Andrei C. Spósito
A5086183706- Lipoproteins and Cardiovascular Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Function and Risk Factors
- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Disease Prevention
- Cardiac Imaging and Diagnostics
- Diabetes Treatment and Management
- Cardiovascular Disease and Adiposity
- Acute Myocardial Infarction Research
- Diabetes Management and Research
- Heart Rate Variability and Autonomic Control
- Adipokines, Inflammation, and Metabolic Diseases
- Health Systems, Economic Evaluations, Quality of Life
- COVID-19 Clinical Research Studies
- Cancer, Lipids, and Metabolism
- Metabolism, Diabetes, and Cancer
- Atherosclerosis and Cardiovascular Diseases
- Public Health in Brazil
- Heart Failure Treatment and Management
- Liver Disease Diagnosis and Treatment
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Nutritional Studies and Diet
- Coronary Interventions and Diagnostics
- Cardiac Ischemia and Reperfusion
- Cholesterol and Lipid Metabolism
Universidade Estadual de Campinas (UNICAMP)
2016-2025
Hospital de Clínicas da Unicamp
2014-2024
Institute for Atherosclerosis Research
2024
Massachusetts General Hospital
2019-2023
GTx (United States)
2023
Creighton University
2023
Sociedade Brasileira de Cardiologia
2002-2022
Universidade de Brasília
2007-2021
Hospital de Base
2011-2021
Impact
2021
Content 1. Definition, Epidemiology, and Primary Prevention 528 1.1 Definition of Hypertension […] Brazilian Guidelines – 2020
Brazil currently has one of the fastest-growing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemics in world. Because limited available data, assessments impact nonpharmaceutical interventions (NPIs) on this virus spread remain challenging. Using a mobility-driven transmission model, we show that NPIs reduced reproduction number from >3 to 1 1.6 São Paulo and Rio de Janeiro. Sequencing 427 new genomes analysis geographically representative genomic dataset identified >100...
O Departamento de Aterosclerose da Sociedade Brasileira Cardiologia (SBC), acompanhando o amplo cenário publicações científicas sobre tratamento das dislipidemias e prevenção aterosclerose, bem como a importância seu impacto risco cardiovascular, reconhecendo necessidade atualização sua última diretriz, publicada em 2013, conformidade com as recomendações SBC, reuniu um comitê especialistas, clínica do laboratório clínico, partir janeiro 2016, para elaboração deste documento, que ora...
Nota: o conjunto de recomendações emitidas nesta Diretriz, forma geral, reflete as evidências
Introducao A doenca cardiovascular (DCV) e a principal causa de morte no Brasil mundo, determinando aumento da morbidade incapacidade ajustadas pelos anos vida. Embora as taxas mortalidade disability-adjusted life year (DALY) padronizadas por idade estejam diminuindo Brasil, possivelmente como resultado politicas saude bem-sucedidas, o numero total destas esta aumentando principalmente devido ao envelhecimento adoecimento populacao. presenca dos fatores risco classicos (hipertensao,...
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the agent of a major global outbreak tract disease known as Coronavirus Disease 2019 (COVID-19). SARS-CoV-2 infects mainly lungs and may cause several immune-related complications, such lymphocytopenia cytokine storm, which are associated with severity predict mortality. mechanism by infection result in immune system dysfunction still not fully understood. Here, we show that human CD4+ T helper cells, but CD8+ present blood...
The effects of loading doses statins on clinical outcomes in patients with acute coronary syndrome (ACS) and planned invasive management remain uncertain.To determine if periprocedural atorvastatin decrease 30-day major adverse cardiovascular events (MACE) ACS management.Multicenter, double-blind, placebo-controlled, randomized trial conducted at 53 sites Brazil among 4191 evaluated angiography to proceed a percutaneous intervention (PCI) anatomically feasible. Enrollment occurred between...
COVID-19 can result in severe lung injury. It remained to be determined why diabetic individuals with uncontrolled glucose levels are more prone develop the form of COVID-19. The molecular mechanism underlying SARS-CoV-2 infection and what determines onset cytokine storm found patients unknown. Monocytes/macrophages most enriched immune cell types lungs appear have a central role pathogenicity disease. These cells adapt their metabolism upon become highly glycolytic, which facilitates...
Abstract Background The glucose-lowering independent effect of sodium glucose cotransporter-2 inhibitors (SGLT2i) on arterial wall function has not yet been clarified. This study aims to assess whether SGLT2i treatment can attenuate endothelial dysfunction related type 2 diabetes mellitus (T2D) compared with equivalent therapy. Methods In a prospective, open-label, single-center, randomized clinical trial, 98 patients T2DM and carotid intima-media thickness above the 75th percentile were 1:1...
Summary Part I - Diagnosis and risk stratification page 1 1. Introduction 2. 12.a. of subclinical coronary artery disease (CAD) 2.a.1. in symptomatic patients 12.b. manifest CAD 2 2.b.1. History, physical examination, differential diagnosis