A5100349481- Catalytic C–H Functionalization Methods
- Chemical Synthesis and Reactions
- Asymmetric Hydrogenation and Catalysis
- Catalytic Cross-Coupling Reactions
- Advanced Surface Polishing Techniques
- Carbohydrate Chemistry and Synthesis
- Platelet Disorders and Treatments
- Advanced oxidation water treatment
- Cyclopropane Reaction Mechanisms
- Antiplatelet Therapy and Cardiovascular Diseases
- Oxidative Organic Chemistry Reactions
- Chemical Synthesis and Analysis
- Diamond and Carbon-based Materials Research
- Advanced Combustion Engine Technologies
- Metal and Thin Film Mechanics
- Advanced Photocatalysis Techniques
- Sulfur-Based Synthesis Techniques
- Multicomponent Synthesis of Heterocycles
- Vanadium and Halogenation Chemistry
- Ionic liquids properties and applications
- Autoimmune and Inflammatory Disorders Research
- Vehicle emissions and performance
- Synthesis and Catalytic Reactions
- Environmental remediation with nanomaterials
- Chemistry and Chemical Engineering
Cummins (United Kingdom)
2025
Virginia Commonwealth University
2018-2024
Nanjing University of Information Science and Technology
2024
Tianjin University
2011-2023
Affiliated Hospital of Jining Medical University
2023
Jiamusi University
2023
Tianjin Academy of Environmental Sciences
2022
Tianjin Institute of Pharmaceutical Research (China)
2018-2022
Nanjing Tech University
2022
Zhejiang University of Technology
2020
Pd-catalyzed decarboxylative cross-couplings of 2-(2-azaaryl)acetates with aryl halides and triflates have been discovered. This reaction is potentially useful for the synthesis some functionalized pyridines, quinolines, pyrazines, benzoxazoles, benzothiazoles. Theoretical analysis shows that nitrogen atom at 2-position heteroaromatics directly coordinates to Pd(II) in decarboxylation transition state.
A novel alkyne-activation-based glycosylation protocol using o-(p-methoxyphenylethynyl)phenyl (MPEP) glycoside was established. The glycosyl MPEP donors were shelf-stable and could be prepared efficiently via Sonogashira reaction from the corresponding o-iodophenyl (IP) glycosides. outstanding stability of IP glycosides as well their efficient transformations to dramatically facilitates syntheses acceptors. Furthermore, they make applicable latent-active oligosaccharide glycoconjugate...
A dehydrogenative [3 + 2] annulation reaction of aniline derivatives and alkenes has been developed via the ruthenium-electron catalytic systems for synthesis versatile indolines. Electricity is used as a sustainable oxidant to regenerate active Ru(II) catalyst promote H2 evolution. This protocol ecofriendly easy handle it uses simple undivided cell in mild conditions without employment metal oxidants.
A convergent route to a variety of C-1-disaccharide glycals based on the olefin metathesis reaction enol ethers and alkenes is described. The DCC-mediated coupling pentose enitols (1a−c) with number C-5- C-6-monosaccharide carboxylic acids (2a−e) gave corresponding esters 3a−l in good yield. Methylenation these compounds was followed by ring-closing metathesis, mediated Schrock molybdenum catalyst 8 warm toluene, provide target C-disaccharide 5a−l. formed ether double bond 5a then...
Carbon−oxygen bond-forming reductive elimination from transient Pd(IV) aryl/acetate complexes was recently implicated as the product release step in Pd(II)-catalyzed arene oxygenation reactions. The mechanistic details of C−O bond formation these intermediates remain elusive and, therefore, are subjected to a systematic theoretical investigation present study. Three proposed mechanisms examined including (A) pre-equilibrium dissociation benzoate ligand followed by resulting five-coordinate...
Abstract Immune thrombocytopenia (ITP) is an acquired autoimmune disease characterized by immune mediated decrease in platelet number. Disturbance of CD4 + T‐cell homeostasis with simultaneous CD25 Foxp3 regulatory T cells (Tregs) as well unrestricted proliferation and activation peripheral effector underpin the pathophysiology ITP. Indirubin active ingredient a traditional Chinese herb called Indigofera tinctoria L. which clinically used for treatment ITP patients. Whether indirubin targets...
<div class="section abstract"><div class="htmlview paragraph">This work is part of a production-intent program at Cummins to develop 6.7L direct injection (DI), lean burn H2 spark ignition (SI) engine for medium- and heavy-duty commercial vehicles that are intended be compliant with global VII criteria pollutants emissions standards. The features low-pressure DI fuel system, tumble-based combustion system pent-roof chamber, two-stage boosting without EGR, dual overhead cams...
The selectivity is meta! Recent developments on transition-metal catalyzed meta-selective CH functionalization are highlighted (see scheme; EDG=electron-donating group, EWG=electron-withdrawing group). method complementary to traditional methodologies and might provide numerous opportunities access previously difficult organic products. Possible mechanisms discussed.
The mechanism of a recently discovered intramolecular Heck-type coupling oximes with aryl halides (Angew. Chem. Int. Ed. 2007, 46, 6325) was systematically studied by using density functional methods enhanced polarized continuum solvation model. overall catalytic cycle the reaction found to consist four steps: oxidative addition, migratory insertion, beta-H elimination, and catalyst regeneration, whereas an alternative base-promoted C-H activation pathway determined be less favorable....
A quantitative one-pot synthesis method for industrial azo pigments with recyclable granular PTFE, wastewater and excess HCl is reported.
These reactions offered advantages including green oxidation by O<sub>2</sub> in air, simple workups and wide scope of substrates.
Purpose This paper aims to reveal the mechanism for improving ductile machinability of 3C-silicon carbide (SiC) and associated cutting in stress-assisted nanometric cutting. Design/methodology/approach Molecular dynamics simulation nano-cutting 3C-SiC is carried out this paper. The following two scenarios are considered: normal 3C-SiC; comparison. Chip formation, phase transformation, dislocation activities shear strain during analyzed. Findings Negative rake angle can produce necessary...