A5008604622- Traditional Chinese Medicine Studies
- Complementary and Alternative Medicine Studies
- Blood groups and transfusion
- Neonatal Respiratory Health Research
- Orthopedic Infections and Treatments
- Extracellular vesicles in disease
- Renal and Vascular Pathologies
- Neonatal and fetal brain pathology
- Acupuncture Treatment Research Studies
- Nanoparticles: synthesis and applications
- Medicinal Plants and Bioactive Compounds
- Influenza Virus Research Studies
- Erythrocyte Function and Pathophysiology
- Viral Infections and Immunology Research
- Vagus Nerve Stimulation Research
- Plant-based Medicinal Research
- Nerve injury and regeneration
- Renal Transplantation Outcomes and Treatments
- Virology and Viral Diseases
- Animal Virus Infections Studies
- Immune Response and Inflammation
- Infant Nutrition and Health
- Organ Donation and Transplantation
- Vitamin C and Antioxidants Research
- Respiratory viral infections research
Medical University of Vienna
2020-2025
Institute of Pharmacology
2023
Max Perutz Labs
2021-2022
Nonpathogenic torque teno viruses (TTVs) are highly prevalent in transplant recipients and associated with immunosuppression. Studies kidney patients have proposed assessment of TTV load for risk stratification clinically overt graft rejection. The value quantification the context subclinical rejection has not been evaluated.In this prospective trial, 307 consecutive were subjected to per-protocol monitoring plasma TTV. was analyzed protocol biopsies (n = 82), scheduled 1 year...
Despite the paucity of evidence verifying its efficacy and safety, traditional Chinese medicine (TCM) is expanding in popularity political support. Decisions to include TCM diagnoses International Classification Diseases 11th Revision campaigns integrate into national healthcare systems have occurred while public perception usage TCM, especially Europe, remains undetermined. Accordingly, this study investigates TCM's popularity, perceived scientific support, as well relationship homeopathy...
The gut microbiota and the immune system are closely connected, influencing early-life brain development. Brain-derived neurotrophic factor (BDNF), crucial for neuronal development, has been demonstrated to be produced by certain cells. However, modulation of BDNF during bacterial antigen metabolite challenge remains elusive. We investigate effects bacterial-derived antigens metabolites on secretion in human PBMCs. Although levels were altered stimulation, a specific cellular origin within...
Abstract Background and objectives Viral respiratory infections significantly affect young children, particularly extremely premature infants, resulting in high hospitalization rates increased health‐care burdens. Nasal epithelial cells, the primary defense against infections, are vital for understanding nasal immune responses serve as a promising target uncovering underlying molecular cellular mechanisms. Methods Using trans‐well pseudostratified cell system, we examined age‐dependent...
Ascorbic acid (AA; or vitamin C) is an important physiological antioxidant and radical scavenger. Some mammalian species, including homo sapiens, have lost the ability to synthetize AA depend on its nutritional uptake. Erythrocytes from AA-auxotroph mammals express high amounts of glucose transporter GLUT1. This isoform enables rapid uptake as well dehydroascorbate (DHA), fully oxidized form AA. Here, we explored effects DHA redox metabolism human erythrocytes. enhanced plasma membrane...
Background. Pretransplant kidney graft biopsies have been suggested for organ quality assessment. Data on the association between donor proteinuria and of deceased donors are not available. Methods. In this prospective study, we analyzed 147 pretransplant from 88 adult procured transplanted consecutively at Medical University Vienna July 2017 May 2020. Lesions in each renal compartment were scored 0 to 5 with ascending score representing a 20% increase damage. A chronic lesions was...
Upon birth, a hitherto naïve immune system is confronted with plethora of microbial antigens due to intestinal bacterial colonization. To prevent excessive inflammation and disruption the epithelial barrier, physiological mechanisms must promote immune-anergy within neonatal gut. As high concentrations human lactoferrin (hLF), transferrin glycoprotein shown modulate macrophage function, are frequently encountered in colostrum, its direct interaction macrophages may satisfy this need. Thus,...
ABSTRACT Introduction Despite the paucity of evidence verifying its efficacy and safety, traditional Chinese medicine (TCM) is expanding in popularity political support. Decisions to include TCM diagnoses International Classification Diseases 11th Revision (ICD-11) by World Health Organization (WHO) campaigns integrate into national healthcare systems have occurred whilst public perception usage TCM, especially Europe, remains undetermined. Accordingly, this study investigates popularity,...