A5100409430- Pharmaceutical industry and healthcare
- Pharmaceutical Economics and Policy
- Pharmacological Effects of Natural Compounds
- Consumer Market Behavior and Pricing
- Computational Drug Discovery Methods
- Pharmacogenetics and Drug Metabolism
- Health Systems, Economic Evaluations, Quality of Life
- Economic and Environmental Valuation
- Drug-Induced Hepatotoxicity and Protection
- Plant-based Medicinal Research
- Pharmacological Receptor Mechanisms and Effects
- Analytical Chemistry and Chromatography
- Quality Function Deployment in Product Design
- Analytical Methods in Pharmaceuticals
- Advancements in Transdermal Drug Delivery
- Pharmacological Effects and Toxicity Studies
- Biochemical Analysis and Sensing Techniques
- Economics of Agriculture and Food Markets
- Drug Transport and Resistance Mechanisms
- FinTech, Crowdfunding, Digital Finance
- Herbal Medicine Research Studies
- Nicotinic Acetylcholine Receptors Study
- Ginseng Biological Effects and Applications
- Traditional Chinese Medicine Studies
- melanin and skin pigmentation
Southern Medical University
2023
Purdue University West Lafayette
2011-2021
Geely (China)
2011
Chery Automobile (China)
2011
New York University
2007
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. provides concise overviews, mostly tabular format, key properties approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There an emphasis on selective pharmacology (where available), plus links open access knowledgebase source targets their ligands (https://www.guidetopharmacology.org/), which more detailed views target ligand properties. Although constitutes almost...
Different objectives such as category demand expansion or market share stealing warrant the use of different marketing instruments. To help brand managers make informed decisions, it is essential that mix models appropriately measure their effects. Random Utility Models have been applied to this problem might not be adequate because they do allow effects instruments one spillover preference for competing alternatives. Additionally, Invariant Proportion Substitution (IPS) property, which in...
The practice of detailing in the marketing prescription drugs is undergoing significant changes. For instance, September 2013, Physician Payment Sunshine Act went into full effect. accompanying transparency requirements have prompted physician practices and hospitals to severely restrict pharmaceutical sales representatives’ direct access their physicians. Despite all attention popular press, scant scholarly research has investigated how these restrictions on impact behavior competitive To...
We study, using a stylized analytical model, an entrepreneur's design of the optimal product menu for crowdfunding together with choice funding target. find that in contrast to prior literature on crowdfunding, downward quality distortion low‐quality under can be higher, lesser or even non‐existent than traditional selling. also show as alternative selling is only attractive presence non‐zero fixed cost. Our findings provide important implications entrepreneurs optimizing their project design.
Against the backdrop of accelerated global industrial transformation and increasingly prominent environmental social issues, manufacturing industry in Liaoning Province is under pressure upgrading. This article focuses on enterprises Province. By comprehensively applying literature research method case analysis method, it deeply analyzes internal connection influence mechanism between their ESG performance New-quality productivity. The purpose to reveal how empower upgrading enhance...
This paper examines the spillover effects of promotions when products from different firms are consumed in a bundle. Using data HIV/AIDS category, canonical example combination therapy, we estimate hierarchical Bayesian logit model across treatment regimens and show that detailing for one drug can increase demand other drugs often combined with focal drug. Such could lead to free riding by benefitting spillover. We investigate managerial policy implications via counterfactual simulations...
Melanin is synthesized by melanocytes, which are located in the basal layer of skin. After synthesis, melanin further deposited on surface skin to form black spots or chloasma. Tyrosinase a rate-limiting enzyme that plays an important role melanogenesis. Currently, there many drugs inhibit tyrosinase expression reduce Nevertheless, some these could reverse pharmacological effect other drugs, when used simultaneously.B16 mouse melanoma cells were treated with inhibitors licochalcone A and...
Enhancing the precision of drug-drug interaction (DDI) prediction is essential for improving drug safety and efficacy. The aim to identify most effective fraction metabolized by CY3A4 (fm) DDI using physiologically based pharmacokinetic (PBPK) models.The fm values were determined 33 approved drugs a human liver microsome in vitro measurements ADMET Predictor software silico predictions. Subsequently, these integrated into PBPK models GastroPlus platform. models, combined with ketoconazole...
Pharmaceutical firms continue to advertise more and prescription drugs directly consumers, advocating them discuss the focal health condition efficacy of advertised drug with their physicians. In this paper, we investigate effectiveness such direct-to-consumer advertising (DTCA) on different types patients. Specifically, examine impact DTCA patients affliction levels television versus print ads as an influence severely mildly afflicted visit Briefly, using data from erectile dysfunction...
The goal of this research is to jointly study physician prescription decisions and patient drug request behaviors. We have adopted a binary logit model multinomial (MNL) data with excessive zero requests MNL capture decisions. These models are further joined by flexible nonparametric multivariate distribution for their random effects. also adopt an analytically consistent expression interaction effects in our non-linear joint modeling framework. apply unique panel set from the Erectile...
To reply with the recycling rules of world and persistent progress vehicle, it is necessary to develop European "RRR" type-approval. The background, content process proprietary brand's type-approval were introduced. Calculation methods rate recovery also described.
ABSTRACT BACKGROUND AND PURPOSE Enhancing the precision of drug-drug interaction (DDI) prediction is essential for mitigating potential drug interactions and enhancing safety efficacy. This study aims to investigate impact in vitro silico approaches calculating fraction metabolized by CY3A4 (fm) on DDI accuracy identified most effective method improving using physiologically based pharmacokinetic (PBPK) models. EXPERIMENTAL APPROACH Both methods were utilized determine fm values 33 approved...