A5100333643- Orthopedic Surgery and Rehabilitation
- Birth, Development, and Health
- Bladder and Urothelial Cancer Treatments
- Vitamin D Research Studies
- Pancreatic function and diabetes
- Gestational Diabetes Research and Management
- Orthopaedic implants and arthroplasty
- Tissue Engineering and Regenerative Medicine
- Bone fractures and treatments
- Pancreatic and Hepatic Oncology Research
- Elbow and Forearm Trauma Treatment
- Esophageal and GI Pathology
- Shoulder Injury and Treatment
- Diabetes and associated disorders
- Maternal Mental Health During Pregnancy and Postpartum
- Nutrition and Health in Aging
- Magnetic properties of thin films
- Orthopedic Infections and Treatments
- Abdominal Trauma and Injuries
- Pregnancy and preeclampsia studies
- Esophageal Cancer Research and Treatment
- Ferroelectric and Negative Capacitance Devices
- Chronic Disease Management Strategies
- Congenital Diaphragmatic Hernia Studies
- Helicobacter pylori-related gastroenterology studies
Second Affiliated Hospital of Zhejiang University
2022-2025
Acumen (United States)
2025
Gannan Medical University
2025
Soochow University
2014-2025
Second Affiliated Hospital of Soochow University
2022-2025
Tianjin Medical University
2009-2025
University of Pittsburgh
2024-2025
Shanghai Children's Medical Center
2022-2024
Shanghai Jiao Tong University
2022-2024
Shanghai Ninth People's Hospital
2024
The current-induced perpendicular magnetic anisotropy tunnel junctions (p-MTJs) offer a number of advantages, such as high density and speed. As p-MTJs downscale to ~40 nm, further performance enhancements can be realized thanks spin-torque efficiency, i.e., lower critical current higher thermal stability. In this paper, we investigate the origin efficiency give phenomenological theory describe reduction due subvolume activation. Based on various physical theories structural parameters,...
The miniaturization of integrated circuits based on complementary metal oxide semiconductor (CMOS) technology meets a significant slowdown in this decade due to several technological and scientific difficulties. Spintronic devices such as magnetic tunnel junction (MTJ) nanopillar become one the most promising candidates for next generation memory logic chips thanks their non-volatility, infinite endurance, high density. A processor spintronic is then expected overcome issue increasing...
Alcoholic liver disease (ALD) is a major worldwide chronic accompanied by hepatic inflammation, gut leakiness, and abnormal oxidative stress. Our previous study demonstrated substantial hepatoprotective activity of the active Poria cocos polysaccharide (PCP-1C). The present explored whether PCP-1C protects against ALD among results showed that significantly improved alcohol-induced injury decreasing serum biochemical parameters, alleviating steatosis, reducing lipid accumulation caused ALD....
Objectives We aimed to explore the efficacy and safety of tailored therapy guided by genotypic resistance in first‐line treatment Helicobacter pylori ( H. ) infection treatment‐naive patients. Methods Gastric mucosal specimens were taken during gastroscopy, main mutations clarithromycin‐ levofloxacin‐resistant genes detected polymerase chain reaction (PCR). Sensitive antibiotics selected individually for treating with bismuth‐containing quadruple (BQT) consisting esomeprazole 20 mg twice...
COVID-19 has been associated with an increased risk for thromboembolic events, including ischemic stroke, venous thromboembolism, and myocardial infarction.Studies have reported lower rates of COVID-19-related events among persons who received the vaccine compared did not, but rigorous estimates effectiveness (VE) in preventing are lacking.This analysis estimated incremental benefit receipt a bivalent mRNA after receiving original monovalent vaccine.To estimate VE dose doses only, two...
With the continuous shrinking of technology node, conventional CMOS logic circuits suffer from high power issues due to both increasing leakage current and long traffic delay. Hybrid non-volatile (NV) logic-in-memory architecture, where emerging NV memories are distributed over a logic-circuit plane, has been widely investigated overcome these limitations. Magnetic tunnel junction (MTJ) is considered as one most promising candidates thanks its non-volatility, fast access speed, infinite...
Abstract Background Postpartum depression (PPD) is a common mental disease happens in perinatal period. Ketamine as an anesthesia and analgesia drug has been used for long time. In recent years, ketamine proved to have antidepression effect with single administration. We hypothesized that intraoperative can reduce postpartum depressive symptoms after cesarean delivery. Methods randomized, double‐blind, placebo‐controlled study trail, healthy women scheduled delivery were randomly assigned...
