A5093070064- Fermentation and Sensory Analysis
- Probiotics and Fermented Foods
- Viral gastroenteritis research and epidemiology
- Genomics and Phylogenetic Studies
- Bacteriophages and microbial interactions
- Animal Virus Infections Studies
- Fungal Biology and Applications
- Zoonotic diseases and public health
- Inflammatory Bowel Disease
- Biofuel production and bioconversion
- Mycorrhizal Fungi and Plant Interactions
- SARS-CoV-2 and COVID-19 Research
- Cytokine Signaling Pathways and Interactions
- Microbial infections and disease research
- Gut microbiota and health
- IL-33, ST2, and ILC Pathways
InSysBio (Russia)
2024-2025
Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
2025
Institute of Gene Biology
2023-2024
Bioinformatics Institute
2024
Viruses are ubiquitous across all kingdoms of cellular life, posing a significant threat to human health, and analyzing viral communities is challenging due their genetic diversity lack single, universally conserved marker gene. To address this challenge, we developed the AliMarko pipeline, tool designed streamline virus identification in metagenomic data. Our pipeline uses dual approach, combining mapping reads with reference genomes de novo assembly-based approach involving an HMM-based...
The concept of resistotype represents a new characterization bacterial communities distinct from their taxonomic composition. term “resistotype” is now commonly used to refer specific clusters within resistome that possess characteristic phenotypic profile, or set antimicrobial resistance genes. In contrast traditional approaches focus on individual genes manifestations resistance, analysis allows be considered at more comprehensive level, integrating different and interactions microbial...
Introduction Bats are considered the natural reservoirs of several viruses including coronaviruses (CoVs), two genera which, alpha- and betacoronaviruses, infect humans. Despite widespread screening bat samples for novel viruses, information on diversity in bats inhabiting Russian territory remains scarce. Here, we analyzed presence alphacoronaviruses (Alpha-CoVs) from European Russia. Methods Fourty three fecal 8 species: P. nathusii, kuhlii, M. brandtii, daubentonii, N. noctula, V....
Ganoderma lucidum exhibits the ability to synthesize a diverse range of biologically active molecules with significant pharmaceutical potential, including xylomannan and fucogalactan, which have demonstrated antitumor activity. However, there exists considerable intra-species variability in capacity produce these metabolites at high concentrations, likely reflecting genomic diversity observed from limited number strains sequenced date. We employed high-throughput shotgun sequencing obtain...
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Abstract Metagenomic sequencing is a valuable tool for studying viral diversity in biological samples. Analyzing this data complex due to the high variability of genomes and their low representation databases. We present Alimarko pipeline, designed streamline virus identification metagenomic data. A key feature our focus on interpretability findings: results are provided with tabular visual information help determine confidence level identified sequences. The pipeline employs two approaches...
<h3>Background</h3> The pathogenesis of Crohn's disease (CD) is considered from a multifactorial perspective with an undeniable contribution the genetic component. various ATG16L1 gene variants are strongly associated susceptibility to in different populations. It also known that cytokine profile as complex signature inflammatory process both locally and organism. aim study was assess local systemic L1 ileal CD patients clinical remission. <h3>Methods</h3> Serum samples, rectal tissue...