A5100760880- MicroRNA in disease regulation
- Cancer Immunotherapy and Biomarkers
- Peroxisome Proliferator-Activated Receptors
- Cancer, Lipids, and Metabolism
- Lung Cancer Diagnosis and Treatment
- Circular RNAs in diseases
- Cellular Mechanics and Interactions
- Reproductive System and Pregnancy
- Inflammatory mediators and NSAID effects
- Extracellular vesicles in disease
- Lung Cancer Treatments and Mutations
- Muscle Physiology and Disorders
- Silk-based biomaterials and applications
- Cancer Cells and Metastasis
- Immune cells in cancer
- Cancer, Hypoxia, and Metabolism
- COVID-19 Impact on Reproduction
Qilu Hospital of Shandong University
2020
Zhengzhou University
2020
Nanfang Hospital
2020
Beijing Anzhen Hospital
2018
Capital Medical University
2018
Jinzhou Medical University
2017
First Affiliated Hospital of Zhengzhou University
2016
Although substantial studies on peroxisome proliferator-activated receptor g (PPARg) have focused the mechanisms by which PPARg regulates glucose and lipid metabolism, recent reports suggested that shows tumorigenic or antitumorigenic effects. The roles of activation in esophageal cancer remain unclarified. EC109 TE10 cells were treated with 0, 10, 20 40 mM agonist rosiglitazone (RGZ) for 24, 48, 72 h, cell viability apoptosis detected using methyl thiazolyl tetrazolium (MTT) assay Flow...
Abstract It is well known that the acquisition of chemoresistance a major obstacle for effective treatment human cancers. reported microRNAs (miRNAs) are implicated in chemotherapy resistance various malignancies. miR‐10b was previously proved as an oncogene multiple malignancies, including esophageal cancer. However, its biological significance regulating cisplatin (DDP) cancer still elusive. Here, we observed expression upregulated and peroxisome proliferator‐activated receptor‐γ (PPARγ)...
Circular RNAs (circRNAs) may serve as biomarkers for a potentially non-invasive diagnosis of cancer. To understand their diagnostic performance, systematic meta-analysis the published literature was conducted to review efficiency circRNAs in patients with Eligible studies up November 30, 2017, on PubMed and EMBASE, were selected meta-analysis. All carefully independently reviewed by two researchers based titles abstracts, following which full texts perused potential eligibility. statistical...
The cofilin 2 (CFL2) and myosin heavy chain (MyHC) genes play a key role in muscle development myofibrillar formation. aim of the present study was to investigate effect CFL2 on involved fiber formation mechanisms underlying this process. Undifferentiated differentiated C2C12 cells (UDT DT, respectively) were transfected with small interfering RNA (siRNA). mRNA protein levels assessed using reverse transcription polymerase reaction (RT-PCR) western blotting, respectively. MyHC gene...
L1 cell adhesion molecule (L1CAM) exhibits an oncogenic function in tumor. However, the link between L1CAM and tumor microenvironment is still obscure esophageal squamous carcinoma (ESCC) patients. In this study, we investigated how expression by ESCC affects characteristics of cells microenvironment. Here, found that significantly elevated tissues correlated with worse prognosis.Ablation inhibited growth migration, whereas increased apoptosis. microenvironment, was regulatory T (Tregs)...
Exosomes are a class of membranous vesicles, which approximately 50 to 100 nm in diameter; they released into the extracellular matrix from various cells.[1] rich proteins, lipids, and nucleic acids. They have been reported be involved physiological processes important tools for intercellular material information communication.[2,3] Increasing evidence has indicated that exosomes can extracted human saliva, urine, blood, other body fluids.[4] However, whether exist nipple discharge remains...