A5101478852- Inflammatory Biomarkers in Disease Prognosis
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer, Lipids, and Metabolism
- Liver Disease Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Cancer-related Molecular Pathways
- Genetic and Kidney Cyst Diseases
- Ferroptosis and cancer prognosis
- Radiomics and Machine Learning in Medical Imaging
- Liver Disease and Transplantation
- Microtubule and mitosis dynamics
- Cancer Genomics and Diagnostics
- Genetic factors in colorectal cancer
- Endoplasmic Reticulum Stress and Disease
- Hepatitis B Virus Studies
- Alcohol Consumption and Health Effects
- Digestive system and related health
- Organ Transplantation Techniques and Outcomes
West China Hospital of Sichuan University
1969-2025
Sichuan University
1969-2025
The First People's Hospital of Wenling
2018
Harbin Medical University
2016
Second Affiliated Hospital of Harbin Medical University
2016
4104 Background: The combination of atezolizumab and bevacizumab is the standard treatment for advanced hepatocellular carcinoma approved in China many other countries. However, objective response rate this was around 30%. Consequently, identifying individuals with potential to respond favorably prior initiating therapy remains a pressing challenge. Methods: This multi-center retrospective study included patients who received plus as first-line between December 2020 February 2024. training...
ABSTRACT Background Although cryosurgery has been proved to be an effective treatment extend the survival time of unresectable liver cancer patients and improve their quality life, few surgeons actually treat pancreatic with this method because its safety risks. This study aims evaluate efficacy cryosurgical ablation in for cancer. Methods A retrospective was conducted on 142 who underwent palliative bypass cryoablation (PBC group: 68) or without (PB 74) from 1995 2002. The morbidity 5 year...
Abstract For many malignancies, inflammation-based scores correlate with survival. The neutrophil-to-lymphocyte ratio (NLR) and prognostic nutritional index (PNI) are immunonutritional indices associated postoperative outcomes in patients hepatocellular carcinoma (HCC). We evaluated whether a combined preoperative NLR PNI score was prognostically superior to either alone 793 unresectable HCC after transarterial chemoembolization. Patient demographic, clinical, pathological data were also...
There is little information regarding the predictive ability of albumin-bilirubin grades (ALBI) plus platelet-to-lymphocyte ratio (PLR) in patients with hepatocellular carcinoma (HCC) following liver resection. In this study, we aimed to evaluate prognostic power ALBI-PLR score hepatitis B virus-related (HBV-related) HCC within Barcelona Clinic Liver Cancer (BCLC) stage A after Around 475 were included study. Patients preoperative ALBI 1, 2, or 3 allocated a 0, respectively. PLR >150 ≤150 0...
There is currently limited information regarding the prognostic ability of dNLR-PNI (the combination derived neutrophil-to-lymphocyte ratio [dNLR] and nutritional index [PNI]) for hepatocellular carcinoma (HCC). This study aimed to assess predictive in patients with intermediate-to-advanced HCC after transarterial chemoembolization (TACE). A total 761 were enrolled study. The was retrospectively calculated these patients, as follows: both an elevated dNLR a decreased PNI, determined using...
Background: The prognostic value of expression the IQ motif containing GTPase activating protein 1 (IQGAP1) in hepatocellular carcinoma (HCC) following liver resection and its potential mechanism were unclear. In this study, we attempted to clarify them.
Platelet, neutrophil, and lymphocyte ratio (PNLR) has its own unique role in influencing postoperative recurrence for patients with hepatocellular carcinoma (HCC). Surgical stress can change systemic inflammatory response of patients. Thus the aim this study was to identify prognostic value changes platelet times neutrophil hepatitis B related HCC within Barcelona clinical liver cancer (BCLC) stage A. Data BCLC A were reviewed. Pre-, intra- variables retrospectively statistically analyzed....
To compare the outcomes of living donor liver transplantation (LDLT) versus deceased (DDLT) for patients with hepatocellular carcinoma (HCC) in different selection criteria.Data HCC who underwent between 2005 and 2013 at our center were reviewed. Clinical data LDLT recipients DDLT compared. The postoperative recurrence-free survival (RFS) rate overall (OS) after compared Milan recipients, University California, San Francisco (UCSF) up-to-seven Hangzhou Chengdu recipients.Data 255...
