A5059849089- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Metal-Organic Frameworks: Synthesis and Applications
- Magnetism in coordination complexes
- DNA Repair Mechanisms
- Genetic Syndromes and Imprinting
- Kruppel-like factors research
- Cancer Immunotherapy and Biomarkers
- Liver Disease and Transplantation
- Thyroid and Parathyroid Surgery
- Liver Disease Diagnosis and Treatment
- Metal complexes synthesis and properties
- Gastric Cancer Management and Outcomes
- Uterine Myomas and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Viral Infectious Diseases and Gene Expression in Insects
- Cancer-related molecular mechanisms research
- Carcinogens and Genotoxicity Assessment
- Endometriosis Research and Treatment
- MicroRNA in disease regulation
- Ferroptosis and cancer prognosis
- PARP inhibition in cancer therapy
- Polyoxometalates: Synthesis and Applications
- Molecular Sensors and Ion Detection
Ningbo No. 2 Hospital
2015-2024
Lanzhou University
2023
State Key Laboratory of Applied Organic Chemistry
2023
University of Chinese Academy of Sciences
2020-2022
Blood Center of Zhejiang Province
2020-2022
University of Duisburg-Essen
2010-2019
East China University of Science and Technology
2017-2018
Southeast University
2011
University of South Florida
2011
HBIS (China)
2011
Using data generated with cells exposed to ionizing-radiation (IR) in G
Abstract We previously reported that cells exposed to low doses of ionizing radiation (IR) in the G 2 -phase cell cycle activate a checkpoint is epistatically regulated by ATM and ATR operating as an integrated module. In this module, interphases exclusively with implement checkpoint, mainly using CHK1. The ATM/ATR module similarly regulates DNA end-resection at IR-doses. Strikingly, high IR-doses, coupling relaxes each kinase exerts independent contributions resection -checkpoint. DNA-PKcs...
MicroRNAs (miR) serve important roles in the development and progression of tumors by targeting different genes. miR-520a-3p reported lung breast cancers as a tumor suppressor gene. However, expression functional significance is not completely understood gastric cancer (GC). In present study, it was demonstrated that levels were significantly downregulated GC tissues cells using RT-qPCR. addition, associated with clinical stage invasion patients GC. Furthermore, overexpression inhibited cell...
An amino-functionalized terphenyl-tetracarboxylic acid, 2'-amino-[1,1':4',1″-terphenyl]-3,3″,5,5″-tetracarboxylic acid (H4tpta), was used as an adaptable linker to synthesize, under hydrothermal conditions, eight coordination polymers (CPs). The obtained products were formulated [Co(μ6-H2tpta)]n (1), [Co(μ3-H2tpta)(2,2'-bipy)]n (2), [M3(μ6-Htpta)2(2,2'-bipy)2]n (M = Mn (3), Cd (4)), [Ni2(μ4-tpta)(phen)2(H2O)4]n (5), [Zn2(μ6-tpta)(phen)2]n (6), {[Zn2(μ6-tpta)(μ-4,4'-bipy)]·H2O}n (7), and...
A pyridine-tricarboxylic acid, 5-(3',5'-dicarboxylphenyl)nicotinic acid (H3dpna), was employed as a adjustable block to assemble series of coordination polymers under hydrothermal conditions. The seven new were formulated [Co(μ3-Hdpna)(μ-dpey)]n·nH2O (1), [Zn4.5(μ6-dpna)3(phen)3]n (2), [Co1.5(μ6-dpna)(2,2'-bipy)]n (3), [Zn1.5(μ6-dpna)(2,2'-bipy)]n (4), [Co3(μ3-dpna)2(4,4'-bipy)2(H2O)8]n·2nH2O (5),[Co(bpb)2(H2O)4]n[Co2(μ3-dpna)2(H2O)4]n·3nH2O (6), and [Mn1.5(μ6-dpna)(μ-dpea)]n (7), wherein...
Abstract Background The purpose of this study was to explore the efficacy and safety high intensity focused ultrasound (HIFU) in gastric cancer with liver metastasis (GCLM) patients who were contraindicated for either hepatectomy or radiofrequency ablation (RFA). Methods This is a prospective, observational on GCLM 1–3 metastases. primary lesions thoroughly resected any case that exhibited extra-hepatic excluded. A 1:2:2 propensity score-matching analysis performed using logistic regression...
