A5086206372- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Policy and Management
- Global Health Care Issues
- Economic and Environmental Valuation
- Healthcare cost, quality, practices
- Pharmaceutical Economics and Policy
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Frailty in Older Adults
- Gestational Diabetes Research and Management
- Neonatal Respiratory Health Research
- Total Knee Arthroplasty Outcomes
- Infant Development and Preterm Care
- Statistical Methods in Clinical Trials
- Orthopaedic implants and arthroplasty
- Health disparities and outcomes
- Nutrition and Health in Aging
- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Screening and Detection
- Biomedical Ethics and Regulation
- Bariatric Surgery and Outcomes
- Hip disorders and treatments
- Prostate Cancer Diagnosis and Treatment
- Birth, Development, and Health
- Anorectal Disease Treatments and Outcomes
- Quality and Safety in Healthcare
University of Auckland
2015-2024
University of Leeds
2008-2015
University of York
2012-2015
University of Alberta
2015
Leeds Teaching Hospitals NHS Trust
2012
Institute of Health Economics
2011
University of Birmingham
2010
Otago Polytechnic
2008
University of Sheffield
2002-2007
<h3>Importance</h3> Robotic rectal cancer surgery is gaining popularity, but limited data are available regarding safety and efficacy. <h3>Objective</h3> To compare robotic-assisted vs conventional laparoscopic for risk of conversion to open laparotomy among patients undergoing resection cancer. <h3>Design, Setting, Participants</h3> Randomized clinical trial comparing 471 with adenocarcinoma suitable curative conducted at 29 sites across 10 countries, including 40 surgeons. Recruitment was...
Treatment of gestational diabetes improves maternal and infant health, although diagnostic criteria remain unclear.
Background Neonatal hypoglycaemia is common, affecting up to 15% of newborns, and can cause brain damage. Currently, there are no strategies, beyond early feeding, prevent neonatal hypoglycaemia. Our aim was determine a dose 40% oral dextrose gel that will in newborn babies at risk. Methods Findings We conducted randomised, double-blind, placebo-controlled dose-finding trial buccal two hospitals New Zealand. Babies risk (infant mother with diabetes, late preterm delivery, small or large...
To compare the clinical and cost effectiveness of total hip arthroplasty with resurfacing in patients severe arthritis hip.Single centre, two arm, parallel group, assessor blinded, randomised controlled trial 1:1 treatment allocation.One large teaching hospital United Kingdom.126 older than 18 years joint, suitable for hip. Patients were excluded if they considered to be unable adhere procedures or complete questionnaires.Total (replacement entire femoral head neck); articular surface only,...
To evaluate the effectiveness of a web based decision aid versus leaflet versus, usual practice in reducing parents' decisional conflict for first dose MMR vaccination decision. The, impact on vaccine uptake was also explored.Three-arm cluster randomised controlled trial.Fifty GP practices north of, England.220 time parents making decision.Web, plus practice, only, (control).Decisional primary outcome and used as the, measure levels informed decision-making. secondary outcome.Decisional...
BACKGROUND: Prolonged postoperative ileus is a common major complication after abdominal surgery. Retrospective data suggest that doubles the cost of inpatient stay. However, current economic impact are based on retrospective studies rely clinical coding to diagnose ileus. OBJECTIVE: The aim this study was determine burden for patients undergoing elective colorectal DESIGN: Economic were audited from prospective database who underwent surgery at Auckland City Hospital between September 2012...
Background Neonatal hypoglycemia is common and can cause brain injury. Buccal dextrose gel effective for treatment of neonatal hypoglycemia, when used prevention may reduce the incidence in babies at risk, but its clinical utility remains uncertain. Methods findings We conducted a multicenter, double-blinded, placebo-controlled randomized trial 18 New Zealand Australian maternity hospitals from January 2015 to May 2019. Babies risk (maternal diabetes, late preterm, or high low birthweight)...
Background Robotic rectal cancer surgery is gaining popularity, but there are limited data about its safety and efficacy. Objective To undertake an evaluation of robotic compared with laparoscopic to determine safety, efficacy cost-effectiveness. Design This was a multicentre, randomised trial comparing resection in patients adenocarcinoma. Setting The study conducted at 26 sites across 10 countries involved 40 surgeons. Participants 471 Recruitment took place from 7 January 2011 30...
<h3>Importance</h3> Prophylactic oral dextrose gel reduces neonatal hypoglycemia, but later benefits or harms remain unclear. <h3>Objective</h3> To assess the effects on development of prophylactic for infants born at risk hypoglycemia. <h3>Design, Setting, and Participants</h3> Prospective follow-up a multicenter randomized clinical trial conducted in 18 Australian New Zealand hospitals from January 2015 to May 2019. Participants were late preterm term at-risk infants; those 9 centers (n =...
<b>Background:</b> An emergency care practitioner (ECP) is a generic drawn mainly from paramedic and nursing backgrounds. ECPs receive formal training extended clinical skills to equip them work as an integral part of the healthcare team working within across traditional boundaries unplanned care. Currently, are in different settings UK. <b>Objectives:</b> (1) To evaluate appropriateness, satisfaction cost compared with usual service available same setting, (2) increase understanding what...
Healthcare professional response rates to postal questionnaires are declining and this may threaten the validity generalisability of their findings. Methods improve do incur costs (resources) increase cost research projects. The aim these randomised controlled trials (RCTs) was assess whether 1) incentives, 2) type reminder and/or 3) reduced burden rates; implications such additional effective interventions. Two RCTs were conducted. In RCT A general dental practitioners (dentists) in...
BackgroundThe increasing prevalence of frailty with age is becoming a public health priority in countries ageing populations. Pre-frailty presents window opportunity to prevent the development community-dwelling older adults. This study aimed examine effectiveness complex intervention that combined nutrition-based and physical activity intervention, along each individually, reduce pre-frail adults over 2 years.MethodsIn this single-blind, x factorial, randomised, controlled trial, we...
Abstract Health economic evaluations are comparative analyses of alternative courses action in terms their costs and consequences. The Consolidated Economic Evaluation Reporting Standards (CHEERS) statement, published 2013, was created to ensure health identifiable, interpretable, useful for decision making. It intended as guidance help authors report accurately which interventions were being compared what context, how the evaluation undertaken, findings were, other details that may aid...
Abstract Background Hip replacement (arthroplasty) surgery is a highly successful treatment for patients with severe symptomatic arthritis of the hip joint. For older patients, several designs Total Arthroplasty have shown excellent results in terms both function and value money. However, younger more active there approximately 50% failure rate at 25 years traditional implants. resurfacing relatively new arthroplasty technique. In recent review literature on it was concluded that short-term...
The aim of fistula surgery is to eradicate the disease while preserving anal sphincter function. efficacy Surgisis® plug (Cook Medical, Bloomington, IN, USA) in treatment trans-sphincteric fistula-in-ano has been variably reported. To undertake a randomised comparison safety and Surgisis with surgeon's preference for fistulas. A randomised, unblinded, parallel-arm, prospective, multicentre clinical trial. Hospitals UK NHS involving colorectal surgeons accredited by Association Coloproctology...
Objectives Within cost-effectiveness models, prevalence figures can inform transition probabilities. The methodological quality of studies the choice but no single obvious candidate tool exists for assessing observational epidemiological selecting estimates. We aimed to compare different tools assess risk bias reporting prevalence, and develop possible numerical scoring systems using these set a threshold inclusion reports in an economic analysis neonatal hypoglycaemia. Design Assessments...