A5049658917- Silicon Carbide Semiconductor Technologies
- 3D Surveying and Cultural Heritage
- Masonry and Concrete Structural Analysis
- Semiconductor Quantum Structures and Devices
- Near-Field Optical Microscopy
- Semiconductor materials and devices
- Medieval Architecture and Archaeology
- Silicon and Solar Cell Technologies
- Building materials and conservation
- Quantum Dots Synthesis And Properties
- Semiconductor materials and interfaces
- Lysosomal Storage Disorders Research
- Autoimmune Bullous Skin Diseases
- Psoriasis: Treatment and Pathogenesis
- Dermatology and Skin Diseases
- Spondyloarthritis Studies and Treatments
- Cancer Cells and Metastasis
- Thin-Film Transistor Technologies
- Cutaneous Melanoma Detection and Management
- Copper Interconnects and Reliability
- Urban Planning and Valuation
- Ancient Mediterranean Archaeology and History
- Structural Analysis of Composite Materials
- Structural Engineering and Vibration Analysis
- Research on Leishmaniasis Studies
University of Palermo
2014-2023
Polytechnic University of Turin
2007-2023
Marconi University
2020
Central Michigan University
2020
Michigan United
2020
Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo
2016-2019
Azienda Socio Sanitaria Territoriale della Valtellina e Alto Lario
2017
Azienda di Rilievo Nazionale ed Alta Specializzazione
2017
Policlinico Universitario di Catania
2008-2009
University of Messina
2003-2008
Modern monitoring techniques contribute to accurately describing the structural health conditions of historical buildings and optimizing plan maintenance as well restoring intervention. Particularly, dynamic testing gives knowledge about global behavior can be used calibrate numerical models predict response earthquake loading. In some circumstances, vibration-based also help in evaluating safety conditions. The present article proposes a discussion methodological multidisciplinary approach...
Abstract Thyroid carcinoma (TC) is the most common malignancy of endocrine organs. The cell subpopulation in lineage hierarchy that serves as origin for different TC histotypes unknown. Human embryonic stem cells (hESCs) with appropriate vitro stimulation undergo sequential differentiation into thyroid progenitor (TPCs-day 22), which maturate thyrocytes (day 30). Here, we create follicular cell-derived TCs all based on specific genomic alterations delivered by CRISPR-Cas9 hESC-derived TPCs....
Abstract The growth rate of a 4H‐SiC epitaxial layer has been increased by factor 19 (up to 112 μm h –1 ) with respect the standard process, introduction HCl in deposition chamber. layers grown addition characterized electrical, optical, and structural characterization methods. effects various parameters on process have described, an explanation this behavior terms diffusion coefficient surface, D s , ratio between characteristic times, τ :τ G provided. diodes, manufactured at 1600 °C,...
The use of stem cells, including mesenchymal cells (MSCs), for regenerative medicine is gaining interest the clinical benefits so far obtained in patients. This study investigates adipose autologous tissue combination with platelet-rich plasma (PRP) to improve outcome patients affected by systemic sclerosis (SSc). Adipose-derived (AD-MSCs) and PRPs were purified from healthy donors SSc multilineage differentiation potential AD-MSCs their genotypic–phenotypic features investigated. A cytokine...
Actinic keratosis (AK) is a common keratinocyte intra-epidermal neoplasia. To assess AK prevalence and potential risk factors in patients attending Italian general dermatology clinics. This retrospective study was conducted on clinical data from consecutive white outpatients aged ≥30 years, 24 clinics between December 2014 February 2015. (entire population) multivariate factor analysis (patients with current/previous complete data) are presented. 7,284 27.4% (95% CI: 26.4-28.4%); 34.3% men...
Abstract Background Hidradenitis suppurativa ( HS ) is a chronic, relapsing, inflammatory skin disease characterized by painful inflamed nodules, recurrent abscesses and fistulas located in apocrine gland–bearing body sites. The negative impact of on patient's quality life (QoL) has been reported to be greater than other dermatologic conditions as psoriasis atopic eczema, its improvement an important goal management. Nowadays, there are no specific validated QoL instruments available for...
Sexually transmitted infections (STIs) are a serious global health problem. In Italy, data describing the vulnerability to STIs of specific sexual minorities and influence sociodemographic behavioral determinants limited, as most not subject mandatory notification. This retrospective study describes profile main behaviors patients attending hospital in Palermo (Sicily, Italy) from January 2018 March 2019 predictors STI risk. Patients were divided subgroups: men-who-have-sex-with-men (MSM),...
