A5026611922- Drug-Induced Adverse Reactions
- Peripheral Neuropathies and Disorders
- Immunodeficiency and Autoimmune Disorders
- Vasculitis and related conditions
- CNS Lymphoma Diagnosis and Treatment
- Hereditary Neurological Disorders
- Ocular Diseases and Behçet’s Syndrome
- Multiple Sclerosis Research Studies
- Antimicrobial Resistance in Staphylococcus
- Autoimmune Neurological Disorders and Treatments
- Renal Diseases and Glomerulopathies
- Retinal and Optic Conditions
- Autoimmune Bullous Skin Diseases
- Intramuscular injections and effects
- Photography and Visual Culture
- Fungal Infections and Studies
- Neurological and metabolic disorders
- Cancer Immunotherapy and Biomarkers
- Chemotherapy-related skin toxicity
- Antifungal resistance and susceptibility
- Brain Metastases and Treatment
- Visual Culture and Art Theory
- Antibiotic Use and Resistance
- Cardiac electrophysiology and arrhythmias
- Pharmacovigilance and Adverse Drug Reactions
Royal North Shore Hospital
2020-2024
The University of Sydney
2022-2023
Nationwide Children's Hospital
2023
University of Mississippi Medical Center
2020
State Street (United States)
2020
American College of Allergy, Asthma and Immunology
2020
John Hunter Hospital
2018
To localize the sites and determine extent of human rhinovirus (HRV) replication in upper respiratory tract, biopsies nasal nasopharyngeal epithelia were collected from 26 HRV-or 7 sham-inoculated volunteers on days 1, 3, 5 12, 20, or 33 after inoculation analyzed by situ hybridization. HRV-infected cells detected at least 1 day 22 23 subjects who developed a cold had secretions positive for picornavirus polymerase chain reaction. Low numbers hybridization-positive ciliated present biopsies....
Increasing implementation of the highly efficacious immune checkpoint inhibitors (ICIs) has raised awareness their various complications in form immune-related adverse events (irAEs). Transverse myelitis following ICIs is thought to be a rare but serious neurologic irAE and knowledge limited about this distinct clinical entity.
Susac's syndrome is a rare and debilitating disease characterized by the triad of encephalopathy, branch retinal artery occlusions, sensorineural hearing loss. All manifestations may not be clinically apparent at presentation resulting in delayed diagnosis. Early recognition prevent sequelae such as permanent cognitive, visual, We present case that was also refractory to conventionally prescribed combination immunosuppressive treatments including high-dose potent corticosteroids, intravenous...
Successful vaccination has been the decisive factor in overall decline of SARS-CoV2 infection related morbidity and mortality. However, global effects COVID-19 pandemic are ongoing, with reports glomerular disease occurring relation to both vaccination. A particular rise anti-GBM identified. Information is still emerging regarding optimal management such cases. We reviewed antibody detection rates at our test center over past 5 years. followed three patients biopsy confirmed temporally Each...
Endovascular procedures are standard of care for an increasing range cerebrovascular diseases. Many endovascular devices contain plastic and coated with a hydrophilic polymer which has been rarely described to embolize, resulting in distal granulomatous inflammatory lesions within the vascular territory.We reviewed three cases cerebral reactions that occurred after intervention internal carotid aneurysms. The patient procedure details, presentation, relevant investigations, treatment course...
Late-onset combined immunodeficiency (LOCID), considered now a subset of common variable (CVID) disorders, is characterized by predominantly T-cell immune defect. LOCID has distinct phenotype from CVID with greater risk lymphoproliferative complications. As compared to the cohort, patients also have increased rates splenomegaly and granulomatous disease. We report case central nervous system (CNS) lymphoma in 67-year-old male as presenting manifestation LOCID. The patient achieved complete...
<h3>Objectives</h3> Acute neuronitis secondary to COVID-19 vaccines has been seldom reported, mostly involving the brachial plexus. We present two cases of and lumbosacral plexitis following AstraZeneca (AZ) vaccine in patients on immunotherapy for Multiple Sclerosis (MS). <h3>Methods Results</h3> A 51-year old female with a 12 month history MS natalizumab, received second AZ vaccination June 2021. The next day she developed left shoulder pain lower limb weakness. plexus MRI demonstrated...
Tumefactive demyelinating lesions (TDLs) are defined as >2 cm on MRI of the brain. They identified in a range diseases including massive demyelination due to Marburg's acute MS, Schilder's Disease, Balo's concentric sclerosis, and MS. Apart from rare variants which often diagnosed histologically, there no detailed data phenotype TDLs.We describe clinical radiological features four similar patients with very large TDLs (>4 cm), that not consistent may represent distinct phenotype.All...
<h3>Objectives</h3> Apart from the rare demyelinating variants of Marburg's acute MS, Schilder's Disease, and Balo's concentric sclerosis, there are no detailed data to phenotype tumefactive lesions (TDLs), aside being greater than 2cm on MRI. We identified similar clinical radiological features 4 patients with TDLs that may represent a distinct phenotype. Our primary objective was describe details these patients, secondary objectives literature review treatment recommendations....