A5084225304- Liver Disease Diagnosis and Treatment
- Acute Kidney Injury Research
- Cardiac, Anesthesia and Surgical Outcomes
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cancer, Hypoxia, and Metabolism
- Pulmonary Hypertension Research and Treatments
- Connective Tissue Growth Factor Research
- Metabolism and Genetic Disorders
- Adipose Tissue and Metabolism
- Gut microbiota and health
- Cardiovascular Function and Risk Factors
- Metabolomics and Mass Spectrometry Studies
- Biomarkers in Disease Mechanisms
- Cannabis and Cannabinoid Research
- Metabolism, Diabetes, and Cancer
- Thyroid Cancer Diagnosis and Treatment
- Dialysis and Renal Disease Management
- Thyroid Disorders and Treatments
- Lipid metabolism and disorders
- Chronic Kidney Disease and Diabetes
- Clostridium difficile and Clostridium perfringens research
Sun Yat-sen Memorial Hospital
2023-2025
Sun Yat-sen University
2023-2025
Huazhong University of Science and Technology
2011-2021
Union Hospital
2021
Hubei Provincial Center for Disease Control and Prevention
2021
University of Birmingham
2020
Wuhan Union Hospital
2020
The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation was introduced to estimate glomerular filtration rate (GFR) in chronic kidney disease (CKD) patients based on serum creatinine. CKD-EPI shows better accuracy compared with the current gold standard equation, Modification of Diet Renal (MDRD) but it has not been externally validated Chinese patients. This study original MDRD and two MDRD-based equations for estimating GFR 200 CKD 99m Tc-diethylenetriamine penta-acetate (...
Background Left ventricular (LV) diastolic dysfunction has been demonstrated to be an independent predictor of the future heart failure. Heart failure is one severe complications caused by overt hyperthyroidism. However, effects hyperthyroidism on are conflicting, and little known about prevalence risk factors in patients with Methods A total 388 were included compared age- gender- matched euthyroid control subjects. LV function was evaluated traditional tissue-Doppler echocardiography....
Abstract Background: Although 2-methylbutyrylcarnitine (2MBC) has been associated with metabolic disorders and promotes thrombosis, its effect on atherosclerosis remains elusive. This study was aimed at investigating the role of 2MBC in development. Methods Results: Apolipoprotein E-deficient (ApoE −/− ) mice were fed a Western diet for 18 weeks to induce atherosclerosis, then administered once-daily gavage or vehicle weeks. Parameters systemic lipid metabolism detected. did not upregulate...
Non-alcoholic steatohepatitis (NASH) is the progressive form of non-alcoholic fatty liver disease (NAFLD) which most common chronic worldwide. However, there are no FDA-approved drugs for treating NASH. The roles hypoxia-inducible factor-1α (HIF1α) playing in NASH not fully understood, and mainstream view that HIF1α knockout improved Here, order to explore clinical translation potential HIF1α, we used inhibitor KC7F2 treat diet-induced mice 10 weeks. Surprisingly, it turned out intensified...
Abstract Background: Hyperthyroidism heart disease (HHD) is the most severe complication of overt hyperthyroidism and increases mortality risk in affected patients. Early identification patients at a higher developing HHD could improve clinical outcomes through active surveillance management. Connective tissue growth factor (CTGF), secreted extracellular protein, plays significant role cardiac remodeling dysfunction. We aimed to investigate relationship between plasma CTGF level this study....