A5061608383- Optical measurement and interference techniques
- Surface Roughness and Optical Measurements
- Advanced Measurement and Metrology Techniques
- 3D Printing in Biomedical Research
- Spectroscopy and Laser Applications
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Aluminum Alloy Microstructure Properties
- Advanced Measurement and Detection Methods
- Multiple and Secondary Primary Cancers
- Industrial Vision Systems and Defect Detection
- Periodontal Regeneration and Treatments
- Laser Design and Applications
- Genetic factors in colorectal cancer
- Pregnancy and preeclampsia studies
- Adhesion, Friction, and Surface Interactions
- Mesenchymal stem cell research
- Ultrasound Imaging and Elastography
- Acute Myeloid Leukemia Research
- Congenital Heart Disease Studies
- Nanoplatforms for cancer theranostics
- Polydiacetylene-based materials and applications
- Metal and Thin Film Mechanics
- Advanced ceramic materials synthesis
- Nanoparticle-Based Drug Delivery
- Metal Forming Simulation Techniques
National University of Singapore
1991-2024
East China University of Science and Technology
2021-2022
Kobe University
2019
174th hospital of the People's Liberation Army
2009
Southern Medical University
2006
Nanfang Hospital
2006
Stony Brook University
1987-1991
State University of New York
1988-1991
Gingiva plays a crucial barrier role at the interface of teeth, tooth-supporting structures, microbiome, and external agents. To mimic this complex microenvironment, an in vitro microphysiological platform biofabricated full-thickness gingival equivalents (gingiva-on-chip) within vertically stacked microfluidic device is developed. This design allowed long-term air-liquid culture, host-material interactions under flow conditions. Compared to static cultures, dynamic cultures on-chip enabled...
Magnetic nanoparticles (MNPs) are gaining much attention due to their applications in specialized fields, including diagnosis, bioimaging, drug delivery, and cell therapy. In recent years, the field of stem regenerative medicine comprising tissue engineering delivery has been powered by nanoparticles. Particularly, mesenchymal cells (MSCs) characterized with adequate immunomodulatory potential coupled an excellent ability that contributes improved therapy various diseases. For clinical MSCs,...
The realization of ultra-compact excimer lasers and the efficient cycling medium constitute a critical challenging issue that requires resolution. This study presents design an laser with no moving parts, featuring compact size lightweight construction, based on principles electrohydrodynamics (EHD). By employing adaptive cascaded Boltzmann convolution framework, innovative non-invasive velocity measurement method for is developed, characterized by its simplicity high precision. experimental...
The realization of ultra-compact excimer lasers and the efficient cycling medium constitute a critical challenging issue that requires resolution. This study presents design an laser with no moving parts, featuring compact size lightweight construction, based on principles electrohydrodynamics (EHD). By employing adaptive cascaded Boltzmann convolution framework, innovative non-invasive velocity measurement method for is developed, characterized by its simplicity high precision. experimental...
Developing physiologically relevant in vitro models for studying periodontitis is crucial understanding its pathogenesis and developing effective therapeutic strategies. In this study, we aimed to integrate the spheroid culture of periodontal ligament stem cells (PDLSCs) within a spheroid-on-chip microfluidic perfusion platform investigate influence interstitial fluid flow on morphogenesis, cellular viability, osteogenic differentiation PDLSC spheroids. spheroids were seeded onto device...
Abstract Regeneration of oral soft tissue defects, including mucogingival defects associated with the recession or loss gingival and/or mucosal tissues around teeth and implants, is crucial for restoring form, function, health. This study presents a novel approach using three‐dimensional (3D) bioprinting to fabricate individualized grafts precise size, shape, layer‐by‐layer cellular organization. A multicomponent polysaccharide/fibrinogen‐based bioink developed, parameters are optimized...
Abstract Bioelectricity has been a fundamental property of all living organisms. With electrical stimulation, cells can interact with their microenvironments, which makes stimulation highly beneficial for various biomedical applications. However, traditional mainly relies on bulky and complex equipment, may not be ideal due to the restriction movement, limited battery lifetime, uncomfortable wearing, potential unfriendly environment. The advent triboelectric nanogenerators (TENGs) helped...
Overexpression of Pokemon, which is an erythroid myeloid ontogenic factor protein, occurs in different cancers, including hepatocellular carcinoma (HCC). Pokemon also reported to have oncogenic activity various human cancers. This study investigated the effect knockdown on regulation HCC growth. POK shRNA suppressed expression protein HepG2 cells compared negative control vector-transfected cells. reduced cell viability and enhanced cisplatin-induced apoptosis AKT activation cycle-related...
Near-infrared conjugated polymer nanoparticles (NIR-CPNs) have been widely used in vivo imaging fields. However, most of them face the aggregation-induced fluorescence quenching (ACQ) dilemma and serious dye leakage behavior, which impedes long-term monitoring transplanted cells vivo. In present work, a novel strategy sandwich-type encapsulation interlayer crystalline SiO2 core + shell (SSiO2@SPFTBT@CSiO2) is developed, works well to avoid ACQ problem by homogeneously dispersing...
Abstract Background Intrauterine growth restriction (IUGR) leads to cardiac dysfunction and adverse remodeling of the fetal heart, as well a higher risk postnatal cardiovascular diseases. The rat model IUGR, via uterine artery ligation, is popular but its sequelae not investigated. Here, we performed an echocardiographic evaluation function determine how it can represent disease in humans. Methods Unilateral ligation was at embryonic day 17 (E17) echocardiography E19 E20. Results...
Objective To assess the clinical featmes of Peutz-Jeghers syndrome （PJS） and significance family survey. Methods Data PJS patients high risk relatives from 15 pedigrees, including manifestations endoscopic findings, were retrospectively studied. The diagnosed treated endoscopically or surgically followed up annually with gastroscopy, colonoscopy, barium swallow, abdominal uhrasonography chest X-ray. Results A total 63 screened 34 new confirmed by endoscopy, among whom, 18 had symptoms other...
Abstract Moire interferometry in this paper is extendedto topographic contour measurement of an arbi-trary object. The principle the proposed methodis different from that projection moire and shadowmoire methods both fringe formingmechanism w displacement evaluation.The advantage present method over oth-ers it has a very high sensitivity which canbe order ymm. As experimental verifi-cation, applied to topographiccontour cylindrical shell withand without diametric point loading. 1...
By using aoperiphery camera which is capable of 360° viewing we have extended the in-plane, shadow and reflection moire methods laser white light speckle to cylindrical surfaces without perspective effect.