Breast cancer (BC) is the second cause of cancer-related deceases in worldwide female population. Despite successful treatment advances, 25% BC develops resistance to current therapeutic regimens, thereby remaining a major hurdle for patient management. Current therapies, targeting molecular events underpinning adaptive resistance, still require effort improve treatment. Using sphere cells (BCSphCs) as model, here we showed that stem-like express high levels Myc, which requires presence...
The aim of this study is to analyse alterations the tongue and correlation between these lesions different types tumor.A total 258 cases (131 females, 127 males) neurofibromatosis type 1 were screened 1994 2004 in our Dermatology Department. All patients included have NF1, as defined by NIH Consensus Conference. Three neurofibromas with reported.Our showed nodular on tongue, related two plexiform neurofibroma one patient, respectively. Clinical hystopatological findings useful distinguishing...
Abstract Despite intense research and clinical efforts, patients affected by advanced colorectal cancer (CRC) have still a poor prognosis. The discovery of (CR) stem cell (CSC) as the compartment responsible for tumor initiation propagation may provide new opportunities development therapeutic strategies. Given reduced sensitivity CR-CSCs to chemotherapy ability bone morphogenetic proteins (BMP) promote colonic differentiation, we aimed investigate whether an enhanced variant BMP7 (BMP7v)...
The results of a new epitaxial process using an industrial 6x2” wafer reactor with the introduction HCl during growth have been reported. A complete reduction silicon nucleation in gas phase has observed even for high dilution parameters (Si/H2>0.05) and increase rate until about 20 µm/h measured. No difference terms defects, doping uniformity (average maximum variation 8%) thickness 1.2 %) respect to standard without HCl.
P63 is a transcription factor belonging to the family of p53, essential for development and differentiation epithelia. In recent years, it has become clear that altered expression different isoforms this gene can play an important role in carcinogenesis. The p63 encodes two main known as TA ΔN with functions. these sustaining tumor progression metastatic spreading however not entirely been clarified. Here we show breast cancer initiating cells express ΔNp63 isoform supports more mesenchymal...
Fabry disease (FD) [OMIM 301500] is an X-linked lysosomal storage disorder caused by a deficiency of the enzyme alpha-galactosidase A, resulting in progressive multisystem accumulation globotriaosylceramide (Gb3). Although introduction Enzyme Replacement Therapy (ERT) resulted variety clinical benefits, life-long intravenous (IV) treatment with ERT every other week schedule, may interfere daily life activities and impact on QoL. We report here multicentric, observational, longitudinal data...
Hidradenitis suppurativa (HS) is a disorder of the apocrine gland causing chronic, recurrent and painful inflammation. It disabilitating condition and, though many therapeutic options are available, response often ineffective in most cases patients can present recurrences with physical psychological sequelae. Recent data had shown increased interleukin (IL)-17 serum levels HS. Psoriasis chronic immune-mediated inflammatory new evidences have role Th17 cells its pathogenesis efficacy...
Psoriatic arthropathy is a progressive and debilitating disease involving reduction of functional activity the articulations with consequent deterioration patient's quality life. The entheses represent initial site articular inflammation enthesis Achilles tendon first to be affected. In some patients psoriasis, enthesitis may not diagnosed because it still asymptomatic.To evaluate whether ultrasonography allows early diagnosis in larger population identify significant alterations beyond...
Abstract Background The term “leishmaniasis” defines a group of vector‐borne diseases caused by species the genus Leishmania and characterized spectrum clinical manifestations. Parasite properties (infectivity, pathogenicity, virulence), host factors, responses regulate heterogeneous disease expression. Sicily is one major islands Mediterranean Basin considered to be hypo‐endemic area for cutaneous leishmaniasis. infantum most common on island. Methods Fifty patients (both sexes different...
Sunscreen protection in subjects with actinic keratosis (AK) is highly recommended to prevent clinical evolution of this situ skin cancer condition. Use topical anti-cyclooxygenase drugs such as diclofenac and piroxicam reduces the number lesions improves cancerization field. A film-forming medical device a cream formulation containing organic inorganic sun-filters (50+ SPF) 0.8% (ACTX) has shown pilot, single-center, open trial reduce AK improving field.We evaluated multicenter,...
4H-SiC epitaxial layers have been grown using trichlorosilane (TCS) as the silicon precursor source together with ethylene carbon source. A higher C/Si ratio is necessary compared silane/ethylene system. This has to be reduced especially at Si/H2 because step-bunching effect occurs. From comparison process that uses silane precursor, a 15% growth rate found TCS (trichlorosilane) same ratio. Furthermore, in process, presence of chlorine, reduces possibility droplet formation, allows use high...