A5100327258- Liver Disease Diagnosis and Treatment
- Ophthalmology and Visual Impairment Studies
- Ovarian cancer diagnosis and treatment
- Glaucoma and retinal disorders
- MicroRNA in disease regulation
- Endometrial and Cervical Cancer Treatments
- Corneal surgery and disorders
- Cancer Mechanisms and Therapy
- Neurological Disease Mechanisms and Treatments
- Neurological Disorders and Treatments
- Kidney Stones and Urolithiasis Treatments
- Ferroptosis and cancer prognosis
- Renal Diseases and Glomerulopathies
- Cancer-related molecular mechanisms research
- ECG Monitoring and Analysis
- Alzheimer's disease research and treatments
- Adipose Tissue and Metabolism
- Endometriosis Research and Treatment
- Endoplasmic Reticulum Stress and Disease
- Cervical Cancer and HPV Research
- Cancer, Hypoxia, and Metabolism
- Pleural and Pulmonary Diseases
- Heart Rate Variability and Autonomic Control
- Lung Cancer Diagnosis and Treatment
- Coronary Interventions and Diagnostics
Sun Yat-sen University
2024
Integrated Chinese Medicine (China)
2024
Shandong Provincial Hospital
2012-2023
Shandong First Medical University
2020-2023
Shandong University
2012-2023
Guangdong Provincial Hospital of Traditional Chinese Medicine
2023
Taizhou First People's Hospital
2022-2023
Central Hospital of Zibo
2014-2023
Lanzhou University of Technology
2023
Institute of Modern Physics
2023
Epidemiological studies of mild cognitive impairment (MCI) and subtypes MCI have rarely focused on rural residents in China.This population-based study included 5068 participants (age ≥60 years) who were living communities. We defined MCI, amnestic (aMCI), non-amnestic (naMCI) following the Petersen's criteria that integrated neuropsychological assessments with in-person clinical evaluations.The overall prevalence aMCI, naMCI was 26.48%, 22.30%, 4.18%, respectively. The increased age....
Cervical cancer screening is an effective method for reducing the incidence and mortality of cervical cancer, but attendance rate in developing countries far from satisfactory, especially rural areas. Wufeng a region high China. This study aimed to investigate issues that concern factors affect women's willingness undergo area.A cross-sectional survey women was conducted determine their knowledge about screening, demographic characteristics barriers screening.Women who were willing...
<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> The purpose of this paper is to propose a new algorithm for T-wave end location in electrocardiograms, mainly through the computation an indicator related area covered by curve. Based on simple assumptions, essentially concavity form, it formally proved that maximum computed inside each cardiac cycle coincides with end. Moreover, robust acquisition noise, wave form morphological variations and...
To describe longitudinal changes in corneal curvature (CC) and axial length (AL) over 14 years, to explore the relationship between AL CC, length/corneal radius (AL/CR) ratio.
Purpose To evaluate the value of C1QC + and SPP1 TAMs gene signatures in patients with cervical cancer. Methods We compare M1/M2 at single cell level bulk RNA-seq which signature can clearly divide cancer into distinct clinical subclusters better. Results At single-cell level, signatures, but not M1 M2 could divided two a colon data set an advanced basal set. For from TCGA, high low have best prognosis, lowest proportion (34.21%) locally (LACC), highest immune infiltration, whereas worst...
Rodents respond to chronic high fat diet in at least two ways: some of them may readily gain body weight and become obese (termed obesity-prone, OP), others not obesity-resistant, OR). Transcriptomic metabonomic profiling OP OR rats has been conducted, showing sets significantly different phenotypic profiles response 16 weeks diet. We observed significant differences transcriptional expression nearly 80 genes, which are known be involved lipid metabolism, transport, ketone production. The...
ObjectiveNeoadjuvant chemotherapy (NACT) for cervical cancer still remains controversial. NACT was evaluated to establish selection criteria.MethodsA matched-case comparison designed the group (n = 707) and primary surgery treatment (PST; n investigate short-term responses high/intermediate risk factors (HRFs/IRFs). The 5-year disease-free survival (DFS) overall (OS) rates were stratified by response, HRFs/IRFs, International Federation of Gynecology Obstetrics (FIGO) stage tumour size,...
