A5044903742- Diabetes and associated disorders
- Pancreatic function and diabetes
- Diabetes Management and Research
- Natural product bioactivities and synthesis
- Vibrio bacteria research studies
- Virus-based gene therapy research
- Cancer-related molecular mechanisms research
- Salmonella and Campylobacter epidemiology
- Traditional Chinese Medicine Analysis
- Metabolomics and Mass Spectrometry Studies
- Growth Hormone and Insulin-like Growth Factors
- Liver Diseases and Immunity
- Trace Elements in Health
- Phytochemical compounds biological activities
- Pharmacological Effects of Natural Compounds
- Plant biochemistry and biosynthesis
- Phytochemical Studies and Bioactivities
- Escherichia coli research studies
- interferon and immune responses
- Flavonoids in Medical Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Phytochemistry and Bioactive Compounds
- Analytical Chemistry and Chromatography
- Osteomyelitis and Bone Disorders Research
- Salivary Gland Disorders and Functions
Guangxi Medical University
2011-2025
Stomatology Hospital
2017-2025
Chinese People's Liberation Army
2025
State Key Laboratory of Kidney Diseases
2025
National Clinical Research Center for Digestive Diseases
2025
First Affiliated Hospital of Xinjiang Medical University
2025
Xinjiang Medical University
2025
Qingdao Women and Children's Hospital
2020-2024
Sichuan University
2024
West China Hospital of Sichuan University
2024
Abstract Clinical and environmental Vibrio cholerae organisms collected from February 2004 through April 2005 were systematically isolated 2 rural Bangladeshi locales. Their genetic relatedness was evaluated at 5 loci that contained a variable number of tandem repeats (VNTR). The observed minimal overlap in VNTR patterns between the communities consistent with sequential, small outbreaks local sources.
Postoperative wound healing is an important part of the success dental implant surgery. However, in case complex surgery or unfavorable factors, often unsatisfactory.The aim this study was to explore effects vitamin C supplementation healing, following placement implants with without bone grafts and patients chronic periodontitis.This randomized controlled clinical trial included 128 requiring replace missing teeth. Patients were divided into four groups, group A received supported by guided...
Two new phenolic compounds, epicaesalpin J and 7,10,11-trihydroxydracaenone, were isolated from the heartwood of Caesalpinia sappan L. Their structures identified by spectroscopic analysis methods, such as 1D 2D NMR, along with high resolution mass spectral data. The NO inhibition activities two compounds six known tested.
By conventional genetic methods, including pulse-field gel electrophoresis and multilocus sequence typing, most pathogenic, cholera toxin-positive O1 O139 isolates of Vibrio cholerae cannot be distinguished. We evaluated relationships among 173 V. collected between 1992 2007 from different geographic areas in India by analyzing five variable number tandem repeat (VNTR) loci. Each VNTR locus was highly variable, with 5 19 alleles. eburst analysis revealed four large groups genetically related...
Abstract Background and Objective Although periimplantitis periodontitis share similar features, particularly clinical they are two different diseases should be analyzed separately. Thus far, few omics‐level differences in have been reported. This study was aimed at exploring the differential effects of expression mRNAs, lncRNAs, miRNAs by high‐throughput sequencing competitive endogenous RNA (ceRNA) analysis. Methods Gingival tissues healthy individuals (HI) (PI) (P) patients were collected...
O-antigen biosynthetic (wbf) regions for Vibrio cholerae serogroups O5, O8, and O108 were isolated sequenced. Sequences compared to those of other published V. regions. These wbf showed a high degree heterogeneity both in gene content order. Genes identified frequently greater similarities polysaccharide biosynthesis genes from species than cholerae. Our results demonstrate the plasticity cholerae, diversity genetic pool which they are drawn, likelihood that new pandemic will emerge.
The aim of this study was to investigate the effectiveness a high-dose zinc sulfate and low-dose D-penicillamine combination in treatment pediatric Wilson's disease (WD). A retropective chart review 65 patients with WD conducted. These received (8-10 mg/kg/day) as primary treatment. dose elemental is 68-85 mg/day until 6 years age, 85-136 8 136-170 10 age then 170 mg/day, 3 divided doses 1 h before meals. After clinical biochemical improvement or stabilization, alone administered maintenance...
<title>Abstract</title> <bold>Background: </bold>Insufficient keratinized mucosais one of the biological complications in patients undergoing jaw reconstruction, and its management has rarely been reported. The reported cases mucosareconstruction edentulous implant restoration are limited, with a scarcity histological data on soft tissue healing process, leading to low correlation between reports. <bold>Case presentation: </bold>This report presents documented case provides, for first time,...
