A5013654650- Congenital Heart Disease Studies
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiac Arrest and Resuscitation
- Cardiac Valve Diseases and Treatments
- Hemodynamic Monitoring and Therapy
- Advanced MRI Techniques and Applications
- Cardiovascular Issues in Pregnancy
- Aortic Disease and Treatment Approaches
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Syncope and Autonomic Disorders
- ECG Monitoring and Analysis
- Pulmonary Hypertension Research and Treatments
- Coronary Artery Anomalies
- Chemotherapy-induced cardiotoxicity and mitigation
- Sepsis Diagnosis and Treatment
- Anesthesia and Sedative Agents
- Airway Management and Intubation Techniques
- Renal function and acid-base balance
- Healthcare Technology and Patient Monitoring
- Artificial Intelligence in Healthcare
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac electrophysiology and arrhythmias
- Down syndrome and intellectual disability research
- Breastfeeding Practices and Influences
Children's Hospital of Philadelphia
2021-2025
University of Pennsylvania
2022-2025
Philadelphia University
2025
University of Arkansas for Medical Sciences
2015-2018
Johns Hopkins University
2018
Johns Hopkins Medicine
2018
Arkansas Children's Hospital
2016
Children's Hospital & Medical Center
2011-2013
University of Nebraska Medical Center
2012-2013
University of Nebraska–Lincoln
2013
Dobutamine stress cardiovascular magnetic resonance (DS-CMR) is an established tool to assess hibernating myocardium and ischemia. Analysis typically based on visual assessment with considerable operator dependency. CMR myocardial feature tracking (CMR-FT) a recently introduced technique for tissue voxel motion standard steady-state free precession (SSFP) images derive circumferential radial mechanics. We sought determine the feasibility reproducibility of CMR-FT quantitative wall during...
We investigated intermodality agreements of strains from two‐dimensional echocardiography (2 DE ) and cardiac magnetic resonance ( CMR feature tracking FT in the assessment right RV left ventricular LV mechanics tetralogy Fallot TOF ). Patients were prospectively studied with 2 performed contiguously. computed separately using ‐ . Segmental global longitudinal GLS for measured four‐chamber views; radial (global strain [ GRS ]) circumferential GCS short‐axis views. Intermodality interobserver...
Doxorubicin is associated with a cumulative dose-dependent nonischemic cardiomyopathy. Cardiac magnetic resonance imaging (cMRI) able to examine both structural and functional components of the myocardium. Our aim was assess myocardial changes in non-Hodgkin lymphoma patients undergoing doxorubicin-based chemotherapy using cMRI.cMRI examination performed before 3 months after chemotherapy. Experienced investigators interpreted each cMRI, were blinded all data. Left ventricular ejection...
New Findings What is the central question of this study? How do left ventricular volumes measured in a large animal using admittance catheterization compare with those three‐dimensional echocardiography or traditional conductance? main finding and its importance? Admittance computed were validated baseline conditions during inotropic stimulation dobutamine. These results serve as foundation for use large‐animal experimental models cardiovascular disease. The Wei's equation new technique...
Retained intravascular foreign body is a well-known complication of central venous access placement in children as well adults. Most these bodies are radio-opaque and hence removed under fluoroscopy guidance. In our case, we describe the removal an intracardiac radiolucent infant utilizing combination technique - transesophageal echocardiogram fluoroscopy.
Objective: To evaluate the outcomes associated with use of inhaled nitric oxide during extracorporeal membrane oxygenation. Design: Post hoc analysis data from an existing administrative national database, Pediatric Health Information system (2004–2014). Multivariable logistic regression models were fitted to study effect oxygenation on outcomes. Setting: Forty-two children’s hospitals across United States. Patients: Patients in age group 1 day through 18 years admitted ICU who received...
The aim of this study was to investigate the left ventricular (LV) myocardial contractility index-Emax using transesophageal real time three-dimensional echocardiography (RT3DE) combined with catheterization.Transesophageal RT3DE (single beat, X7-2 × matrix, iE33, Philips) used obtain LV volumes in pigs. Volumes were integrated pressures from conductance catheterization (CC) create pressure-volume relations. At same time, CC for measuring conventional relations that served as reference....
With the increasing prevalence of Down Syndrome, it is unknown if children with Syndrome are associated increased incidence cardiac arrest and poor outcomes after arrest. The objective this study was to evaluate epidemiology mortality among critically ill without Syndrome.Patients ≤18 years admitted at a Pediatric Health Information Systems (PHIS) participating Intensive Care Unit were included (2004-2014). Multivariable logistic regression models fitted association adjusting for patient...
Background: Infants are at risk of cerebral hypoperfusion from low blood pressure during anesthesia. We conducted a retrospective observational study to determine the patient and perioperative factors associated with systolic (SBP) in healthy infants. Methods: obtained data 266 infants aged 0–6 months who underwent inguinal hernia repair between January 2015 March 2019 our institution. SBP was analyzed two phases: preparation phase (20 min before procedure start until incision) surgical (15...
We sought to determine the feasibility and reproducibility of cardiac magnetic resonance (CMR) myocardial feature tracking (FT) for quantitative wall motion assessment during intermediate dose dobutamine stress (DSMR) imaging.
Prior research on red blood cell (RBC) storage duration and clinical outcomes in paediatric cardiac surgery has shown conflicting results. The purpose of this study was to evaluate whether stored for a longer is harmful these patients.We performed retrospective cohort patients undergoing at our institution between January 2011 June 2015. Patients were stratified based they transfused RBCs ≤15 days (fresher blood) or >15 (older blood). primary outcome composite morbidity, with prolonged...