Kasia Adamczuk
A5048039060- Intracerebral and Subarachnoid Hemorrhage Research
- Lung Cancer Treatments and Mutations
- Acute Ischemic Stroke Management
- Atrial Fibrillation Management and Outcomes
- Intracranial Aneurysms: Treatment and Complications
- Cancer Genomics and Diagnostics
- Esophageal Cancer Research and Treatment
- Neurofibromatosis and Schwannoma Cases
- Antiplatelet Therapy and Cardiovascular Diseases
- Vascular Malformations Diagnosis and Treatment
- Neurosurgical Procedures and Complications
University of Edinburgh
2015-2025
Campbell Collaboration
2021
<h3>Importance</h3> The Restart or Stop Antithrombotics Randomized Trial (RESTART) found that antiplatelet therapy appeared to be safe up 5 years after intracerebral hemorrhage (ICH) had occurred during antithrombotic (antiplatelet anticoagulant) therapy. <h3>Objectives</h3> To monitor adherence, increase duration of follow-up, and improve precision estimates the effects on recurrent ICH major vascular events. <h3>Design, Setting Participants</h3> From May 22, 2013, through 31, 2018, this...
Background Symptomatic cerebral cavernous malformations are a rare sporadic or familial disease, which may cause haemorrhagic strokes epileptic seizures. In 2015, James Lind Alliance Priority Setting Partnership ranked targeted drug therapies as fourth of the top 10 research priorities for malformations. There no disease-modifying drugs malformations, but there several promising candidates with proof concept in human and animal studies. platform trials Objectives (1) Consolidate initiate...
Primary research question For adults surviving spontaneous (non-traumatic) symptomatic intracranial haemorrhage with persistent/paroxysmal atrial fibrillation/flutter (AF), does starting full treatment dose oral anticoagulation (OAC) result in a beneficial net reduction of all serious vascular events compared not OAC? Trial design Investigator-led, multicentre, randomised, open, assessor-masked, parallel group, clinical trial investigational medicinal product (CTIMP) prescribing strategies....