Sofia Ochkalova

ORCID: 0000-0003-2814-6012
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Genomics and Phylogenetic Studies
  • Probiotics and Fermented Foods
  • Distributed and Parallel Computing Systems
  • Microbial Community Ecology and Physiology
  • Fermentation and Sensory Analysis
  • Genetic diversity and population structure
  • Evolution and Genetic Dynamics
  • RNA and protein synthesis mechanisms
  • Insect symbiosis and bacterial influences
  • Legal, Health, Environmental and COVID-19 Challenges
  • Biofuel production and bioconversion
  • Environmental and Biological Research in Conflict Zones
  • Gut microbiota and health
  • Chromosomal and Genetic Variations
  • Microbial Metabolic Engineering and Bioproduction
  • Zoonotic diseases and public health

ITMO University
2021-2024

St Petersburg University
2023-2024

Institute of Gene Biology
2021-2022

The extant reptiles are one of the most diverse clades among terrestrial vertebrates and a few groups with instances parthenogenesis. Due to hybrid origin parthenogenetic species, reference genomes parental species as well progeny indispensable explore genetic foundations reproduction. Here, we report on first genome assembly rock lizard Darevskia valentini, paternal for several lineages. novel was used in reconstruction comprehensive phylogeny Squamata inferred independently from 7369 trees...

10.3390/genes13091569 article EN Genes 2022-09-01

Despite the recent advances in high-throughput sequencing, metagenome analysis of microbial populations still remains a challenge. In particular, metagenome-assembled genomes (MAGs) are often fragmented due to interspecies repeats, uneven coverage, and varying strain abundance. MAGs constructed via binning process that uses features input data order cluster long contigs presumably belonging same species. this work, we present BinSPreader-a refiner tool exploits assembly graph topology other...

10.1016/j.isci.2022.104770 article EN cc-by iScience 2022-07-19

Darevskia rock lizards include 29 sexual and seven parthenogenetic species of hybrid origin distributed in the Caucasus. All genus were formed as a result interspecific hybridization only four species. It remains unknown what are main advantages along with switching on reproduction evolution reptiles. Data whole transcriptome sequencing parthenogens their parental ancestors can provide value impact solving this problem. Here we have sequenced ovary tissue transcriptomes from unisexual lizard...

10.1016/j.dib.2021.107685 article EN cc-by Data in Brief 2021-12-01

The analysis of metagenomic data obtained via high-throughput DNA sequencing is primarily carried out by a dedicated binning process involving clustering contigs, presumably belonging to the same species. Here, we present protocol for improving quality using BinSPreader. We describe steps typical metagenome assembly and workflow. then detail refining, its variants, output, possible caveats. This optimizes reconstructing more complete genomes microorganisms that make up metagenome. For...

10.1016/j.xpro.2023.102417 article EN cc-by-nc-nd STAR Protocols 2023-07-04

Abstract Despite the recent advances in high-throughput sequencing, analysis of metagenome whole microbial population still remains a challenge. In particular, metagenome-assembled genomes (MAGs) are often fragmented due to interspecies repeats, uneven coverage and vastly different strain abundance. MAGs usually constructed via dedicated binning process that uses features input data order cluster contigs might belong same species. This has some limitations therefore binners discard shorter...

10.1101/2022.02.14.480326 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2022-02-15
Coming Soon ...