A5074773732- Amyloidosis: Diagnosis, Treatment, Outcomes
- Insect Resistance and Genetics
- Mass Spectrometry Techniques and Applications
- Bacillus and Francisella bacterial research
- Gut microbiota and health
- MicroRNA in disease regulation
- Gene expression and cancer classification
- Chemical Synthesis and Analysis
- Mitochondrial Function and Pathology
- Bone and Dental Protein Studies
- Tuberculosis Research and Epidemiology
- Infant Nutrition and Health
- Bacteriophages and microbial interactions
- Enzyme Structure and Function
- RNA modifications and cancer
- Bacterial Genetics and Biotechnology
- Drug Transport and Resistance Mechanisms
- Insect and Pesticide Research
- Thyroid Cancer Diagnosis and Treatment
- Autism Spectrum Disorder Research
- Metabolism and Genetic Disorders
- Craniofacial Disorders and Treatments
- Microbial Natural Products and Biosynthesis
- Neurological diseases and metabolism
- RNA and protein synthesis mechanisms
Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail
2024
Enterome (France)
2023
Microbiologie de l’alimentation au service de la santé
2017-2023
AgroParisTech
2020
Université Paris-Saclay
2020
ESPCI Paris
2018
Centre National de la Recherche Scientifique
2018
ParisTech
2018
Protéomique, Réponse Inflammatoire et Spectrométrie de Masse
2012-2014
Neuropathies are neurodegenerative diseases affecting humans and other mammals. Many genetic causes have been identified so far, including mutations of genes encoding proteins involved in mitochondrial dynamics. Recently, the "Turning calves syndrome", a novel sensorimotor polyneuropathy was described French Rouge-des-Prés cattle breed. In present study, we determined that this hereditary disease resulted from single nucleotide substitution SLC25A46, gene protein carrier family. This...
Abstract A network of RNA helicases, endoribonucleases and exoribonucleases regulates the quantity quality cellular RNAs. To date, mechanistic studies focussed on bacterial eukaryal systems due to challenge identifying main drivers decay processing in Archaea. Here, our data support that aRNase J, a 5′-3′ exoribonuclease β-CASP family conserved Euryarchaeota, engages specifically with Ski2-like helicase exosome potentially exert control over surveillance, at vicinity ribosome. Proteomic...
Abstract Bacillus cereus is responsible for foodborne outbreaks worldwide. Among the produced toxins, cereulide induces nausea and vomiting after 30 min to 6 h following consumption of contaminated foods. Cereulide, a cyclodepsipeptide, an ionophore selective K + in solution. In electrospray, selectivity reduced as [M Li] ; Na] NH 4 ] can also be detected without adding corresponding salts. Two forms are possible alkali‐cationized ions: charge‐solvated (CS) that exclusively dissociates by...
The gut microbiota is a considerable source of biologically active compounds that can promote intestinal homeostasis and improve immune responses. Here, we used large expression libraries cloned metagenomic DNA to identify able sustain an anti-inflammatory reaction on host cells. Starting with screen for NF-κB activation, have identified overlapping clones harbouring heterodimeric ATP-binding cassette (ABC)-transporter from Firmicutes. Extensive purification the clone’s supernatant...
BAG3 protein is an apoptosis inhibitor and highly expressed in Anaplastic Thyroid Cancer. We investigated the entire set of proteins modulated by silencing human anaplastic thyroid 8505C cancer cells using Stable-Isotope Labeling Amino acids Cell culture strategy combined with mass spectrometry analysis. By this approach we identified 37 up-regulated 54 down-regulated BAG3-silenced cells. Many these are reportedly involved tumor progression, invasiveness resistance to therapies. focused our...
Milk composition is complex and includes numerous components essential for offspring growth development. In addition to the high abundance of miR-30b microRNA, milk produced by transgenic mouse model miR-30b-mammary deregulation displays a significantly altered fatty acid profile. Moreover, wild-type adopted pups fed present an early defect.This study aimed investigate consequences feeding on duodenal development neonates, prime target suckled milk, along with comprehensive phenotyping.The...