No AccessJournal of UrologyAdult Urology1 Oct 2021Urinary Molecular Pathology for Patients with Newly Diagnosed Urothelial Bladder CancerThis article is commented on by the following:Editorial CommentEditorial Comment Ruiyun Zhang, Jingyu Zang, Feng Xie, Yue Yiqiu Wang, Ying Jing, Yi Zhaoxiong Chen, Akezhouli Shahatiaili, Mei-Chun Cai, Zhixin Zhao, Pan Du, Shidong Jia, Guanglei Zhuang, and Haige Chen ZhangRuiyun Zhang Department Urology, Ren Ji Hospital, School Medicine, Shanghai Jiao Tong...
Abstract Glucagon has emerged as a key regulator of extracellular amino acid (AA) homeostasis. Insufficient glucagon signaling results in hyperaminoacidemia, which drives adaptive proliferation glucagon-producing α cells. Aside from mammalian target rapamycin complex 1 (mTORC1), the role other AA sensors cell not been described. Here, using both genders mouse islets and receptor ( gcgr )-deficient zebrafish Danio rerio ), we show requires activation signal-regulated protein kinase (ERK1/2)...
The prevalence of high-risk pregnancy increased after the implementation two-child policy in China, but impact this change on burden and profile multiple factors (MHFP) has been insufficiently explored. We hypothesised that MHFP might have changed was implemented aimed to estimate prevalence, intercorrelation, outcomes before its introduction.
To explore the mechanical stability of unstable pertrochanteric fractures with proximal femoral nail anti-rotation (PFNA-Ⅱ) fixation under different anteromedial cortical support reduction patterns.A 65-year-old healthy male volunteer no history hip or systemic disease was recruited. High-resolution computed tomography images a slice thickness 0.67 mm his right femur were obtained. These used to establish three-dimensional (3D) models. The lesser trochanter and lateral wall cut off create an...
Helicobacter pylori colonizes over 50% of people worldwide. Biofilm formation through penetrating gastric mucus and resistance acquired by H. markedly reduces the efficacy traditional antibiotics. The present triple therapy bismuth-based quadruple inevitably causes intestinal flora disturbance fails to address excessive pylori-triggered inflammatory response. Herein, a mucus-permeable therapeutic platform (Cu-MOF@NF) that consists copper-bearing metal-organic framework (Cu-MOF) loaded with...
Abstract Background Persons with end stage renal disease (ESRD) on maintenance dialysis are at high risk for severe COVID-19 disease. On September 12, 2023, updated 2023-2024 vaccination was recommended in the United States all persons aged ≥6 months. Due to innate immune dysfunction and prevalence of additional underlying conditions, including immunocompromising conditions (ICs), among individuals ESRD, there is concern about reduced vaccine effectiveness (VE). Understanding VE doses ESRD...
Introduction: The gut-brain axis is pivotal in recovery after stroke, with the gut microbiome playing a significant role neurological outcomes. Akkermansia muciniphila (AKK), beneficial bacterium, has shown promise metabolic conditions. We hypothesize that AKK and its exosomes (AKK-Exo) can enhance stroke by modulating interactions. Methods: Human study: fecal samples from 88 ischemic (IS) patients 23 healthy elderly were analyzed using 16S rDNA sequencing. Animal 6-8 months old male mice...
Background: Obstructive sleep apnea syndrome (OSAS) is closely related to multiple biological mechanisms, particularly its impact on the cardiovascular system. Long term OSAS may exacerbate issues such as hypertension, disease, and aortic disease. The aim of this study explore effects continuous positive airway pressure (CPAP) therapy mechanisms patients, with a focus analyzing responses blood pressure, respiration, changes. Method: This retrospectively analyzed case 75 year old male patient...
Abstract Background: Bladder cancer, the sixth most common cancer worldwide, has a high recurrence rate, necessitating frequent and reliable disease monitoring. Current methods, such as cystoscopy, are invasive can hinder patient compliance. However, detecting therapy response progression on molecular level still remains challenging. Urinary tumor DNA (utDNA) analysis offers promising, non-invasive, highly sensitive diagnostic tool for bladder diagnosis By utDNA methylation profiles, this...
Abstract A sedentary lifestyle significantly increases the risk of cancer. In contrast, exercise has been associated with enhanced antitumor immunity and improved immune checkpoint inhibitor (ICI) efficacy in cancers like melanoma. However, mechanisms through which mediates this effect remain obscure. Here, we demonstrate for first time that exercise-induced changes to microbiota are a critical mechanism by enhances previously unrecognized pathway. First, show exercise-mediated tumor...