Yan Fang

ORCID: 0009-0009-6985-8236
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About
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Research Areas
  • Diabetes Treatment and Management
  • Plant-based Medicinal Research
  • Single-cell and spatial transcriptomics
  • Coronary Interventions and Diagnostics
  • Rabbits: Nutrition, Reproduction, Health
  • Meat and Animal Product Quality
  • Protease and Inhibitor Mechanisms
  • Cardiac electrophysiology and arrhythmias
  • Paraquat toxicity studies and treatments
  • Cerebrovascular and Carotid Artery Diseases
  • Cardiac Arrhythmias and Treatments
  • Traditional Chinese Medicine Studies
  • Animal Nutrition and Physiology
  • Chronic Kidney Disease and Diabetes
  • Acupuncture Treatment Research Studies
  • Immunotherapy and Immune Responses
  • interferon and immune responses
  • Renal Diseases and Glomerulopathies

Shanghai Jiao Tong University
2024

Harbin Medical University
2014

Sun Yat-sen University
2009

Inflammation plays a critical role in the development of atherosclerotic plaque, and lipopolysaccharide (LPS) is potentially important source inflammation. The aim this study was to develop rabbit model spontaneous thrombosis mimicking pathophysiological morphological characteristics plaque humans.The rabbits were randomized into four groups: group A (n=10) received normal diet; B regular diet weekly LPS injections (1 μg/kg, Escherichia coli); C (n=15) cholesterol-enriched before after...

10.5551/jat.22772 article EN cc-by-nc-sa Journal of Atherosclerosis and Thrombosis 2014-01-01

Abstract Dapagliflozin (DAPA) are clinically effective in improving diabetic nephropathy (DN). However, whether and how chromatin accessibility changed by DN responds to DAPA treatment is unclear. Therefore, we performed ATAC‐seq, RNA‐seq, weighted gene correlation network analysis identify the accessibility, messenger RNA (mRNA) expression, between clinical phenotypes mRNA expression using kidney from three mouse groups: db/m mice (Controls), db/db (case group), those treated with...

10.1002/cbf.3943 article EN Cell Biochemistry and Function 2024-02-20

Purpose: Alternative splicing and isoforms diversity have been confirmed with an important decisive role in the occurrence development of tumors. Our study aimed at further exploring relationship between factors among immune subpopulations molecular signatures AS uveal melanoma. Methods: Transcriptome sequencing Nanopore Illumina RNA 15 primary melanoma patient samples was performed. PCA clustering, Cibersort analysis, HRD cluster TCR TIDE analysis were used this to evaluate correlation...

10.2139/ssrn.4837918 preprint EN 2024-01-01

Abstract Objective: To observe the expression of Nav1·1 and effect electroacupuncture therapy (ET) on it after acute cerebral ischemia. Methods: Focal ischemic model was established by occluding right middle artery. One hundred forty-five male adult Sprague–Dawley rats were randomly divided into four groups: sham operation group, artery occlusion (MCAO) ET group riluzole group. Double immunofluorescence real-time PCR used to expression, TTC staining detect infarct volume at 6 hours, 1 day, 2...

10.1179/016164109x12445616596481 article EN Neurological Research 2009-08-24
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