Left-sided colon cancer (LCC) and right-sided (RCC) have distinct characteristics in tumor immune microenvironment (TIME). Although existing studies shown a strong association between gene mutations TIME, whether the regulatory mechanisms TIME are different RCC LCC is still unclear. In this study, we showed fractions of CD8+ T cells were higher while those lower RCC. Besides, stronger was observed Specifically, using multi-omics data, demonstrated most top mutated genes (TMGs) including...
To explore the relationship of liver and spleen shear wave velocity in patients with cirrhosis combined portal hypertension, assess value predicting prognosis hypertension.All 67 diagnosed as hypertension by hepatic venous pressure gradient our hospital from June 2014 to December were enrolled into this study. The baseline information these was recorded. Furthermore, followed-up at 20 mo after treatment, measured acoustic radiation force impulse 1st week, 3rd month 9th treatment. Patients...
The aim of the present study was to assess performance contrast-enhanced ultrasound in distinguishing between malignant and benign breast lesions diagnostic value its clinical application. A total 52 cases with tumors 73 were included study. Time-intensity curves (TICs) for recorded, perfusion parameters obtained analyzed. Typical features irregular shape vascular morphology, uneven contrast agent distribution, filling defects retention, 'fast-out' wash-out mode, unclear boundaries internal...
is a member of the Kruppel-like factor, subfamily zinc finger proteins that are involved in cancers.
Drug-eluting beads transarterial chemoem-bolization (DEB-TACE) has the advantages of slow and steady release, high local concentration, low incidence adverse drug reactions compared to traditional TACE. DEB-TACE combined with sequentially ultrasound-guided radiofrequency ablation (RFA) therapy strong anti-cancer effects little side effects, but there are fewer related long-term studies until now.
Abstract Background RFA is designed to produce localized tumor destruction by heating the and surrounding liver tissue, especially suitable for patients who do not qualify hepatic resection. Many studies have reported that was inferior hepatectomy in treatment of recurrent colorectal metastases. However, strong evidence lacking literature. This study aimed investigate effect clinical outcome percutaneous ultrasound-guided repeat resection metastases after hepatectomy. Methods From January...
Cold in-place recycling (CIR) technology was used in rehabilitation of Nanhuan Road Handan city, China. A sequence tests performed on recycled materials with varied cement and water contents. The testing provides the necessary information to select a content for proper mix density optimum stability. Based this practice, study also presents life-cycle analysis asphalt pavement after rehabilitation. Five medium maintenance projects one overlay alternative are compared using them is recommended...
Effect of STAT3 decoy oligodeoxynucleotides (ODN) transduced by ultrasound microbubbles combined with on the growth esophageal squamous cell carcinoma and its mechanism were analyzed. EC9706 cells cultured in vitro divided into four groups: group E (ultrasound microbubble + irradiation), P (liposome C (ultrasound), CC microbubbles). Mutant ODNs used groups control was EC PC, respectively. Immunofluorescence assay flow cytometry to detect transfection efficiency each group. MTT colorimetric...
Gastric cancer (GC), as fifth most prevalent in the world, poses a serious threat to people's health, especially China and some undeveloped countries. If early warning or susceptible population screening for gastric can be achieved, its morbidity mortality will undoubtedly reduced. In this study, mutation of Lymphotoxin-alpha (LTA) gene rs909253 locus 200 samples 134 normal was completely detected via magnetic separation dual-color fluorescent genotyping method (MSFG), analyze correlation...
Contrast‑enhanced ultrasound (CEUS) and magnetic resonance imaging (MRI) were compared in evaluating the short‑term effects of microwave ablation (MWA) on uterine fibroids. A total 60 patients with fibroids treated by MWA enrolled experimental group during their two‑year follow‑up period according to inclusion criteria. Conventional two‑dimensional US, MRI CEUS performed determine volume reduction fibroid residue displaying size, echo signal intensity prior after treatment. As control group,...
Primary liver cancer (PLC) significantly affects the health of patients globally owing to its high morbidity and low survival rate. Radiofrequency ablation (RFA) has recently been introduced for clinical treatment PLC. However, significant immunosuppressive effects are induced by RFA, which limits application. This study aimed explore potential combination therapy with RFA investigating siRNAs against programmed death receptor 1 (PD-1) transforming growth factor-β (TGF-β) on antitumor effect...
Patients with type 2 diabetes mellitus (T2DM) commonly exhibit overlooked left ventricular and atrial hypertrophy. This research identifies potential risk factors intervention targets.