Background and objectives Formation progression of atherosclerotic vulnerable plaque (VP) is the primary cause many cardio-cerebrovascular diseases such as acute coronary syndrome stroke. It has been reported that bone marrow mesenchymal stem cells (MSC) exhibit protective effects against kinds including myocardial infarction. Here, we examined intravenous MSC infusion on a VP model provide novel evidence its influence therapy in this animal disease model. Subjects methods Thirty healthy...
Cardiovascular risk factors and related disorders are common among older adults, use of various classes cardiovascular (CV) drugs could reduce the disease (CVD). However, data sparse with regard to CV rural-dwelling adults in China. Therefore, this population-based study aimed describe living rural communities China, while taking into account for primary secondary prevention CVDs. This included 5,246 participants (age ≥65 years; 57.17% women; 40.68% illiteracy) baseline examination...
Gastric cancer (GC) is one of the most lethal forms due to absence tools for its early detection. Here, we explored critical biomarkers diagnosis.Key in serum from patients with gastric (EGC) and healthy controls (HCs) were identified via mass spectrometry expression inter-alpha-trypsin inhibitor heavy chain 4 (ITIH4) was evaluated using several methods. Furthermore, ITIH4 sera exosomes EGC, advanced GC (AGC), low grade intraepithelial neoplasia (LGN), chronic superficial gastritis...
Little is known about whether nonalcoholic fatty liver disease (NAFLD) associated with dementia or the role of serum proinflammatory cytokines in association. We aimed to investigate interrelationships NAFLD, cytokines, and among rural-dwelling older adults.This population-based cross-sectional study included 5129 participants (aged ≥60 years; 61.79% women) who were living rural communities examined March 2018-September 2018. NAFLD was defined through transabdominal ultrasound examination...
Aldehyde dehydrogenase 5 family, member A1 (ALDH5A1) belongs to the superfamily of aldehyde dehydrogenases (ALDHs). However, prognostic value ALDH5A1 in ovarian cancer remains unclear. The aim this study was explore relationship between and prognosis patients with (OC). We compared expression OC that innormal controls, using GSE40595 profiling data. Tissue microarray analysis conducted for192 patients, 14 adjacent normal ovary tissues, 2 tissues. Using "Kaplan-Meier plotter" (KM plotter)...
D-ribose levels are demonstrated to be increased in type II diabetes mellitus and blood is involved the development of diabetic complications such as encephalopathy nephropathy. However, mechanism mediating pathogenic role nephropathy remains poorly understood. Given that was reported induce advanced glycation end products (AGEs) formation, present study tested whether induces NLRP3 activation associated glomerular injury via AGEs/ receptor AGEs (RAGE) signaling pathway. In vivo, C57BL/6J...
Abstract Purpose To evaluate the association between outdoor and nearwork activities at baseline myopia stabilisation by age 15 in C orrection of M yopia E valuation T rial ( COMET ). Methods enrolled 469 children (ages: 6–11 years) with spherical equivalent − 1.25 4.50 D, who were randomised to progressive addition or single vision lenses followed for 5 years their original lenses. At baseline, families recorded child's 3 days within a week. Weekly hours spent calculated each participant....
BACKGROUND: Our study was designed to improve the accuracy of determining whether pulmonary nodules are benign or malignant.We evaluated clinical and imaging features serum markers: neuron specific enolase (NSE), carcino-embryonic antigen (CEA), cytokeratin fragment 21-1 (CYFRA 21-1), miRNA-21-5p, miR-574-5pof in 39 patients with pathology information. Factors that differed significantly between those versus malignant were used establish a prediction model for identifying nodules.The...
The purpose of this article is to evaluate optic nerve head (ONH) characteristics in an ethnically diverse cohort young U.S. adults.In study, 409 myopes and 206 nonmyopes (median age 22 years) completed measures including biometry spectral domain optical coherence tomography from enface (ovality torsion) cross-sectional (tilt crescent width) scans. Associated factors were evaluated using multivariable models.In myopic versus nonmyopic right eyes, median tilt (6.0° vs. 2.4°; P < 0.0001)...
Ovarian cancer is a severe health threat for women with increased incidence and stymied development in diagnosis therapy. Drug resistance still big challenge. Bufalin multi-functional steroid-like compound extracted from natural product Chansu has been tested as antitumour agent recently. The application mechanism of bufalin ovarian remain unclear yet. was first examined epithelial cell well primary tissue to evaluate its inhibitory activity growth migration, followed by the validation...