Nine new triterpene saponins, ilekudinosides K−S (1−9), and eight known saponins were isolated from the 70% ethanol extract of leaves Ilex kudingcha. The characterized as 3-O-α-l-rhamnopyranosyl(1→2)-β-d-glucopyranosyl-α-kudinlactone (1), 3-O-β-d-glucopyranosyl(1→3)-α-l-arabinopyranosyl-β-kudinlactone (2), 3-O-α-l-rhamnopyranosyl(1→2)-α-l-arabinopyranosyl-γ-kudinlactone (3), 3-O-β-d-glucopyranosyl(1→2)-β-d-glucopyranosyl-α-kudinlactone (4),...
This study describes the anatomical, light microscopic, and ultrastructural characterization of immune organs in ostrich chicks. In this 6 healthy 8-week-old chicks were processed for transmission electron microscopy. Hematoxylin eosin as well improved Weigert staining used The small thymus, which clustered caudally along both sides neck, contained Hassall's corpuscles medulla. cloacal bursa, formed hanging lateral walls cloaca, enveloped cloaca but did not form a truly independent bursa....
Type 1 diabetes is an autoimmune disorder, which occurs due to β cell damage. Interleukin (IL)-10, a pleotropic cytokine, has been reported have anti‑inflammatory, immunosuppressive and immunostimulatory properties. Administration of IL‑10 known prevent in non‑obese diabetic (NOD) mice. However, the mechanism IL‑10‑induced protection NOD mice requires further investigation. The aim present study was evaluate protective effect transgenic expression pancreatic cells against damage elucidate...
Abstract Pancreatic β‐cell damage mediated by apoptosis is believed to be a main trigger of type 1 diabetes mellitus (T1DM), which proposed as an organ‐specific autoimmune disease T cells. Nonetheless, the fundamental origins T1DM remain uncertain. Here, we illustrate that increase in PLAGL1 expression induces apoptosis, evidenced mitochondrial membrane impairment and nucleolar degradation. The gene levels from cDNA samples were determined using qRT‐PCR method. Western blot...
The diagnosis and treatment of small-bowel diseases is clinically difficult. purpose this study was to evaluate the diagnostic therapeutic value double-balloon enteroscopy in diseases.The history outcomes 2806 patients who underwent from July 2004 April 2017 were reviewed, which included 562 with obscure digestive tract bleeding, 457 diarrhea, 930 abdominal pain, 795 weight loss, 62 intestinal obstruction. Examinations performed through mouth and/or anus according clinical symptoms images....
The aim of the present study was to provide an animal experimental basis for protective effect adenoviral vector-mediated interleukin-10 (Ad-mIL-10) gene on islet β‑cells during early stages type 1 diabetes (T1D) in non‑obese diabetic (NOD) mice. A total 24 female NOD mice at onset were allocated random into three groups (n=8 per group): Group 1, intraperitoneally injected with 0.1 ml Ad‑mIL‑10; group 2, adenovirus vector; and 3, a control. In addition 2 8 age‑ gender‑matched PBS assigned 4...
To investigate the features and treatment status of children with type 1 diabetes mellitus (T1DM) in China.
Tanshione IIA (TSN) is the major active component of Salvia miltiorrhiza, a traditional Chinese Medicine. TSN protects against antioxidant-induced liver injury, although exact mechanism not well understood.In this study, protective effects was examined by enzyme-linked immunosorbent assay (ELISA) and histochemistry several cytokines.TSN found to significantly reduce plasma alanin aminotransferase aspartate amino transferase levels in mice with concanavalin A-induced immune-mediated injury....
Three new triterpene saponins, ilekudinosides T-V (1-3), along with six known saponins were isolated from the 70% ethanolic extract of leaves Ilex kudingcha. The characterized as 3-O-beta-d-glucopyranosyl-(1 --> 3)-[alpha-l-rhamnopyranosyl-(1 2)]-alpha-l-arabinopyranosyl-3beta,19alpha-dihydroxy-urs-12(13)-en-28,20beta-lactone (1), 2)]-alpha-l-arabinopyranosyl-3beta,19alpha-dihydroxy-12-ethoxy-urs-13(18)-ene-28,20beta-lactone (2),...
BackgroundIn an attempt to better understand the non-O1/O139 isolates of Vibrio cholerae, a systematic study clinical and environmental collected from various geographical locations between years 1932 1998 was conducted.MethodsNinety-nine V. cholerae sources regions were studied by sequencing seven housekeeping genes. Genetic relatedness defined multiple methods that allow for observed high levels recombination.ResultsFour subpopulations determined. One subpopulation contained mostly...