- RNA modifications and cancer
- Posttraumatic Stress Disorder Research
- Immune Cell Function and Interaction
- Cancer-related gene regulation
- Fungal Biology and Applications
- T-cell and B-cell Immunology
- Advanced Computational Techniques and Applications
- Plant Pathogens and Fungal Diseases
- Gold and Silver Nanoparticles Synthesis and Applications
- Cancer, Lipids, and Metabolism
- Cancer Cells and Metastasis
- Plant Ecology and Soil Science
- Cytokine Signaling Pathways and Interactions
- Cellular Mechanics and Interactions
- Hematopoietic Stem Cell Transplantation
- Treatment of Major Depression
- Natural product bioactivities and synthesis
- Information Architecture and Usability
- Point processes and geometric inequalities
- High-Temperature Coating Behaviors
- Medicinal Plants and Bioactive Compounds
- MRI in cancer diagnosis
- Bioactive natural compounds
- Nanofabrication and Lithography Techniques
- Medicinal Plant Pharmacodynamics Research
Sun Yat-sen University
2009-2025
Kunming Medical University
2025
Hubei University of Medicine
2020-2024
San Francisco VA Health Care System
2024
Neurological Surgery
2024
University of California, San Francisco
2024
Taihe Hospital
2023-2024
Heilongjiang University of Chinese Medicine
2024
Shanxi Academy of Medical Sciences
2024
Shanxi Medical University
2024
Antidepressant-like effects of ethanolic extract Hericium erinaceus (HE) mycelium enriched in erinacine A on depressive mice challenged by repeated restraint stress (RS) were examined. HE at 100, 200 or 400 mg/kg body weight/day was orally given to for four weeks. After two weeks administration, all except the control group went through with 14 days RS protocol. Stressed exhibited various behavioral alterations, such as extending immobility time tail suspension test (TST) and forced swimming...
Myocarditis, a health-threatening heart disease, is attracting increasing attention. This systematic study was conducted to the prevalence of disease through trends incidence, mortality, disability-adjusted life years (DALYs) over last 30 years, which would be helpful for policymakers better choices reasonable decisions.The global, regional, and national burdens myocarditis from 1990-2019 were analyzed by using 2019 Global Burden Disease (GBD) database. on produced new findings according...
Summary Cordyceps militaris chicken soup has always been one of the most popular Chinese‐style soups due to its high nutritional value and special flavour. In present work, C. was stewed after enzymolysis pretreatment. Several advanced techniques including GC ‐ MS , × TOF IMS were utilised investigate volatiles as‐prepared soup. analysis indicated that contents kinds main compounds especially aldehydes esters which have fatty sweet aroma in increased process. results demonstrated some...
Owing to the fragile ecological environment and prominent human–land conflict relationship, competition between land multifunctionality in karst region has increased. In this context, coordination stability of production–living–ecological space (PLES) have been severely affected, scientific diagnosis PLES characteristics can provide an important basis for optimizing national allocation. Using use data, study used a spatial measurement model examine temporal variations conflicts across...
Mesenchymal stem cells (MSCs) show promising therapeutic potential in treating inflammatory bowel disease (IBD), and intraperitoneal delivery of MSCs have become a more effective route for IBD treatment. However, the underlying mechanisms are still poorly understood. Here, we found that intraperitoneally delivered significantly alleviated experimental colitis. Depletion peritoneal B cells, but not macrophages, clearly impaired effects MSCs. Intraperitoneally improved likely by boosting...
Metastatic dormancy often refers to the stable cell cycle arrest of disseminated tumor cells (DTCs) at distant sites. However, whether circulating (CTCs) in blood microenvironment can enter a dormant state prior extravasation and becoming DTCs remains unclear. Using patient-derived melanoma CTC lines animal explant models (CDX), we identified previously unrecognized role cytoskeletal regulator cortactin (encoded by CTTN) controlling mTOR/p53-dependent senescence metastatic dormancy....
A novel, simple, and highly sensitive method was developed to detect the concentration of tyrosine-derived azo dye indirectly using silver nanocubes (AgNCs) as a substrate on super-hydrophobic film by surface-enhanced Raman spectroscopy (SERS). Diazotization-coupling reaction occurred between diazonium ions phenolic tyrosine, resulting in three new typical peaks SERS spectrum that formed AgNCs, indicating strong activity. Subsequently, limit detection this approach low 10−12 M for tyrosine....
To determine the effect of region interest (ROI) on tumor's apparent diffusion coefficient (ADC) and interobserver variability in thyroid nodules. Thirty-three individuals with 45 pathologically-confirmed nodules were assessed by preoperative diffusion-weighted imaging (DWI) b values 0 400 s/mm2, respectively. Two readers evaluated ADC lesions based three ROI techniques: whole-volume, single-slice small solid-sample groups. Interobserver was analyzed for all techniques, mean ADCs benign...
This study aimed to assess the toxicity of ammonia on clam Cyclina sinensis and post-exposure recovery. With increased exposure TAN, alkaline phosphatase (AKP) activities after showed a trend growing initially subsequently decreasing, whereas AKP recovery an increasing trend. The were significantly higher than those in control. acid (ACP) T1 T2 control, ACP T3, T4, T5 lysozyme (LZM) LZM lower Overall, clams exposed low level TAN (≤ 40 mg/L) can recover normal levels completely. However, 48h...
Suppressor of cytokine signaling 3 (SOCS3) plays an important role in mice fetal liver erythropoiesis, but the roles SOCS3 human hematopoietic stem cells (HSCs) have not been well investigated. In present study, lentiviral small interference RNA expression vectors (shRNA) were constructed and stably transferred into HSCs. We found that knockdown induced erythroid expansion Conversely, Ectopic progenitor blocked colony formation To further explore involved mechanism, we compared gene profiles...
The transient photothermal process of gold nanoparticles (AuNP) capped with different molecules, namely, citrate, cetyltrimethylammonium bromide (CTAB), and methoxyl-polyethylene glycol thiol (mPEG), has been investigated by time-resolved infrared emission spectroscopy monitored a step-scan Fourier-transform spectrometer. Upon photoexcitation the surface plasmonic resonance band AuNPs 532 nm nanosecond pulsed laser, was observed within about 1 μs, referring to duration laser heating...
In this study, a sandwich structure (silicon/polymer/silicon) was prepared to demonstrate the adhesion strength between polymer and silicon layers using four-point bending system. For first time, stealth dicing (SD) method applied layer generate an initial crack, SD compared with traditional of forming trench by blade dicing. From experimental results, improved test yield showed lower level sudden force drop. As result, is highly reliable way measure
<title>Abstract</title> Due to its dynamic nature and the absence of reliable real-time monitoring tools, predicting chronic graft-versus-host disease (cGVHD) progression was challenging. This caused a significant investment both time financial resources ensure good management cGVHD. In response this challenge, we identified distinct B-cell subpopulation characterized by CD27<sup>+</sup>CD86<sup>+</sup>CD20<sup>-</sup>, which could precisely distinguish cGVHD from healthy donors. Leveraging...