Inflammation-based markers are considered prognostic indicators for patients with hepatocellular carcinoma (HCC) after liver resection. However, there is little information concerning whether they useful HCC clinically significant portal hypertension (CSPH). In this study, 1452 were enrolled. Independent risk factors recurrence-free survival (RFS) and overall (OS) analyzed without CSPH. For CSPH, multivariate analysis suggested that microvascular invasion (MVI), neutrophil-to-lymphocyte...
Abstract Background An elevated preoperative aspartate aminotransferase‐to‐lymphocyte ratio index (ALRI) may predict poor survival in various cancers. However, the prognostic value of patients with hepatocellular carcinoma (HCC) remains to be determined. Materials and methods A retrospective cohort study was conducted among 983 HCC our hospital from February 2007 March 2016. propensity‐score matching (PSM) performed correct selection bias confounding factors. The risk death recurrence...
Pancreatic serous cystic neoplasm (SCN) is a benign tumor of the pancreas, about two-thirds situated in tail pancreas. The small sized ones usually require only routine follow-ups, and advised for surgical treatment when clinical symptoms, mass growth are occurring rapidly, traditional splenectomy. Here, we have finished laparoscopy resection spleen-preserving pancreatic body. A 46-year-old female presents follow-up after physical examination found body pancreas two years ago. After had...
Background: The prognostic value of expression the IQ motif containing GTPase activating protein 1 (IQGAP1) in hepatocellular carcinoma (HCC) following liver resection and its potential mechanism were unclear. In this study, we attempted to clarify them. Methods: IQGAP1 HCC adjacent samples was assessed by immunohistochemistry staining, correlations with postoperative recurrence mortality also analyzed. Epithelial mesenchymal markers invasive migration ability cells examined cell lines...
Purpose Both the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte (PLR) reflect systematic inflammatory status. These values can be conveniently obtained from routine blood tests; however, their combined usefulness has not been extensively studied in patients with hepatocellular carcinoma (HCC). This study aimed to investigate prognostic value of NLR–PLR intermediate-to-advanced HCC who underwent transarterial chemoembolization (TACE).
Background: Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in China. Most HCC patients have complications chronic liver disease and need overall consideration whole-course management, including diagnosis, treatment, follow-up. To develop a reasonable, long-term, complete management plan, multiple factors to be considered, patient’s general condition, basic diseases, tumor stage, biological characteristics, treatment requirements, economic cost. Summary: better...
Pancreatic serous cystic neoplasm (SCN) is a benign tumor of the pancreas, about two-thirds situated in tail pancreas.The small sized ones usually require only routine follow-ups, and advised for surgical treatment when clinical symptoms, mass growth are occurring rapidly, traditional splenectomy.Here, we have finished laparoscopy resection spleen-preserving pancreatic body.A 46-year-old female presents follow-up after physical examination found body pancreas two years ago.After had become...
The traditional distal pancreatosplenectomy (DPS) has been the standard surgical procedure for treatment of resectable pancreatic carcinoma body and tail. With development medical technology, however, results including rate R0 resection, number lymph nodes dissected postoperative 5-year survival were not significantly improved after DPS. According to anatomy phylembryogenesis, combined with renewed tumor concept, radical antegrade modular (RAMPS) was put forward continuous exploration...
Background Elevated plasma fibrinogen (Fib) levels and a high preoperative neutrophil–lymphocyte ratio (NLR) are known to be associated with poor outcomes in hepatocellular carcinoma (HCC) patients. Herein, we investigated the prognostic value of combined NLR–Fib grade patients unresectable HCC.
Objective To establish a clinical scoring system for the prognosis of patients with single large hepatocellular carcinoma (HCC) after hepatectomy. Methods 268 HCC who underwent hepatectomy in West China Hospital Sichuan University from January 2009 to December 2013 were included this prospective study. There 227 males and 41 females, which 198 cases aged ≤60 years old, 70 aged>60 old. The informed consents all obtained local ethical committee approval was received. patients' survival...