect outcomes absence measures reduce out-of-school contacts. However, if...

10.3201/eid1304.060828 article EN cc-by Emerging infectious diseases 2007-04-01

The present work is a brief overview of the effect psychostimulant drug mephedrone hydrochloride (4MMC) on transport protein, bovine serum albumin (BSA). binding 4MMC BSA has been investigated by using UV-visible, steady-state fluorescence, time-resolved fluorescence resonance energy transfer, Fourier transform infrared, circular dichroism, and molecular docking method. 4-Methylmephedrone quenched intrinsic static quenching mechanism, which was further confirmed fluorescence. absorption...

10.1002/jmr.2734 article EN Journal of Molecular Recognition 2018-06-19

Herein, we are reporting the interaction of ionic liquid type gemini surfactant, 1,4-bis(3-dodecylimidazolium-1-yl) butane bromide ([C12-4-C12 im]Br2) with lysozyme by using Steady state fluorescence, UV-visible, Time resolved Fourier transform-infrared (FT-IR) spectroscopy techniques in combination molecular modeling and docking method. The steady fluorescence spectra suggested that was quenched [C12-4-C12 im]Br2 through static quenching mechanism as confirmed time spectroscopy. binding...

10.1002/bip.22647 article EN Biopolymers 2015-03-18

Herein, the binding of 1-methyl-3-octylimidazolium chloride [OMIM][Cl] ionic liquid with hen egg white lysozyme (HEWL) has been studied using fluorescence, time resolved UV-visible and circular dichroism (CD) spectroscopy, in combination computational study. The fluorescence results revealed that quenches fluorophore HEWL through static quenching mechanism. calculated thermodynamic parameters show bind hydrophobic interactions. In addition, negative value Gibbs energy change (∆G) indicates...

10.1080/07391102.2016.1204946 article EN Journal of Biomolecular Structure and Dynamics 2016-07-18

Abstract The present work reports the interaction of morpholinium based ionic liquid with transporter protein, human serum album (HSA). liquids cationic groups are reported to be comparatively less toxic than other such as imidazolium, pyridinium, piperidinium, pyrrolidinium etc. This highlight effect N‐butyl‐N‐methyl‐morpholinium bromide, [Mor1,4][Br] on structural stability HSA. was analyzed by using fluorescence, time resolved UV‐visible, CD spectroscopic techniques and molecular docking...

10.1002/slct.201601477 article EN ChemistrySelect 2017-01-23
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